The relevance of using 3D cell cultures, in addition to 2D monolayer cultures, when evaluating breast cancer drug sensitivity and resistance

por Breslin, Susan, O'Driscoll, Lorraine
Publicado 2016

Neratinib resistance and cross-resistance to other HER2-targeted drugs due to increased activity of metabolism enzyme cytochrome P4503A4

por Breslin, Susan, Lowry, Michelle C, O'Driscoll, Lorraine
Publicado 2017

miR-630 targets IGF1R to regulate response to HER-targeting drugs and overall cancer cell progression in HER2 over-expressing breast cancer

por Corcoran, Claire, Rani, Sweta, Breslin, Susan, Gogarty, Martina, Ghobrial, Irene M, Crown, John, O’Driscoll, Lorraine
Publicado 2014

Resistance to HER2-targeted anti-cancer drugs is associated with immune evasion in cancer cells and their derived extracellular vesicles

por Martinez, Vanesa G., O'Neill, Sadhbh, Salimu, Josephine, Breslin, Susan, Clayton, Aled, Crown, John, O'Driscoll, Lorraine
Publicado 2017