Epigenetic modifications as therapeutic targets in atherosclerosis: a focus on DNA methylation and non-coding RNAs

por Sum, Hashum, Brewer, Alison C.
Publicado 2023

Redox regulation of gasotransmission in the vascular system: A focus on angiogenesis

por Mistry, Rajesh K., Brewer, Alison C.
Publicado 2017

Dysregulation of 2-oxoglutarate-dependent dioxygenases by hyperglycaemia: does this link diabetes and vascular disease?

por Green, Hannah L. H., Brewer, Alison C.
Publicado 2020

Redox signaling in cardiac myocytes

por Santos, Celio X.C., Anilkumar, Narayana, Zhang, Min, Brewer, Alison C., Shah, Ajay M.
Publicado 2011

Endothelial NADPH oxidase 4 protects against angiotensin II‐induced cardiac fibrosis and inflammation

por Wang, Minshu, Murdoch, Colin E., Brewer, Alison C., Ivetic, Aleksandar, Evans, Paul, Shah, Ajay M., Zhang, Min
Publicado 2021

Nox4 regulates Nrf2 and glutathione redox in cardiomyocytes in vivo

por Brewer, Alison C., Murray, Thomas V.A., Arno, Matthew, Zhang, Min, Anilkumar, Narayana P., Mann, Giovanni E., Shah, Ajay M.
Publicado 2011

Transcriptional Regulation of Cystathionine-γ-Lyase in Endothelial Cells by NADPH Oxidase 4-Dependent Signaling

por Mistry, Rajesh K., Murray, Thomas V. A., Prysyazhna, Oleksandra, Martin, Daniel, Burgoyne, Joseph R., Santos, Celio, Eaton, Philip, Shah, Ajay M., Brewer, Alison C.
Publicado 2016

Inducibility, but not stability, of atrial fibrillation is increased by NOX2 overexpression in mice

por Mighiu, Alexandra S, Recalde, Alice, Ziberna, Klemen, Carnicer, Ricardo, Tomek, Jakub, Bub, Gil, Brewer, Alison C, Verheule, Sander, Shah, Ajay M, Simon, Jillian N, Casadei, Barbara
Publicado 2021

Cell-specific effects of Nox2 on the acute and chronic response to myocardial infarction

por Sirker, Alexander, Murdoch, Colin E., Protti, Andrea, Sawyer, Greta J., Santos, Celio X.C., Martin, Daniel, Zhang, Xiaohong, Brewer, Alison C., Zhang, Min, Shah, Ajay M.
Publicado 2016

NADPH Oxidase-4 Driven Cardiac Macrophage Polarization Protects Against Myocardial Infarction–Induced Remodeling

por Mongue-Din, Heloise, Patel, Ashish S., Looi, Yee H., Grieve, David J., Anilkumar, Narayana, Sirker, Alexander, Dong, Xuebin, Brewer, Alison C., Zhang, Min, Smith, Alberto, Shah, Ajay M.
Publicado 2017

Nox2-deficient Tregs improve heart transplant outcomes via their increased graft recruitment and enhanced potency

por Trevelin, Silvia C., Zampetaki, Anna, Sawyer, Greta, Ivetic, Aleksandar, Brewer, Alison C., Smyth, Lesley Ann, Marelli-Berg, Federica, Köchl, Robert, Lechler, Robert I., Shah, Ajay M., Lombardi, Giovanna
Publicado 2021

Redox regulation of cardiomyocyte cell cycling via an ERK1/2 and c-Myc-dependent activation of cyclin D2 transcription

por Murray, Thomas V.A., Smyrnias, Ioannis, Schnelle, Moritz, Mistry, Rajesh K., Zhang, Min, Beretta, Matteo, Martin, Daniel, Anilkumar, Narayana, de Silva, Shana M., Shah, Ajay M., Brewer, Alison C.
Publicado 2015

Oxygen gradients can determine epigenetic asymmetry and cellular differentiation via differential regulation of Tet activity in embryonic stem cells

por Burr, Simon, Caldwell, Anna, Chong, Mei, Beretta, Matteo, Metcalf, Stephen, Hancock, Matthew, Arno, Matthew, Balu, Sucharitha, Kropf, Valeria Leon, Mistry, Rajesh K, Shah, Ajay M, Mann, Giovanni E, Brewer, Alison C
Publicado 2018

Fibroblast Nox2 (NADPH Oxidase-2) Regulates ANG II (Angiotensin II)–Induced Vascular Remodeling and Hypertension via Paracrine Signaling to Vascular Smooth Muscle Cells

por Harrison, Craig B., Trevelin, Silvia Cellone, Richards, Daniel A., Santos, Celio X.C., Sawyer, Greta, Markovinovic, Andrea, Zhang, Xiaohong, Zhang, Min, Brewer, Alison C., Yin, Xiaoke, Mayr, Manuel, Shah, Ajay M.
Publicado 2020

Contractile Function During Angiotensin-II Activation: Increased Nox2 Activity Modulates Cardiac Calcium Handling via Phospholamban Phosphorylation

por Zhang, Min, Prosser, Benjamin L., Bamboye, Moradeke A., Gondim, Antonio N.S., Santos, Celio X., Martin, Daniel, Ghigo, Alessandra, Perino, Alessia, Brewer, Alison C., Ward, Christopher W., Hirsch, Emilio, Lederer, W. Jonathan, Shah, Ajay M.
Publicado 2015

NADPH oxidase 4 regulates homocysteine metabolism and protects against acetaminophen-induced liver damage in mice

por Murray, Thomas V.A., Dong, Xuebin, Sawyer, Greta J., Caldwell, Anna, Halket, John, Sherwood, Roy, Quaglia, Alberto, Dew, Tracy, Anilkumar, Narayana, Burr, Simon, Mistry, Rajesh K., Martin, Daniel, Schröder, Katrin, Brandes, Ralf P., Hughes, Robin D., Shah, Ajay M., Brewer, Alison C.
Publicado 2015

Mutual Regulation of Epicardial Adipose Tissue and Myocardial Redox State by PPAR-γ/Adiponectin Signalling

por Antonopoulos, Alexios S., Margaritis, Marios, Verheule, Sander, Recalde, Alice, Sanna, Fabio, Herdman, Laura, Psarros, Costas, Nasrallah, Hussein, Coutinho, Patricia, Akoumianakis, Ioannis, Brewer, Alison C., Sayeed, Rana, Krasopoulos, George, Petrou, Mario, Tarun, Akansha, Tousoulis, Dimitris, Shah, Ajay M., Casadei, Barbara, Channon, Keith M., Antoniades, Charalambos
Publicado 2016

Distinct Regulatory Effects of Myeloid Cell and Endothelial Cell NAPDH Oxidase 2 on Blood Pressure

por Sag, Can Martin, Schnelle, Moritz, Zhang, Juqian, Murdoch, Colin E., Kossmann, Sabine, Protti, Andrea, Santos, Celio X.C., Sawyer, Greta, Zhang, Xiaohong, Mongue-Din, Heloise, Richards, Daniel A., Brewer, Alison C., Prysyazhna, Oleksandra, Maier, Lars S., Wenzel, Philip, Eaton, Philip J., Shah, Ajay M.
Publicado 2017

Nox4 reprograms cardiac substrate metabolism via protein O-GlcNAcylation to enhance stress adaptation

por Nabeebaccus, Adam A., Zoccarato, Anna, Hafstad, Anne D., Santos, Celio X.C., Aasum, Ellen, Brewer, Alison C., Zhang, Min, Beretta, Matteo, Yin, Xiaoke, West, James A., Schröder, Katrin, Griffin, Julian L., Eykyn, Thomas R., Abel, E. Dale, Mayr, Manuel, Shah, Ajay M.
Publicado 2017

Activation of TRPC6 channels is essential for lung ischaemia–reperfusion induced oedema in mice

por Weissmann, Norbert, Sydykov, Akylbek, Kalwa, Hermann, Storch, Ursula, Fuchs, Beate, Schnitzler, Michael Mederos y, Brandes, Ralf P., Grimminger, Friedrich, Meissner, Marcel, Freichel, Marc, Offermanns, Stefan, Veit, Florian, Pak, Oleg, Krause, Karl-Heinz, Schermuly, Ralph T., Brewer, Alison C, Schmidt, Harald H.H.W., Seeger, Werner, Shah, Ajay M., Gudermann, Thomas, Ghofrani, Hossein A., Dietrich, Alexander
Publicado 2012