Machine learning analysis of gene expression data reveals novel diagnostic and prognostic biomarkers and identifies therapeutic targets for soft tissue sarcomas

por van IJzendoorn, David G. P., Szuhai, Karoly, Briaire-de Bruijn, Inge H., Kostine, Marie, Kuijjer, Marieke L., Bovée, Judith V. M. G.
Publicado 2019

Utility of FOS as diagnostic marker for osteoid osteoma and osteoblastoma

por Lam, Suk Wai, Cleven, Arjen H. G., Kroon, Herman M., Briaire-de Bruijn, Inge H., Szuhai, Karoly, Bovée, Judith V. M. G.
Publicado 2019

SUMOylation Is Associated with Aggressive Behavior in Chondrosarcoma of Bone

por Kroonen, Jessie S., Kruisselbrink, Alwine B., Briaire-de Bruijn, Inge H., Olaofe, Olaejirinde O., Bovée, Judith V. M. G., Vertegaal, Alfred C. O.
Publicado 2021

Oestrogen receptor expression distinguishes non-ossifying fibroma from other giant cell containing bone tumours

por Cleven, Arjen H. G., Schreuder, Willem H., Groen, Eline, de Lange, Jan, Briaire-de Bruijn, Inge H., Bovée, Judith V. M. G.
Publicado 2022

Selection of Effective Therapies Using Three-Dimensional in vitro Modeling of Chondrosarcoma

por Palubeckaitė, Ieva, Venneker, Sanne, Briaire-de Bruijn, Inge H., van den Akker, Brendy E., Krol, Augustinus D., Gelderblom, Hans, Bovée, Judith V. M. G.
Publicado 2020

Inhibition of PARP Sensitizes Chondrosarcoma Cell Lines to Chemo- and Radiotherapy Irrespective of the IDH1 or IDH2 Mutation Status

por Venneker, Sanne, Kruisselbrink, Alwine B., Briaire-de Bruijn, Inge H., de Jong, Yvonne, van Wijnen, Andre J., Danen, Erik H.J., Bovée, Judith V.M.G.
Publicado 2019

Beyond the Influence of IDH Mutations: Exploring Epigenetic Vulnerabilities in Chondrosarcoma

por Venneker, Sanne, Kruisselbrink, Alwine B., Baranski, Zuzanna, Palubeckaite, Ieva, Briaire-de Bruijn, Inge H., Oosting, Jan, French, Pim J., Danen, Erik H. J., Bovée, Judith V. M. G.
Publicado 2020

NTRK fusions are extremely rare in bone tumours

por Lam, Suk Wai, Briaire‐de Bruijn, Inge H, van Wezel, Tom, Cleven, Arjen H G, Hogendoorn, Pancras C W, Cleton‐Jansen, Anne‐Marie, Bovée, Judith V M G
Publicado 2021

IDH1 or -2 mutations do not predict outcome and do not cause loss of 5-hydroxymethylcytosine or altered histone modifications in central chondrosarcomas

por Cleven, Arjen H. G., Suijker, Johnny, Agrogiannis, Georgios, Briaire-de Bruijn, Inge H., Frizzell, Norma, Hoekstra, Attje S., Wijers-Koster, Pauline M., Cleton-Jansen, Anne-Marie, Bovée, Judith V. M. G.
Publicado 2017

Establishment of an Academic Tissue Microarray Platform as a Tool for Soft Tissue Sarcoma Research

por Lee, Che-Jui, Wozniak, Agnieszka, Van Cann, Thomas, Timmermans, Iris, Wellens, Jasmien, Vanleeuw, Ulla, Briaire-de Bruijn, Inge H., Britschgi, Christian, Bovée, Judith V. M. G., Zlobec, Inti, Sciot, Raf, Schöffski, Patrick
Publicado 2021

IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma

por Kuijjer, Marieke L, Peterse, Elisabeth FP, van den Akker, Brendy EWM, Briaire-de Bruijn, Inge H, Serra, Massimo, Meza-Zepeda, Leonardo A, Myklebost, Ola, Hassan, A Bassim, Hogendoorn, Pancras CW, Cleton-Jansen, Anne-Marie
Publicado 2013

Radiotherapy resistance in chondrosarcoma cells; a possible correlation with alterations in cell cycle related genes

por de Jong, Yvonne, Ingola, Martha, Briaire-de Bruijn, Inge H., Kruisselbrink, Alwine B., Venneker, Sanne, Palubeckaite, Ieva, Heijs, Bram P. A. M., Cleton-Jansen, Anne-Marie, Haas, Rick L. M., Bovée, Judith V. M. G.
Publicado 2019

Vascular Tumor Recapitulated in Endothelial Cells from hiPSCs Engineered to Express the SERPINE1-FOSB Translocation

por van IJzendoorn, David G.P., Salvatori, Daniela C.F., Cao, Xu, van den Hil, Francijna, Briaire-de Bruijn, Inge H., de Jong, Danielle, Mei, Hailiang, Mummery, Christine L., Szuhai, Karoly, Bovée, Judith V.M.G., Orlova, Valeria V.
Publicado 2020

Cellular/intramuscular myxoma and grade I myxofibrosarcoma are characterized by distinct genetic alterations and specific composition of their extracellular matrix

por Willems, Stefan M, Mohseny, Alex B, Balog, Crina, Sewrajsing, Raj, Briaire-de Bruijn, Inge H, Knijnenburg, Jeroen, Cleton-Jansen, Anne-Marie, Sciot, Raf, Fletcher, Christopher D M, Deelder, André M, Szuhai, Karoly, Hensbergen, Paul J, Hogendoorn, Pancras C W
Publicado 2009

Increased infiltration of M2-macrophages, T-cells and PD-L1 expression in high grade leiomyosarcomas supports immunotherapeutic strategies

por Kostine, Marie, Briaire-de Bruijn, Inge H., Cleven, Arjen H. G., Vervat, Carly, Corver, Willem E., Schilham, Marco W., Van Beelen, Els, van Boven, Hester, Haas, Rick L., Italiano, Antoine, Cleton-Jansen, Anne-Marie, Bovée, Judith V. M. G.
Publicado 2017

Histone Deacetylase Inhibitors as a Therapeutic Strategy to Eliminate Neoplastic “Stromal” Cells from Giant Cell Tumors of Bone

por Venneker, Sanne, van Eenige, Robin, Kruisselbrink, Alwine B., Palubeckaitė, Ieva, Taliento, Alice E., Briaire-de Bruijn, Inge H., Hogendoorn, Pancras C. W., van de Sande, Michiel A. J., Gelderblom, Hans, Mei, Hailiang, Bovée, Judith V. M. G., Szuhai, Karoly
Publicado 2022

Expanding the Spectrum of EWSR1-NFATC2-rearranged Benign Tumors: A Common Genomic Abnormality in Vascular Malformation/Hemangioma and Simple Bone Cyst

por Ong, Sheena L.M., Lam, Suk Wai, van den Akker, Brendy E.W.M., Kroon, Herman M., Briaire-de Bruijn, Inge H., Cleven, Arjen H.G., Savci-Heijink, Dilara C., Cleton-Jansen, Anne-Marie, Baumhoer, Daniel, Szuhai, Karoly, Bovée, Judith V.M.G.
Publicado 2021

A screening-based approach identifies cell cycle regulators AURKA, CHK1 and PLK1 as targetable regulators of chondrosarcoma cell survival

por de Jong, Yvonne, Bennani, Fairuz, van Oosterwijk, Jolieke G., Alberti, Gaia, Baranski, Zuzanna, Wijers-Koster, Pauline, Venneker, Sanne, Briaire-de Bruijn, Inge H., van de Akker, Brendy E., Baelde, Hans, Cleton-Jansen, Anne-Marie, van de Water, Bob, Danen, Erik H.J., Bovée, Judith V.M.G.
Publicado 2019

Inhibition of mutant IDH1 decreases D-2-HG levels without affecting tumorigenic properties of chondrosarcoma cell lines

por Suijker, Johnny, Oosting, Jan, Koornneef, Annemarie, Struys, Eduard A., Salomons, Gajja S., Schaap, Frank G., Waaijer, Cathelijn J.F., Wijers-Koster, Pauline M., Briaire-de Bruijn, Inge H., Haazen, Lizette, Riester, Scott M., Dudakovic, Amel, Danen, Erik, Cleton-Jansen, Anne-Marie, van Wijnen, Andre J., Bovée, Judith V.M.G.
Publicado 2015

Inactivation of SDH and FH cause loss of 5hmC and increased H3K9me3 in paraganglioma/pheochromocytoma and smooth muscle tumors

por Hoekstra, Attje S., de Graaff, Marieke A., Briaire-de Bruijn, Inge H., Ras, Cor, Seifar, Reza Maleki, van Minderhout, Ivonne, Cornelisse, Cees J., Hogendoorn, Pancras C.W., Breuning, Martijn H., Suijker, Johnny, Korpershoek, Esther, Kunst, Henricus P.M., Frizzell, Norma, Devilee, Peter, Bayley, Jean-Pierre, Bovée, Judith V.M.G.
Publicado 2015