Pharmacology under the microscope: the use of fluorescence correlation spectroscopy to determine the properties of ligand–receptor complexes

por Briddon, Stephen J., Hill, Stephen J.
Publicado 2007

Micro-pharmacokinetics: Quantifying local drug concentration at live cell membranes

por Gherbi, Karolina, Briddon, Stephen J., Charlton, Steven J.
Publicado 2018

Fluorescence correlation spectroscopy, combined with bimolecular fluorescence complementation, reveals the effects of β-arrestin complexes and endocytic targeting on the membrane m...

por Kilpatrick, Laura E., Briddon, Stephen J., Holliday, Nicholas D.
Publicado 2012

Effect of a toggle switch mutation in TM6 of the human adenosine A(3) receptor on Gi protein-dependent signalling and Gi-independent receptor internalization

por Stoddart, Leigh A, Kellam, Barrie, Briddon, Stephen J, Hill, Stephen J
Publicado 2014

GRK Mediates μ-Opioid Receptor Plasma Membrane Reorganization

por Gondin, Arisbel B., Halls, Michelle L., Canals, Meritxell, Briddon, Stephen J.
Publicado 2019

Simple methods for quantifying super-resolved cortical actin

por Garlick, Evelyn, Faulkner, Emma L., Briddon, Stephen J., Thomas, Steven G.
Publicado 2022

NanoBiT Complementation to Monitor Agonist-Induced Adenosine A(1) Receptor Internalization

por Soave, Mark, Kellam, Barrie, Woolard, Jeanette, Briddon, Stephen J., Hill, Stephen J.
Publicado 2019

Kinetic analysis of antagonist-occupied adenosine-A(3) receptors within membrane microdomains of individual cells provides evidence of receptor dimerization and allosterism

por Corriden, Ross, Kilpatrick, Laura E., Kellam, Barrie, Briddon, Stephen J., Hill, Stephen J.
Publicado 2014

Negative cooperativity across β(1)-adrenoceptor homodimers provides insights into the nature of the secondary low-affinity CGP 12177 β1-adrenoceptor binding conformation

por Gherbi, Karolina, May, Lauren T., Baker, Jillian G., Briddon, Stephen J., Hill, Stephen J.
Publicado 2015

Allosteric interactions across native adenosine-A(3) receptor homodimers: quantification using single-cell ligand-binding kinetics

por May, Lauren T., Bridge, Lloyd J., Stoddart, Leigh A., Briddon, Stephen J., Hill, Stephen J.
Publicado 2011

Analysis of Sequence Divergence in Mammalian ABCGs Predicts a Structural Network of Residues That Underlies Functional Divergence

por Mitchell-White, James I., Stockner, Thomas, Holliday, Nicholas, Briddon, Stephen J., Kerr, Ian D.
Publicado 2021

Application of fluorescence correlation spectroscopy to study substrate binding in styrene maleic acid lipid copolymer encapsulated ABCG2

por Horsey, Aaron J., Briggs, Deborah A., Holliday, Nicholas D., Briddon, Stephen J., Kerr, Ian D.
Publicado 2020

A Non-imaging High Throughput Approach to Chemical Library Screening at the Unmodified Adenosine-A(3) Receptor in Living Cells

por Arruda, Maria Augusta, Stoddart, Leigh A., Gherbi, Karolina, Briddon, Stephen J., Kellam, Barrie, Hill, Stephen J.
Publicado 2017

Efficient G protein coupling is not required for agonist‐mediated internalization and membrane reorganization of the adenosine A(3) receptor

por Stoddart, Leigh A., Kilpatrick, Laura E., Corriden, Ross, Kellam, Barrie, Briddon, Stephen J., Hill, Stephen J.
Publicado 2021

Influence of fluorophore and linker composition on the pharmacology of fluorescent adenosine A(1) receptor ligands

por Baker, Jillian G, Middleton, Richard, Adams, Luke, May, Lauren T, Briddon, Stephen J, Kellam, Barrie, Hill, Stephen J
Publicado 2010

Fragment Screening at Adenosine-A(3) Receptors in Living Cells Using a Fluorescence-Based Binding Assay

por Stoddart, Leigh A., Vernall, Andrea J., Denman, Jessica L., Briddon, Stephen J., Kellam, Barrie, Hill, Stephen J.
Publicado 2012

Adenosine-A(3) receptors in neutrophil microdomains promote the formation of bacteria-tethering cytonemes

por Corriden, Ross, Self, Tim, Akong-Moore, Kathryn, Nizet, Victor, Kellam, Barrie, Briddon, Stephen J, Hill, Stephen J
Publicado 2013

Monitoring Allosteric Interactions with CXCR4 Using NanoBiT Conjugated Nanobodies

por Soave, Mark, Heukers, Raimond, Kellam, Barrie, Woolard, Jeanette, Smit, Martine J., Briddon, Stephen J., Hill, Stephen J.
Publicado 2020

Probing the binding of interleukin-23 to individual receptor components and the IL-23 heteromeric receptor complex in living cells using NanoBRET

por Lay, Charles S., Bridges, Angela, Goulding, Joelle, Briddon, Stephen J., Soloviev, Zoja, Craggs, Peter D., Hill, Stephen J.
Publicado 2022

Detection of genome‐edited and endogenously expressed G protein‐coupled receptors

por Soave, Mark, Stoddart, Leigh A., White, Carl W., Kilpatrick, Laura E., Goulding, Joëlle, Briddon, Stephen J., Hill, Stephen J.
Publicado 2021