To branch or to expand?

por Bridges, Esther M, Harris, Adrian L
Publicado 2016

Differential effects of HIF2α antagonist and HIF2α silencing in renal cancer and sensitivity to repurposed drugs

por Arnaiz, Esther, Miar, Ana, Bridges, Esther, Prasad, Naveen, Hatch, Stephanie B., Ebner, Daniel, Lawrie, Charles H., Harris, Adrian L.
Publicado 2021

CRISPR-Cas9 screen identifies oxidative phosphorylation as essential for cancer cell survival at low extracellular pH

por Michl, Johanna, Wang, Yunyi, Monterisi, Stefania, Blaszczak, Wiktoria, Beveridge, Ryan, Bridges, Esther M., Koth, Jana, Bodmer, Walter F., Swietach, Pawel
Publicado 2022

Solute exchange through gap junctions lessens the adverse effects of inactivating mutations in metabolite-handling genes

por Monterisi, Stefania, Michl, Johanna, Hulikova, Alzbeta, Koth, Jana, Bridges, Esther M, Hill, Amaryllis E, Abdullayeva, Gulnar, Bodmer, Walter F, Swietach, Pawel
Publicado 2022

Galectin-3 acts as an angiogenic switch to induce tumor angiogenesis via Jagged-1/Notch activation

por dos Santos, Sofia Nascimento, Sheldon, Helen, Pereira, Jonathas Xavier, Paluch, Christopher, Bridges, Esther M, El-Cheikh, Márcia Curry, Harris, Adrian L, Bernardes, Emerson Soares
Publicado 2017

RHOQ is induced by DLL4 and regulates angiogenesis by determining the intracellular route of the Notch intracellular domain

por Bridges, Esther, Sheldon, Helen, Kleibeuker, Esther, Ramberger, Evelyn, Zois, Christos, Barnard, Alun, Harjes, Ulrike, Li, Ji-Liang, Masiero, Massimo, MacLaren, Robert, Harris, Adrian
Publicado 2020

Role of Delta-like 4 in Jagged1-induced tumour angiogenesis and tumour growth

por Oon, Chern Ein, Bridges, Esther, Sheldon, Helen, Sainson, Richard C.A., Jubb, Adrian, Turley, Helen, Leek, Russell, Buffa, Francesca, Harris, Adrian L., Li, Ji-Liang
Publicado 2017

ELTD1 Activation Induces an Endothelial-EMT Transition to a Myofibroblast Phenotype

por Sheldon, Helen, Alexander, John, Bridges, Esther, Moreira, Lucia, Reilly, Svetlana, Ang, Koon Hwee, Wang, Dian, Lin, Salwa, Haider, Syed, Banham, Alison H., Harris, Adrian L.
Publicado 2021

WNT5A-ROR2 axis mediates VEGF dependence of BRAF mutant melanoma

por Coupe, Nicholas, Guo, Lina, Bridges, Esther, Campo, Leticia, Espinosa, Olivia, Colling, Richard, Marshall, Andrea, Nandakumar, Ashwin, van Stiphout, Ruud, Buffa, Francesca M., Corrie, Pippa G., Middleton, Mark R., Macaulay, Valentine M.
Publicado 2022

Disruption of hypoxia-inducible fatty acid binding protein 7 induces beige fat-like differentiation and thermogenesis in breast cancer cells

por Kawashima, Masahiro, Bensaad, Karim, Zois, Christos E., Barberis, Alessandro, Bridges, Esther, Wigfield, Simon, Lagerholm, Christoffer, Dmitriev, Ruslan I., Tokiwa, Mariko, Toi, Masakazu, Papkovsky, Dmitri B., Buffa, Francesca M., Harris, Adrian L.
Publicado 2020

Correction to: Disruption of hypoxia-inducible fatty acid binding protein 7 induces beige fat-like differentiation and thermogenesis in breast cancer cells

por Kawashima, Masahiro, Bensaad, Karim, Zois, Christos E., Barberis, Alessandro, Bridges, Esther, Wigfield, Simon, Lagerholm, Christoffer, Dmitriev, Ruslan I., Tokiwa, Mariko, Toi, Masakazu, Papkovsky, Dmitri B., Buffa, Francesca M., Harris, Adrian L.
Publicado 2020

Nuclear HER4 mediates acquired resistance to trastuzumab and is associated with poor outcome in HER2 positive breast cancer

por Nafi, Siti Norasikin Mohd, Generali, Daniele, Kramer-Marek, Gabriela, Gijsen, Merel, Strina, Carla, Cappelletti, Mariarosa, Andreis, Daniele, Haider, Syed, Li, Ji-Liang, Bridges, Esther, Capala, Jacek, Ioannis, Roxanis, Harris, Adrian L, Kong, Anthony
Publicado 2014

IGF-1R inhibition induces schedule-dependent sensitization of human melanoma to temozolomide

por Ramcharan, Roger, Aleksic, Tamara, Kamdoum, Wilfride Petnga, Gao, Shan, Pfister, Sophia X., Tanner, Jordan, Bridges, Esther, Asher, Ruth, Watson, Amanda J., Margison, Geoffrey P., Woodcock, Mick, Repapi, Emmanouela, Li, Ji-Liang, Middleton, Mark R., Macaulay, Valentine M.
Publicado 2015

ADAM10 mediates trastuzumab resistance and is correlated with survival in HER2 positive breast cancer

por Feldinger, Katharina, Generali, Daniele, Kramer-Marek, Gabriela, Gijsen, Merel, Ng, Tzi Bun, Wong, Jack Ho, Strina, Carla, Cappelletti, Mariarosa, Andreis, Daniele, Li, Ji-Liang, Bridges, Esther, Turley, Helen, Leek, Russell, Roxanis, Ioannis, Capala, Jacek, Murphy, Gillian, Harris, Adrian L., Kong, Anthony
Publicado 2014

Hypoxia-induced switch in SNAT2/SLC38A2 regulation generates endocrine resistance in breast cancer

por Morotti, Matteo, Bridges, Esther, Valli, Alessandro, Choudhry, Hani, Sheldon, Helen, Wigfield, Simon, Gray, Nicki, Zois, Christos E., Grimm, Fiona, Jones, Dylan, Teoh, Eugene J., Cheng, Wei-Chen, Lord, Simon, Anastasiou, Dimitrios, Haider, Syed, McIntyre, Alan, Goberdhan, Deborah C. I., Buffa, Francesca, Harris, Adrian L.
Publicado 2019

Liver glycogen phosphorylase is upregulated in glioblastoma and provides a metabolic vulnerability to high dose radiation

por Zois, Christos E., Hendriks, Anne M., Haider, Syed, Pires, Elisabete, Bridges, Esther, Kalamida, Dimitra, Voukantsis, Dimitrios, Lagerholm, B. Christoffer, Fehrmann, Rudolf S. N., den Dunnen, Wilfred F. A., Tarasov, Andrei I., Baba, Otto, Morris, John, Buffa, Francesca M., McCullagh, James S. O., Jalving, Mathilde, Harris, Adrian L.
Publicado 2022

Proline synthesis through PYCR1 is required to support cancer cell proliferation and survival in oxygen-limiting conditions

por Westbrook, Rebecca L., Bridges, Esther, Roberts, Jennie, Escribano-Gonzalez, Cristina, Eales, Katherine L., Vettore, Lisa A., Walker, Paul D., Vera-Siguenza, Elias, Rana, Himani, Cuozzo, Federica, Eskla, Kattri-Liis, Vellama, Hans, Shaaban, Abeer, Nixon, Colin, Luuk, Hendrik, Lavery, Gareth G., Hodson, David J., Harris, Adrian L., Tennant, Daniel A.
Publicado 2022

A Core Human Primary Tumor Angiogenesis Signature Identifies the Endothelial Orphan Receptor ELTD1 as a Key Regulator of Angiogenesis

por Masiero, Massimo, Simões, Filipa Costa, Han, Hee Dong, Snell, Cameron, Peterkin, Tessa, Bridges, Esther, Mangala, Lingegowda S., Wu, Sherry Yen-Yao, Pradeep, Sunila, Li, Demin, Han, Cheng, Dalton, Heather, Lopez-Berestein, Gabriel, Tuynman, Jurriaan B., Mortensen, Neil, Li, Ji-Liang, Patient, Roger, Sood, Anil K., Banham, Alison H., Harris, Adrian L., Buffa, Francesca M.
Publicado 2013

MEF2 transcription factors are key regulators of sprouting angiogenesis

por Sacilotto, Natalia, Chouliaras, Kira M., Nikitenko, Leonid L., Lu, Yao Wei, Fritzsche, Martin, Wallace, Marsha D., Nornes, Svanhild, García-Moreno, Fernando, Payne, Sophie, Bridges, Esther, Liu, Ke, Biggs, Daniel, Ratnayaka, Indrika, Herbert, Shane P., Molnár, Zoltán, Harris, Adrian L., Davies, Benjamin, Bond, Gareth L., Bou-Gharios, George, Schwarz, John J., De Val, Sarah
Publicado 2016

Corrigendum: MEF2 transcription factors are key regulators of sprouting angiogenesis

por Sacilotto, Natalia, Chouliaras, Kira M., Nikitenko, Leonid L., Lu, Yao Wei, Fritzsche, Martin, Wallace, Marsha D., Nornes, Svanhild, García-Moreno, Fernando, Payne, Sophie, Bridges, Esther, Liu, Ke, Biggs, Daniel, Ratnayaka, Indrika, Herbert, Shane P., Molnár, Zoltán, Harris, Adrian L., Davies, Benjamin, Bond, Gareth L., Bou-Gharios, George, Schwarz, John J., De Val, Sarah
Publicado 2022