Mechanisms Underlying Overactive Bladder and Interstitial Cystitis/Painful Bladder Syndrome

por Grundy, Luke, Caldwell, Ashlee, Brierley, Stuart M.
Publicado 2018

Pain-Causing Venom Peptides: Insights into Sensory Neuron Pharmacology

por Jami, Sina, Erickson, Andelain, Brierley, Stuart M., Vetter, Irina
Publicado 2017

Spinal Afferent Innervation of the Colon and Rectum

por Brierley, Stuart M., Hibberd, Timothy J., Spencer, Nick J.
Publicado 2018

Pain in Endometriosis

por Maddern, Jessica, Grundy, Luke, Castro, Joel, Brierley, Stuart M.
Publicado 2020

Purinergic receptor mediated calcium signalling in urothelial cells

por Chess-Williams, Russell, Sellers, Donna J., Brierley, Stuart M., Grundy, David, Grundy, Luke
Publicado 2019

Identifying the Ion Channels Responsible for Signaling Gastro-Intestinal Based Pain

por Brierley, Stuart M., Hughes, Patrick A., Harrington, Andrea M., Rychkov, Grigori Y., Blackshaw, L. Ashley
Publicado 2010

Identification of a Quorum Sensing-Dependent Communication Pathway Mediating Bacteria-Gut-Brain Cross Talk

por Uhlig, Friederike, Grundy, Luke, Garcia-Caraballo, Sonia, Brierley, Stuart M., Foster, Simon J., Grundy, David
Publicado 2020

Experimentally Induced Bladder Permeability Evokes Bladder Afferent Hypersensitivity in the Absence of Inflammation

por Grundy, Luke, Caldwell, Ashlee, Lumsden, Amanda, Mohammadi, Ehsan, Hannig, Gerhard, Greenwood Van-Meervald, Beverley, Brierley, Stuart M.
Publicado 2020

TGR5 agonists induce peripheral and central hypersensitivity to bladder distension

por Caldwell, Ashlee, Grundy, Luke, Harrington, Andrea M., Garcia-Caraballo, Sonia, Castro, Joel, Bunnett, Nigel W., Brierley, Stuart M.
Publicado 2022

Clodronate Treatment Prevents Vaginal Hypersensitivity in a Mouse Model of Vestibulodynia

por Castro, Joel, Harrington, Andrea M., Chegini, Fariba, Matusica, Dusan, Spencer, Nick J., Brierley, Stuart M., Haberberger, Rainer V., Barry, Christine M.
Publicado 2022

The T-type calcium channel Ca(V)3.2 regulates bladder afferent responses to mechanical stimuli

por Grundy, Luke, Tay, Cindy, Christie, Stewart, Harrington, Andrea M., Castro, Joel, Cardoso, Fernanda C., Lewis, Richard J., Zagorodnyuk, Vladimir, Brierley, Stuart M.
Publicado 2023

Olorinab (APD371), a peripherally acting, highly selective, full agonist of the cannabinoid receptor 2, reduces colitis-induced acute and chronic visceral hypersensitivity in roden...

por Castro, Joel, Garcia-Caraballo, Sonia, Maddern, Jessica, Schober, Gudrun, Lumsden, Amanda, Harrington, Andrea, Schmiel, Shirdi, Lindstrom, Beatriz, Adams, John, Brierley, Stuart M.
Publicado 2022

Disengaging spinal afferent nerve communication with the brain in live mice

por Kyloh, Melinda A., Hibberd, Timothy J., Castro, Joel, Harrington, Andrea M., Travis, Lee, Dodds, Kelsi N., Wiklendt, Lukasz, Brierley, Stuart M., Zagorodnyuk, Vladimir P., Spencer, Nick J.
Publicado 2022

α-Conotoxin Vc1.1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABA(B) receptors

por Castro, Joel, Harrington, Andrea M, Garcia-Caraballo, Sonia, Maddern, Jessica, Grundy, Luke, Zhang, Jingming, Page, Guy, Miller, Paul E, Craik, David J, Adams, David J, Brierley, Stuart M
Publicado 2017

Design of a Stable Cyclic Peptide Analgesic Derived from Sunflower Seeds that Targets the κ-Opioid Receptor for the Treatment of Chronic Abdominal Pain

por Muratspahić, Edin, Tomašević, Nataša, Koehbach, Johannes, Duerrauer, Leopold, Hadžić, Seid, Castro, Joel, Schober, Gudrun, Sideromenos, Spyridon, Clark, Richard J., Brierley, Stuart M., Craik, David J., Gruber, Christian W.
Publicado 2021

Apelin targets gut contraction to control glucose metabolism via the brain

por Fournel, Audren, Drougard, Anne, Duparc, Thibaut, Marlin, Alysson, Brierley, Stuart M, Castro, Joel, Le-Gonidec, Sophie, Masri, Bernard, Colom, André, Lucas, Alexandre, Rousset, Perrine, Cenac, Nicolas, Vergnolle, Nathalie, Valet, Philippe, Cani, Patrice D, Knauf, Claude
Publicado 2017

Multiple sodium channel isoforms mediate the pathological effects of Pacific ciguatoxin-1

por Inserra, Marco C., Israel, Mathilde R., Caldwell, Ashlee, Castro, Joel, Deuis, Jennifer R., Harrington, Andrea M., Keramidas, Angelo, Garcia-Caraballo, Sonia, Maddern, Jessica, Erickson, Andelain, Grundy, Luke, Rychkov, Grigori Y., Zimmermann, Katharina, Lewis, Richard J., Brierley, Stuart M., Vetter, Irina
Publicado 2017

Activation of pruritogenic TGR5, MrgprA3, and MrgprC11 on colon-innervating afferents induces visceral hypersensitivity

por Castro, Joel, Harrington, Andrea M., Lieu, TinaMarie, Garcia-Caraballo, Sonia, Maddern, Jessica, Schober, Gudrun, O’Donnell, Tracey, Grundy, Luke, Lumsden, Amanda L., Miller, Paul, Ghetti, Andre, Steinhoff, Martin S., Poole, Daniel P., Dong, Xinzhong, Chang, Lin, Bunnett, Nigel W., Brierley, Stuart M.
Publicado 2019

Selective spider toxins reveal a role for Na(v)1.1 channel in mechanical pain

por Osteen, Jeremiah D., Herzig, Volker, Gilchrist, John, Emrick, Joshua J., Zhang, Chuchu, Wang, Xidao, Castro, Joel, Garcia-Caraballo, Sonia, Grundy, Luke, Rychkov, Grigori Y., Weyer, Andy D., Dekan, Zoltan, Undheim, Eivind A. B., Alewood, Paul, Stucky, Cheryl L., Brierley, Stuart M., Basbaum, Allan I., Bosmans, Frank, King, Glenn F., Julius, David
Publicado 2016