Subcellular transcriptome alterations in a cell culture model of spinal muscular atrophy point to widespread defects in axonal growth and presynaptic differentiation

por Saal, Lena, Briese, Michael, Kneitz, Susanne, Glinka, Michael, Sendtner, Michael
Publicado 2014

Whole transcriptome profiling reveals the RNA content of motor axons

por Briese, Michael, Saal, Lena, Appenzeller, Silke, Moradi, Mehri, Baluapuri, Apoorva, Sendtner, Michael
Publicado 2016

hnRNP R negatively regulates transcription by modulating the association of P‐TEFb with 7SK and BRD4

por Ji, Changhe, Deng, Chunchu, Antor, Katharina, Bischler, Thorsten, Schneider, Cornelius, Fischer, Utz, Sendtner, Michael, Briese, Michael
Publicado 2022

iCLIP Predicts the Dual Splicing Effects of TIA-RNA Interactions

por Wang, Zhen, Kayikci, Melis, Briese, Michael, Zarnack, Kathi, Luscombe, Nicholas M., Rot, Gregor, Zupan, Blaž, Curk, Tomaž, Ule, Jernej
Publicado 2010

CELF4 Regulates Translation and Local Abundance of a Vast Set of mRNAs, Including Genes Associated with Regulation of Synaptic Function

por Wagnon, Jacy L., Briese, Michael, Sun, Wenzhi, Mahaffey, Connie L., Curk, Tomaž, Rot, Gregor, Ule, Jernej, Frankel, Wayne N.
Publicado 2012

hnRNP R and its main interactor, the noncoding RNA 7SK, coregulate the axonal transcriptome of motoneurons

por Briese, Michael, Saal-Bauernschubert, Lena, Ji, Changhe, Moradi, Mehri, Ghanawi, Hanaa, Uhl, Michael, Appenzeller, Silke, Backofen, Rolf, Sendtner, Michael
Publicado 2018

Cytosolic Ptbp2 modulates axon growth in motoneurons through axonal localization and translation of Hnrnpr

por Salehi, Saeede, Zare, Abdolhossein, Prezza, Gianluca, Bader, Jakob, Schneider, Cornelius, Fischer, Utz, Meissner, Felix, Mann, Matthias, Briese, Michael, Sendtner, Michael
Publicado 2023

Deletion of smn-1, the Caenorhabditis elegans ortholog of the spinal muscular atrophy gene, results in locomotor dysfunction and reduced lifespan

por Briese, Michael, Esmaeili, Behrooz, Fraboulet, Sandrine, Burt, Emma C., Christodoulou, Stefanos, Towers, Paula R., Davies, Kay E., Sattelle, David B.
Publicado 2009

Interaction of 7SK with the Smn complex modulates snRNP production

por Ji, Changhe, Bader, Jakob, Ramanathan, Pradhipa, Hennlein, Luisa, Meissner, Felix, Jablonka, Sibylle, Mann, Matthias, Fischer, Utz, Sendtner, Michael, Briese, Michael
Publicado 2021

Absence of Plekhg5 Results in Myelin Infoldings Corresponding to an Impaired Schwann Cell Autophagy, and a Reduced T-Cell Infiltration Into Peripheral Nerves

por Lüningschrör, Patrick, Slotta, Carsten, Heimann, Peter, Briese, Michael, Weikert, Ulrich M., Massih, Bita, Appenzeller, Silke, Sendtner, Michael, Kaltschmidt, Christian, Kaltschmidt, Barbara
Publicado 2020

Loss of Tdp-43 disrupts the axonal transcriptome of motoneurons accompanied by impaired axonal translation and mitochondria function

por Briese, Michael, Saal-Bauernschubert, Lena, Lüningschrör, Patrick, Moradi, Mehri, Dombert, Benjamin, Surrey, Verena, Appenzeller, Silke, Deng, Chunchu, Jablonka, Sibylle, Sendtner, Michael
Publicado 2020

Loss of full-length hnRNP R isoform impairs DNA damage response in motoneurons by inhibiting Yb1 recruitment to chromatin

por Ghanawi, Hanaa, Hennlein, Luisa, Zare, Abdolhossein, Bader, Jakob, Salehi, Saeede, Hornburg, Daniel, Ji, Changhe, Sivadasan, Rajeeve, Drepper, Carsten, Meissner, Felix, Mann, Matthias, Jablonka, Sibylle, Briese, Michael, Sendtner, Michael
Publicado 2021

Plastin 3 rescues cell surface translocation and activation of TrkB in spinal muscular atrophy

por Hennlein, Luisa, Ghanawi, Hanaa, Gerstner, Florian, Palominos García, Eduardo, Yildirim, Ezgi, Saal-Bauernschubert, Lena, Moradi, Mehri, Deng, Chunchu, Klein, Teresa, Appenzeller, Silke, Sauer, Markus, Briese, Michael, Simon, Christian, Sendtner, Michael, Jablonka, Sibylle
Publicado 2023

Characterising the RNA targets and position-dependent splicing regulation by TDP-43; implications for neurodegenerative diseases

por Tollervey, James R., Curk, Tomaž, Rogelj, Boris, Briese, Michael, Cereda, Matteo, Kayikci, Melis, Hortobágyi, Tibor, Nishimura, Agnes L., Župunski, Vera, Patani, Rickie, Chandran, Siddharthan, Rot, Gregor, Zupan, Blaž, Shaw, Christopher E., Ule, Jernej
Publicado 2011

Recursive splicing in long vertebrate genes

por Sibley, Christopher R, Emmett, Warren, Blazquez, Lorea, Faro, Ana, Haberman, Nejc, Briese, Michael, Trabzuni, Daniah, Ryten, Mina, Weale, Michael E, Hardy, John, Modic, Miha, Curk, Tomaž, Wilson, Stephen W, Plagnol, Vincent, Ule, Jernej
Publicado 2015

R-Roscovitine Improves Motoneuron Function in Mouse Models for Spinal Muscular Atrophy

por Tejero, Rocio, Balk, Stefanie, Franco-Espin, Julio, Ojeda, Jorge, Hennlein, Luisa, Drexl, Hans, Dombert, Benjamin, Clausen, Jan-Dierk, Torres-Benito, Laura, Saal-Bauernschubert, Lena, Blum, Robert, Briese, Michael, Appenzeller, Silke, Tabares, Lucia, Jablonka, Sibylle
Publicado 2020

A systems view of spliceosomal assembly and branchpoints with iCLIP

por Briese, Michael, Haberman, Nejc, Sibley, Christopher R., Faraway, Rupert, Elser, Andrea S., Chakrabarti, Anob M., Wang, Zhen, König, Julian, Perera, David, Wickramasinghe, Vihandha O., Venkitaraman, Ashok R., Luscombe, Nicholas M., Saieva, Luciano, Pellizzoni, Livio, Smith, Christopher W.J., Curk, Tomaž, Ule, Jernej
Publicado 2019

Voltage-independent GluN2A-type NMDA receptor Ca(2+) signaling promotes audiogenic seizures, attentional and cognitive deficits in mice

por Bertocchi, Ilaria, Eltokhi, Ahmed, Rozov, Andrey, Chi, Vivan Nguyễn, Jensen, Vidar, Bus, Thorsten, Pawlak, Verena, Serafino, Marta, Sonntag, Hannah, Yang, Boyi, Burnashev, Nail, Li, Shi-Bin, Obenhaus, Horst A., Both, Martin, Niewoehner, Burkhard, Single, Frank N., Briese, Michael, Boerner, Thomas, Gass, Peter, Rawlins, John Nick P., Köhr, Georg, Bannerman, David M., Sprengel, Rolf
Publicado 2021

Author Correction: Voltage-independent GluN2A-type NMDA receptor Ca(2+) signaling promotes audiogenic seizures, attentional and cognitive deficits in mice

por Bertocchi, Ilaria, Eltokhi, Ahmed, Rozov, Andrey, Chi, Vivan Nguyễn, Jensen, Vidar, Bus, Thorsten, Pawlak, Verena, Serafino, Marta, Sonntag, Hannah, Yang, Boyi, Burnashev, Nail, Li, Shi-Bin, Obenhaus, Horst A., Both, Martin, Niewoehner, Burkhard, Single, Frank N., Briese, Michael, Boerner, Thomas, Gass, Peter, Rawlins, John Nick P., Köhr, Georg, Bannerman, David M., Sprengel, Rolf
Publicado 2021