Quercetin and luteolin are single-digit micromolar inhibitors of the SARS-CoV-2 RNA-dependent RNA polymerase

por Munafò, Federico, Donati, Elisa, Brindani, Nicoletta, Ottonello, Giuliana, Armirotti, Andrea, De Vivo, Marco
Publicado 2022

Design, synthesis, docking, and biochemical characterization of non-nucleoside SARS-CoV-2 RdRp inhibitors

por Brindani, Nicoletta, Munafò, Federico, Menichetti, Andrea, Donati, Elisa, Nigro, Michela, Ottonello, Giuliana, Armirotti, Andrea, De Vivo, Marco
Publicado 2023

Design, Synthesis, Dynamic Docking, Biochemical Characterization, and in Vivo Pharmacokinetics Studies of Novel Topoisomerase II Poisons with Promising Antiproliferative Activity

por Arencibia, Jose M., Brindani, Nicoletta, Franco-Ulloa, Sebastian, Nigro, Michela, Kuriappan, Jissy Akkarapattiakal, Ottonello, Giuliana, Bertozzi, Sine Mandrup, Summa, Maria, Girotto, Stefania, Bertorelli, Rosalia, Armirotti, Andrea, De Vivo, Marco
Publicado 2020

Design, Synthesis, In Vitro and In Vivo Characterization of CDC42 GTPase Interaction Inhibitors for the Treatment of Cancer

por Brindani, Nicoletta, Vuong, Linh M., Acquistapace, Isabella Maria, La Serra, Maria Antonietta, Ortega, José Antonio, Veronesi, Marina, Bertozzi, Sine Mandrup, Summa, Maria, Girotto, Stefania, Bertorelli, Rosalia, Armirotti, Andrea, Ganesan, Anand K., De Vivo, Marco
Publicado 2023

Identification, Structure–Activity Relationship, and Biological Characterization of 2,3,4,5-Tetrahydro-1H-pyrido[4,3-b]indoles as a Novel Class of CFTR Potentiators

por Brindani, Nicoletta, Gianotti, Ambra, Giovani, Simone, Giacomina, Francesca, Di Fruscia, Paolo, Sorana, Federico, Bertozzi, Sine Mandrup, Ottonello, Giuliana, Goldoni, Luca, Penna, Ilaria, Russo, Debora, Summa, Maria, Bertorelli, Rosalia, Ferrera, Loretta, Pesce, Emanuela, Sondo, Elvira, Galietta, Luis J. V., Bandiera, Tiziano, Pedemonte, Nicoletta, Bertozzi, Fabio
Publicado 2020

5-(Hydroxyphenyl)-γ-Valerolactone-Sulfate, a Key Microbial Metabolite of Flavan-3-ols, Is Able to Reach the Brain: Evidence from Different in Silico, In Vitro and In Vivo Experimen...

por Angelino, Donato, Carregosa, Diogo, Domenech-Coca, Cristina, Savi, Monia, Figueira, Inês, Brindani, Nicoletta, Jang, Saebyeol, Lakshman, Sukla, Molokin, Aleksey, Urban, Joseph F., Davis, Cindy D., Brito, Maria Alexandra, Kim, Kwang Sik, Brighenti, Furio, Curti, Claudio, Bladé, Cinta, del Bas, Josep M., Stilli, Donatella, Solano-Aguilar, Gloria I., dos Santos, Claudia Nunes, del Rio, Daniele, Mena, Pedro
Publicado 2019

Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer

por Jahid, Sohail, Ortega, Jose A., Vuong, Linh M., Acquistapace, Isabella Maria, Hachey, Stephanie J., Flesher, Jessica L., La Serra, Maria Antonietta, Brindani, Nicoletta, La Sala, Giuseppina, Manigrasso, Jacopo, Arencibia, Jose M., Bertozzi, Sine Mandrup, Summa, Maria, Bertorelli, Rosalia, Armirotti, Andrea, Jin, Rongsheng, Liu, Zheng, Chen, Chi-Fen, Edwards, Robert, Hughes, Christopher C.W., De Vivo, Marco, Ganesan, Anand K.
Publicado 2022