Organic Carbamates in Drug Design and Medicinal Chemistry

por Ghosh, Arun K., Brindisi, Margherita
Publicado 2015

Amide Bonds Meet Flow Chemistry: A Journey into Methodologies and Sustainable Evolution

por Alfano, Antonella Ilenia, Lange, Heiko, Brindisi, Margherita
Publicado 2022

Asymmetric Diels–Alder reaction of 3-(acyloxy)acryloyl oxazolidinones: optically active synthesis of a high-affinity ligand for potent HIV-1 protease inhibitors

por Ghosh, Arun K., Grillo, Alessandro, Kovela, Satish, Brindisi, Margherita
Publicado 2019

Editorial: Multi-target directed ligands for the treatment of cancer

por Brindisi, Margherita, Kessler, Sonja M., Kumar, Vinod, Zwergel, Clemens
Publicado 2022

Chasing a Breath of Fresh Air in Cystic Fibrosis (CF): Therapeutic Potential of Selective HDAC6 Inhibitors to Tackle Multiple Pathways in CF Pathophysiology

por Barone, Simona, Cassese, Emilia, Alfano, Antonella Ilenia, Brindisi, Margherita, Summa, Vincenzo
Publicado 2022

Computational Tool for Fast in silico Evaluation of hERG K(+) Channel Affinity

por Chemi, Giulia, Gemma, Sandra, Campiani, Giuseppe, Brogi, Simone, Butini, Stefania, Brindisi, Margherita
Publicado 2017

Dopamine D3 Receptor Antagonists as Potential Therapeutics for the Treatment of Neurological Diseases

por Maramai, Samuele, Gemma, Sandra, Brogi, Simone, Campiani, Giuseppe, Butini, Stefania, Stark, Holger, Brindisi, Margherita
Publicado 2016

Continuous-Flow Technology for Chemical Rearrangements: A Powerful Tool to Generate Pharmaceutically Relevant Compounds

por Alfano, Antonella Ilenia, Pelliccia, Sveva, Rossino, Giacomo, Chianese, Orazio, Summa, Vincenzo, Collina, Simona, Brindisi, Margherita
Publicado 2023

Coupling Interrupted Fischer and Multicomponent Joullié‐Ugi to Chase Chemical Diversity: from Batch to Sustainable Flow Synthesis of Peptidomimetics

por Alfano, Antonella Ilenia, Buommino, Elisabetta, Ferraro, Maria Grazia, Irace, Carlo, Zampella, Angela, Lange, Heiko, Brindisi, Margherita
Publicado 2021

In silico study of subtilisin-like protease 1 (SUB1) from different Plasmodium species in complex with peptidyl-difluorostatones and characterization of potent pan-SUB1 inhibitors

por Brogi, Simone, Giovani, Simone, Brindisi, Margherita, Gemma, Sandra, Novellino, Ettore, Campiani, Giuseppe, Blackman, Michael J., Butini, Stefania
Publicado 2016

Rejuvenating the [1, 2, 3]-triazolo [1,5-a]quinoxalin-4(5H)-one scaffold: Synthesis and derivatization in a sustainable guise and preliminary antimicrobial evaluation

por Pelliccia, Sveva, Alfano, Antonella Ilenia, Gomes Da Assunção, Beatriz Ramos, Turco, Luigia, Lembo, Francesca, Summa, Vincenzo, Buommino, Elisabetta, Brindisi, Margherita
Publicado 2023

Identification of Novel 3-Hydroxy-pyran-4-One Derivatives as Potent HIV-1 Integrase Inhibitors Using in silico Structure-Based Combinatorial Library Design Approach

por Sirous, Hajar, Chemi, Giulia, Gemma, Sandra, Butini, Stefania, Debyser, Zeger, Christ, Frauke, Saghaie, Lotfollah, Brogi, Simone, Fassihi, Afshin, Campiani, Giuseppe, Brindisi, Margherita
Publicado 2019

Easy access to α-ketoamides as SARS-CoV-2 and MERS M(pro) inhibitors via the PADAM oxidation route

por Pelliccia, Sveva, Cerchia, Carmen, Esposito, Francesca, Cannalire, Rolando, Corona, Angela, Costanzi, Elisa, Kuzikov, Maria, Gribbon, Philip, Zaliani, Andrea, Brindisi, Margherita, Storici, Paola, Tramontano, Enzo, Summa, Vincenzo
Publicado 2022

Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking

por Brindisi, Margherita, Brogi, Simone, Relitti, Nicola, Vallone, Alessandra, Butini, Stefania, Gemma, Sandra, Novellino, Ettore, Colotti, Gianni, Angiulli, Gabriella, Di Chiaro, Francesco, Fiorillo, Annarita, Ilari, Andrea, Campiani, Giuseppe
Publicado 2015

Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structu...

por Stefanelli, Irina, Corona, Angela, Cerchia, Carmen, Cassese, Emilia, Improta, Salvatore, Costanzi, Elisa, Pelliccia, Sveva, Morasso, Stefano, Esposito, Francesca, Paulis, Annalaura, Scognamiglio, Sante, Di Leva, Francesco Saverio, Storici, Paola, Brindisi, Margherita, Tramontano, Enzo, Cannalire, Rolando, Summa, Vincenzo
Publicado 2023

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–7

por Gütschow, Michael, Vanden Eynde, Jean Jacques, Jampilek, Josef, Kang, CongBao, Mangoni, Arduino A., Fossa, Paola, Karaman, Rafik, Trabocchi, Andrea, Scott, Peter J. H., Reynisson, Jóhannes, Rapposelli, Simona, Galdiero, Stefania, Winum, Jean-Yves, Brullo, Chiara, Prokai-Tatrai, Katalin, Sharma, Arun K., Schapira, Matthieu, Azuma, Yasu-Taka, Cerchia, Laura, Spetea, Mariana, Torri, Giangiacomo, Collina, Simona, Geronikaki, Athina, García-Sosa, Alfonso T., Vasconcelos, M. Helena, Sousa, Maria Emília, Kosalec, Ivan, Tuccinardi, Tiziano, Duarte, Iola F., Salvador, Jorge A. R., Bertinaria, Massimo, Pellecchia, Maurizio, Amato, Jussara, Rastelli, Giulio, Gomes, Paula A. C., Guedes, Rita C., Sabatier, Jean-Marc, Estévez-Braun, Ana, Pagano, Bruno, Mangani, Stefano, Ragno, Rino, Kokotos, George, Brindisi, Margherita, González, Florenci V., Borges, Fernanda, Miloso, Mariarosaria, Rautio, Jarkko, Muñoz-Torrero, Diego
Publicado 2020