Fragment Screening Yields a Small‐Molecule Stabilizer of 14‐3‐3 Dimers That Modulates Client Protein Interactions

por Brink, Hendrik J., Riemens, Rick, Thee, Stephanie, Beishuizen, Berend, da Costa Pereira, Daniel, Wijtmans, Maikel, de Esch, Iwan, Smit, Martine J., de Boer, Albertus H.
Publicado 2022

Fusicoccin-A Targets Cancerous Inhibitor of Protein Phosphatase 2A by Stabilizing a C-Terminal Interaction with 14-3-3

por Brink, Hendrik J., van Senten, Jeffrey R., De Vries-van Leeuwen, Ingrid J., da Costa Pereira, Daniel, Piersma, Sander R., Jimenez, Connie R., Centorrino, Federica, Ottmann, Christian, Siderius, Marco, Smit, Martine J., de Boer, Albertus H.
Publicado 2022