Easy quantitative assessment of genome editing by sequence trace decomposition

por Brinkman, Eva K., Chen, Tao, Amendola, Mario, van Steensel, Bas
Publicado 2014

Protocol: A Multiplexed Reporter Assay to Study Effects of Chromatin Context on DNA Double-Strand Break Repair

por Schep, Ruben, Leemans, Christ, Brinkman, Eva K., van Schaik, Tom, van Steensel, Bas
Publicado 2022

Kinetics and Fidelity of the Repair of Cas9-Induced Double-Strand DNA Breaks

por Brinkman, Eva K., Chen, Tao, de Haas, Marcel, Holland, Hanna A., Akhtar, Waseem, van Steensel, Bas
Publicado 2018

Intrinsic deletion at 10q23.31, including the PTEN gene locus, is aggravated upon CRISPR-Cas9–mediated genome engineering in HAP1 cells mimicking cancer profiles

por Geng, Keyi, Merino, Lara G, Veiga, Raül G, Sommerauer, Christian, Epperlein, Janine, Brinkman, Eva K, Kutter, Claudia
Publicado 2023

Easy quantification of template-directed CRISPR/Cas9 editing

por Brinkman, Eva K, Kousholt, Arne N, Harmsen, Tim, Leemans, Christ, Chen, Tao, Jonkers, Jos, van Steensel, Bas
Publicado 2018

Mapping 3D genome organization relative to nuclear compartments using TSA-Seq as a cytological ruler

por Chen, Yu, Zhang, Yang, Wang, Yuchuan, Zhang, Liguo, Brinkman, Eva K., Adam, Stephen A., Goldman, Robert, van Steensel, Bas, Ma, Jian, Belmont, Andrew S.
Publicado 2018

A single double-strand break system reveals repair dynamics and mechanisms in heterochromatin and euchromatin

por Janssen, Aniek, Breuer, Gregory A., Brinkman, Eva K., van der Meulen, Annelot I., Borden, Sean V., van Steensel, Bas, Bindra, Ranjit S., LaRocque, Jeannine R., Karpen, Gary H.
Publicado 2016

Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance

por Schep, Ruben, Brinkman, Eva K., Leemans, Christ, Vergara, Xabier, van der Weide, Robin H., Morris, Ben, van Schaik, Tom, Manzo, Stefano G., Peric-Hupkes, Daniel, van den Berg, Jeroen, Beijersbergen, Roderick L., Medema, René H., van Steensel, Bas
Publicado 2021