Plectin in Cancer: From Biomarker to Therapeutic Target

por Perez, Samantha M., Brinton, Lindsey T., Kelly, Kimberly A.
Publicado 2021

Registered report: Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

por Evans, James, Essex, Anthony, Xin, Hong, Amitai, Nurith, Brinton, Lindsey, Griner, Erin
Publicado 2015

PHASTpep: Analysis Software for Discovery of Cell-Selective Peptides via Phage Display and Next-Generation Sequencing

por Brinton, Lindsey T., Bauknight, Dustin K., Dasa, Siva Sai Krishna, Kelly, Kimberly A.
Publicado 2016

Large-Scale Drug Screen Identifies FDA-Approved Drugs for Repurposing in Sickle-Cell Disease

por Cannon, Matthew, Phillips, Hannah, Smith, Sidney, Williams, Katie, Brinton, Lindsey, Gregory, Charles, Landes, Kristina, Desai, Payal, Byrd, John, Lapalombella, Rosa
Publicado 2020

Cotargeting of XPO1 Enhances the Antileukemic Activity of Midostaurin and Gilteritinib in Acute Myeloid Leukemia

por Brinton, Lindsey T., Sher, Steven, Williams, Katie, Canfield, Daniel, Orwick, Shelley, Wasmuth, Ronni, Cempre, Casey, Skinner, Jordan, Lehman, Amy, Blachly, James S., Byrd, John C., Lapalombella, Rosa
Publicado 2020

A Bitter Taste Receptor as a Novel Molecular Target on Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma

por Hung, Jessica, Perez, Samantha M., Dasa, Siva Sai Krishna, Hall, Sarah P., Heckert, Danielle B., Murphy, Brian P., Crawford, Howard C., Kelly, Kimberly A., Brinton, Lindsey T.
Publicado 2023

Synergistic effect of BCL2 and FLT3 co-inhibition in acute myeloid leukemia

por Brinton, Lindsey T., Zhang, Pu, Williams, Katie, Canfield, Daniel, Orwick, Shelley, Sher, Steven, Wasmuth, Ronni, Beaver, Larry, Cempre, Casey, Skinner, Jordan, Cannon, Matthew, Govande, Mukul, Harrington, Bonnie, Lehman, Amy, Byrd, John C., Lapalombella, Rosa, Blachly, James S.
Publicado 2020

Gilteritinib Inhibits Glutamine Uptake and Utilization in FLT3-ITD–Positive AML

por Zavorka Thomas, Megan E., Lu, Xiyuan, Talebi, Zahra, Jeon, Jae Yoon, Buelow, Daelynn R., Gibson, Alice A., Uddin, Muhammad Erfan, Brinton, Lindsey T., Nguyen, Julie, Collins, Meghan, Lodi, Alessia, Sweeney, Shannon R., Campbell, Moray J., Sweet, Douglas H., Sparreboom, Alex, Lapalombella, Rosa, Tiziani, Stefano, Baker, Sharyn D.
Publicado 2021

Targeting OXPHOS de novo purine synthesis as the nexus of FLT3 inhibitor–mediated synergistic antileukemic actions

por Zhang, Pu, Brinton, Lindsey T., Gharghabi, Mehdi, Sher, Steven, Williams, Katie, Cannon, Matthew, Walker, Janek S., Canfield, Daniel, Beaver, Larry, Cempre, Casey B., Phillips, Hannah, Chen, Xuyong, Yan, Pearlly, Lehman, Amy, Scherle, Peggy, Wang, Min, Vaddi, Kris, Baiocchi, Robert, Wang, Ruoning, Sampath, Deepa, Alinari, Lapo, Blachly, James S., Lapalombella, Rosa
Publicado 2022

TP-0903 is active in models of drug-resistant acute myeloid leukemia

por Jeon, Jae Yoon, Buelow, Daelynn R., Garrison, Dominique A., Niu, Mingshan, Eisenmann, Eric D., Huang, Kevin M., Zavorka Thomas, Megan E., Weber, Robert H., Whatcott, Clifford J., Warner, Steve L., Orwick, Shelley J., Carmichael, Bridget, Stahl, Emily, Brinton, Lindsey T., Lapalombella, Rosa, Blachly, James S., Hertlein, Erin, Byrd, John C., Bhatnagar, Bhavana, Baker, Sharyn D.
Publicado 2020

Dysregulation of PRMT5 in chronic lymphocytic leukemia promotes progression with high risk of Richter’s transformation

por Hing, Zachary A., Walker, Janek S., Whipp, Ethan C., Brinton, Lindsey, Cannon, Matthew, Zhang, Pu, Sher, Steven, Cempre, Casey B., Brown, Fiona, Smith, Porsha L., Agostinelli, Claudio, Pileri, Stefano A., Skinner, Jordan N., Williams, Katie, Phillips, Hannah, Shaffer, Jami, Beaver, Larry P., Pan, Alexander, Shin, Kyle, Gregory, Charles T., Ozer, Gulcin H., Yilmaz, Selen A., Harrington, Bonnie K., Lehman, Amy M., Yu, Lianbo, Coppola, Vincenzo, Yan, Pearlly, Scherle, Peggy, Wang, Min, Pitis, Philip, Xu, Chaoyi, Vaddi, Kris, Chen-Kiang, Selina, Woyach, Jennifer, Blachly, James S., Alinari, Lapo, Yang, Yiping, Byrd, John C., Baiocchi, Robert A., Blaser, Bradley W., Lapalombella, Rosa
Publicado 2023