The Evolving Landscape of Neurotoxicity by Unconjugated Bilirubin: Role of Glial Cells and Inflammation

por Brites, Dora
Publicado 2012

Neuroinflammation and Depression: Microglia Activation, Extracellular Microvesicles and microRNA Dysregulation

por Brites, Dora, Fernandes, Adelaide
Publicado 2015

Microglia centered pathogenesis in ALS: insights in cell interconnectivity

por Brites, Dora, Vaz, Ana R.
Publicado 2014

S100B Impairs Oligodendrogenesis and Myelin Repair Following Demyelination Through RAGE Engagement

por Santos, Gisela, Barateiro, Andreia, Brites, Dora, Fernandes, Adelaide
Publicado 2020

Protective Signature of IFNγ-Stimulated Microglia Relies on miR-124-3p Regulation From the Secretome Released by Mutant APP Swedish Neuronal Cells

por Garcia, Gonçalo, Fernandes, Adelaide, Stein, Frank, Brites, Dora
Publicado 2022

Exploring New Inflammatory Biomarkers and Pathways during LPS-Induced M1 Polarization

por Cunha, Carolina, Gomes, Cátia, Vaz, Ana Rita, Brites, Dora
Publicado 2016

Synaptic Failure: Focus in an Integrative View of ALS

por Casas, Caty, Manzano, Raquel, Vaz, Rita, Osta, Rosario, Brites, Dora
Publicado 2016

Exosomes from NSC-34 Cells Transfected with hSOD1-G93A Are Enriched in miR-124 and Drive Alterations in Microglia Phenotype

por Pinto, Sara, Cunha, Carolina, Barbosa, Marta, Vaz, Ana R., Brites, Dora
Publicado 2017

Challenges in the Development of Drug Delivery Systems Based on Small Extracellular Vesicles for Therapy of Brain Diseases

por Loch-Neckel, Gecioni, Matos, Ana Teresa, Vaz, Ana Rita, Brites, Dora
Publicado 2022

Microglia Susceptibility to Free Bilirubin Is Age-Dependent

por Vaz, Ana Rita, Falcão, Ana Sofia, Scarpa, Eleonora, Semproni, Carlotta, Brites, Dora
Publicado 2020

Neuronal Dynamics and miRNA Signaling Differ between SH-SY5Y APPSwe and PSEN1 Mutant iPSC-Derived AD Models upon Modulation with miR-124 Mimic and Inhibitor

por Garcia, Gonçalo, Pinto, Sara, Cunha, Mar, Fernandes, Adelaide, Koistinaho, Jari, Brites, Dora
Publicado 2021

Differences in Immune-Related Genes Underlie Temporal and Regional Pathological Progression in 3xTg-AD Mice

por Fernandes, Adelaide, Caldeira, Cláudia, Cunha, Carolina, Ferreiro, Elisabete, Vaz, Ana Rita, Brites, Dora
Publicado 2022

Time-dependent dual effects of high levels of unconjugated bilirubin on the human blood-brain barrier lining

por Palmela, Inês, Sasaki, Hiroyuki, Cardoso, Filipa L., Moutinho, Miguel, Kim, Kwang S., Brites, Dora, Brito, Maria A.
Publicado 2012

Microglia change from a reactive to an age-like phenotype with the time in culture

por Caldeira, Cláudia, Oliveira, Ana F., Cunha, Carolina, Vaz, Ana R., Falcão, Ana S., Fernandes, Adelaide, Brites, Dora
Publicado 2014

Phenotypic Effects of Wild-Type and Mutant SOD1 Expression in N9 Murine Microglia at Steady State, Inflammatory and Immunomodulatory Conditions

por Vaz, Ana Rita, Pinto, Sara, Ezequiel, Catarina, Cunha, Carolina, Carvalho, Luís A., Moreira, Rui, Brites, Dora
Publicado 2019

Hydrophilic bile acids protect human blood-brain barrier endothelial cells from disruption by unconjugated bilirubin: an in vitro study

por Palmela, Inês, Correia, Leonor, Silva, Rui F. M., Sasaki, Hiroyuki, Kim, Kwang S., Brites, Dora, Brito, Maria A.
Publicado 2015

Key Aging-Associated Alterations in Primary Microglia Response to Beta-Amyloid Stimulation

por Caldeira, Cláudia, Cunha, Carolina, Vaz, Ana R., Falcão, Ana S., Barateiro, Andreia, Seixas, Elsa, Fernandes, Adelaide, Brites, Dora
Publicado 2017

Overexpression of miR-124 in Motor Neurons Plays a Key Role in ALS Pathological Processes

por Vaz, Ana Rita, Vizinha, Daniela, Morais, Hermes, Colaço, Ana Rita, Loch-Neckel, Gecioni, Barbosa, Marta, Brites, Dora
Publicado 2021

Intrathecal Injection of the Secretome from ALS Motor Neurons Regulated for miR-124 Expression Prevents Disease Outcomes in SOD1-G93A Mice

por Barbosa, Marta, Santos, Marta, de Sousa, Nídia, Duarte-Silva, Sara, Vaz, Ana Rita, Salgado, António J., Brites, Dora
Publicado 2022

Exposure to Lipopolysaccharide and/or Unconjugated Bilirubin Impair the Integrity and Function of Brain Microvascular Endothelial Cells

por Cardoso, Filipa L., Kittel, Ágnes, Veszelka, Szilvia, Palmela, Inês, Tóth, Andrea, Brites, Dora, Deli, Mária A., Brito, Maria A.
Publicado 2012