Amyloid Disassembly: What Can We Learn from Chaperones?

por Almeida, Zaida L., Brito, Rui M. M.
Publicado 2022

The Therapeutic Prospects of Targeting IL-1R1 for the Modulation of Neuroinflammation in Central Nervous System Disorders

por Luís, João P., Simões, Carlos J. V., Brito, Rui M. M.
Publicado 2022

The Central Role of Non-Structural Protein 1 (NS1) in Influenza Biology and Infection

por Rosário-Ferreira, Nícia, Preto, António J., Melo, Rita, Moreira, Irina S., Brito, Rui M. M.
Publicado 2020

Conformational Dynamics of the Soluble and Membrane-Bound Forms of Interleukin-1 Receptor Type-1: Insights into Linker Flexibility and Domain Orientation

por Luís, João P., Mata, Ana I., Simões, Carlos J. V., Brito, Rui M. M.
Publicado 2022

Unveiling New Druggable Pockets in Influenza Non-Structural Protein 1: NS1–Host Interactions as Antiviral Targets for Flu

por Cunha, Andreia E. S., Loureiro, Rui J. S., Simões, Carlos J. V., Brito, Rui M. M.
Publicado 2023

Oligomerization Profile of Human Transthyretin Variants with Distinct Amyloidogenicity

por Frangolho, Ana, Correia, Bruno E., Vaz, Daniela C., Almeida, Zaida L., Brito, Rui M. M.
Publicado 2020

Changes in Channel Trafficking and Protein Stability Caused by LQT2 Mutations in the PAS Domain of the HERG Channel

por Harley, Carol A., Jesus, Catarina S. H., Carvalho, Ricardo, Brito, Rui M. M., Morais-Cabral, João H.
Publicado 2012

A New Folding Kinetic Mechanism for Human Transthyretin and the Influence of the Amyloidogenic V30M Mutation

por Jesus, Catarina S. H., Almeida, Zaida L., Vaz, Daniela C., Faria, Tiago Q., Brito, Rui M. M.
Publicado 2016

An Innovative Sequence-to-Structure-Based Approach to Drug Resistance Interpretation and Prediction: The Use of Molecular Interaction Fields to Detect HIV-1 Protease Binding-Site D...

por Alves, Nuno G., Mata, Ana I., Luís, João P., Brito, Rui M. M., Simões, Carlos J. V.
Publicado 2020

Modeling of the Toll-like receptor 3 and a putative Toll-like receptor 3 antagonist encoded by the African swine fever virus

por Henriques, Elsa S, Brito, Rui M M, Soares, Hugo, Ventura, Sónia, de Oliveira, Vivian L, Parkhouse, R Michael E
Publicado 2011

Searching for the Best Transthyretin Aggregation Protocol to Study Amyloid Fibril Disruption

por Ferreira, Elisabete, Almeida, Zaida L., Cruz, Pedro F., Silva e Sousa, Marta, Veríssimo, Paula, Brito, Rui M. M.
Publicado 2021

Ligand-Targeted Delivery of Photosensitizers for Cancer Treatment

por Gierlich, Piotr, Mata, Ana I., Donohoe, Claire, Brito, Rui M. M., Senge, Mathias O., Gomes-da-Silva, Lígia C.
Publicado 2020

Correction to: Designing optimized drug candidates with Generative Adversarial Network

por Abbasi, Maryam, Santos, Beatriz P., Pereira, Tiago C., Sofa, Raul, Monteiro, Nelson R. C., Simões, Carlos J. V., Brito, Rui M. M., Ribeiro, Bernardete, Oliveira, José L., Arrais, Joel P.
Publicado 2022

Alchemical Design of Pharmacological Chaperones with Higher Affinity for Phenylalanine Hydroxylase

por Conde-Giménez, María, Galano-Frutos, Juan José, Galiana-Cameo, María, Mahía, Alejandro, Victor, Bruno L., Salillas, Sandra, Velázquez-Campoy, Adrián, Brito, Rui M. M., Gálvez, José Antonio, Díaz-de-Villegas, María D., Sancho, Javier
Publicado 2022