Moving metabolomics from a data-driven science to an integrative systems science

por Reinke, Stacey N, Broadhurst, David I
Publicado 2012

Translational biomarker discovery in clinical metabolomics: an introductory tutorial

por Xia, Jianguo, Broadhurst, David I., Wilson, Michael, Wishart, David S.
Publicado 2012

A comparative evaluation of the generalised predictive ability of eight machine learning algorithms across ten clinical metabolomics data sets for binary classification

por Mendez, Kevin M., Reinke, Stacey N., Broadhurst, David I.
Publicado 2019

Migrating from partial least squares discriminant analysis to artificial neural networks: a comparison of functionally equivalent visualisation and feature contribution tools using...

por Mendez, Kevin M., Broadhurst, David I., Reinke, Stacey N.
Publicado 2020

Toward collaborative open data science in metabolomics using Jupyter Notebooks and cloud computing

por Mendez, Kevin M., Pritchard, Leighton, Reinke, Stacey N., Broadhurst, David I.
Publicado 2019

Direct infusion mass spectrometry metabolomics dataset: a benchmark for data processing and quality control

por Kirwan, Jennifer A, Weber, Ralf J M, Broadhurst, David I, Viant, Mark R
Publicado 2014

Functional Genomics Via Metabolic Footprinting: Monitoring Metabolite Secretion by Escherichia Coli Tryptophan Metabolism Mutants Using FT–IR and Direct Injection Electrospray Mass...

por Kaderbhai, Naheed N., Broadhurst, David I., Ellis, David I., Goodacre, Royston, Kell, Douglas B.
Publicado 2003

Metabolomics reveals mouse plasma metabolite responses to acute exercise and effects of disrupting AMPK-glycogen interactions

por Belhaj, Mehdi R., Lawler, Nathan G., Hawley, John A., Broadhurst, David I., Hoffman, Nolan J., Reinke, Stacey N.
Publicado 2022

The Metabolomic Profile of Umbilical Cord Blood in Neonatal Hypoxic Ischaemic Encephalopathy

por Walsh, Brian H., Broadhurst, David I., Mandal, Rupasri, Wishart, David S., Boylan, Geraldine B., Kenny, Louise C., Murray, Deirdre M.
Publicado 2012

Detecting Sex-Related Changes to the Metabolome of a Critically Endangered Freshwater Crayfish During the Mating Season

por Lette, Emily D., Burnham, Quinton F., Lawler, Nathan, Horwitz, Pierre, Boyce, Mary C., Broadhurst, David I., Duffy, Rodney, Koenders, Annette
Publicado 2021

Rapid inflammasome activation in microglia contributes to brain disease in HIV/AIDS

por Walsh, John G, Reinke, Stacey N, Mamik, Manmeet K, McKenzie, Brienne A, Maingat, Ferdinand, Branton, William G, Broadhurst, David I, Power, Christopher
Publicado 2014

Evidence That Multiple Defects in Lipid Regulation Occur before Hyperglycemia during the Prodrome of Type-2 Diabetes

por Anderson, Simon G., Dunn, Warwick B., Banerjee, Moulinath, Brown, Marie, Broadhurst, David I., Goodacre, Royston, Cooper, Garth J. S., Kell, Douglas B., Cruickshank, J. Kennedy
Publicado 2014

Sildenafil Therapy Normalizes the Aberrant Metabolomic Profile in the Comt(−/−) Mouse Model of Preeclampsia/Fetal Growth Restriction

por Stanley, Joanna L., Sulek, Karolina, Andersson, Irene J., Davidge, Sandra T., Kenny, Louise C., Sibley, Colin P., Mandal, Rupasri, Wishart, David S., Broadhurst, David I., Baker, Philip N.
Publicado 2015

OnPLS-Based Multi-Block Data Integration: A Multivariate Approach to Interrogating Biological Interactions in Asthma

por Reinke, Stacey N., Galindo-Prieto, Beatriz, Skotare, Tomas, Broadhurst, David I., Singhania, Akul, Horowitz, Daniel, Djukanović, Ratko, Hinks, Timothy S.C., Geladi, Paul, Trygg, Johan, Wheelock, Craig E.
Publicado 2018

Lipopolysaccharide-induced interferon response networks at birth are predictive of severe viral lower respiratory infections in the first year of life

por Read, James F., Serralha, Michael, Mok, Danny, Holt, Barbara J., Cruickshank, Mark, Karpievitch, Yuliya V., Broadhurst, David I., Sly, Peter D., Strickland, Deborah H., Reinke, Stacey N., Holt, Patrick G., Bosco, Anthony
Publicado 2022

Metabolomics enables precision medicine: “A White Paper, Community Perspective”

por Beger, Richard D., Dunn, Warwick, Schmidt, Michael A., Gross, Steven S., Kirwan, Jennifer A., Cascante, Marta, Brennan, Lorraine, Wishart, David S., Oresic, Matej, Hankemeier, Thomas, Broadhurst, David I., Lane, Andrew N., Suhre, Karsten, Kastenmüller, Gabi, Sumner, Susan J., Thiele, Ines, Fiehn, Oliver, Kaddurah-Daouk, Rima
Publicado 2016

Kynurenic acid underlies sex-specific immune responses to COVID-19

por Cai, Yuping, Kim, Daniel J., Takahashi, Takehiro, Broadhurst, David I., Ma, Shuangge, Rattray, Nicholas J.W., Casanovas-Massana, Arnau, Israelow, Benjamin, Klein, Jon, Lucas, Carolina, Mao, Tianyang, Moore, Adam J., Muenker, M. Catherine, Oh, Jieun, Silva, Julio, Wong, Patrick, Ko, Albert I., Khan, Sajid A., Iwasaki, Akiko, Johnson, Caroline H.
Publicado 2020

Kynurenic acid may underlie sex-specific immune responses to COVID-19

por Cai, Yuping, Kim, Daniel J., Takahashi, Takehiro, Broadhurst, David I., Yan, Hong, Ma, Shuangge, Rattray, Nicholas J. W., Casanovas-Massana, Arnau, Israelow, Benjamin, Klein, Jon, Lucas, Carolina, Mao, Tianyang, Moore, Adam J., Muenker, M. Catherine, Oh, Ji Eun, Silva, Julio, Wong, Patrick, Ko, Albert I., Khan, Sajid A., Iwasaki, Akiko, Johnson, Caroline H.
Publicado 2021

Urinary metabotype of severe asthma evidences decreased carnitine metabolism independent of oral corticosteroid treatment in the U-BIOPRED study

por Reinke, Stacey N., Naz, Shama, Chaleckis, Romanas, Gallart-Ayala, Hector, Kolmert, Johan, Kermani, Nazanin Z., Tiotiu, Angelica, Broadhurst, David I., Lundqvist, Anders, Olsson, Henric, Ström, Marika, Wheelock, Åsa M., Gómez, Cristina, Ericsson, Magnus, Sousa, Ana R., Riley, John H., Bates, Stewart, Scholfield, James, Loza, Matthew, Baribaud, Frédéric, Bakke, Per S., Caruso, Massimo, Chanez, Pascal, Fowler, Stephen J., Geiser, Thomas, Howarth, Peter, Horváth, Ildikó, Krug, Norbert, Montuschi, Paolo, Behndig, Annelie, Singer, Florian, Musial, Jacek, Shaw, Dominick E., Dahlén, Barbro, Hu, Sile, Lasky-Su, Jessica, Sterk, Peter J., Chung, Kian Fan, Djukanovic, Ratko, Dahlén, Sven-Erik, Adcock, Ian M., Wheelock, Craig E.
Publicado 2022