Nucleic acid-based vaccines targeting respiratory syncytial virus: Delivering the goods

por Smith, Trevor R. F., Schultheis, Katherine, Broderick, Kate E.
Publicado 2017

Characterization of guinea pig T cell responses elicited after EP-assisted delivery of DNA vaccines to the skin

por Schultheis, Katherine, Schaefer, Hubert, Yung, Bryan S., Oh, Janet, Muthumani, Karuppiah, Humeau, Laurent, Broderick, Kate E., Smith, Trevor R.F.
Publicado 2016

Optimized In Vivo Transfer of Small Interfering RNA Targeting Dermal Tissue Using In Vivo Surface Electroporation

por Broderick, Kate E, Chan, Amy, Lin, Feng, Shen, Xuefei, Kichaev, Gleb, Khan, Amir S, Aubin, Justin, Zimmermann, Tracy S, Sardesai, Niranjan Y.
Publicado 2012

Enhanced Delivery and Potency of Self-Amplifying mRNA Vaccines by Electroporation in Situ

por Cu, Yen, Broderick, Kate E., Banerjee, Kaustuv, Hickman, Julie, Otten, Gillis, Barnett, Susan, Kichaev, Gleb, Sardesai, Niranjan Y., Ulmer, Jeffrey B., Geall, Andrew
Publicado 2013

Protection against dengue disease by synthetic nucleic acid antibody prophylaxis/immunotherapy

por Flingai, Seleeke, Plummer, Emily M., Patel, Ami, Shresta, Sujan, Mendoza, Janess M., Broderick, Kate E., Sardesai, Niranjan Y., Muthumani, Kar, Weiner, David B.
Publicado 2015

A multi-head intradermal electroporation device allows for tailored and increased dose DNA vaccine delivery to the skin

por McCoy, Jay R, Mendoza, Janess M, Spik, Kristin W, Badger, Catherine, Gomez, Alan F, Schmaljohn, Connie S, Sardesai, Niranjan Y, Broderick, Kate E
Publicado 2014

Active Immunoprophylaxis and Vaccine Augmentations Mediated by a Novel Plasmid DNA Formulation

por Schommer, Nina N., Nguyen, Jacklyn, Yung, Bryan S., Schultheis, Katherine, Muthumani, Kar, Weiner, David B., Humeau, Laurent, Broderick, Kate E., Smith, Trevor R.F.
Publicado 2019

Elucidating the Kinetics of Expression and Immune Cell Infiltration Resulting from Plasmid Gene Delivery Enhanced by Surface Dermal Electroporation

por Mendoza, Janess M., Amante, Dinah H., Kichaev, Gleb, Knott, Christine L., Kiosses, William B., Smith, Trevor R. F., Sardesai, Niranjan Y., Broderick, Kate E.
Publicado 2013

Immunogenicity of a protective intradermal DNA vaccine against lassa virus in cynomolgus macaques

por Jiang, Jingjing, Banglore, Preeti, Cashman, Kathleen A., Schmaljohn, Connie S., Schultheis, Katherine, Pugh, Holly, Nguyen, Jacklyn, Humeau, Laurent M., Broderick, Kate E., Ramos, Stephanie J.
Publicado 2019

DNA vaccines elicit durable protective immunity against individual or simultaneous infections with Lassa and Ebola viruses in guinea pigs

por Cashman, Kathleen A., Wilkinson, Eric R., Wollen, Suzanne E., Shamblin, Joshua D., Zelko, Justine M., Bearss, Jeremy J., Zeng, Xiankun, Broderick, Kate E., Schmaljohn, Connie S.
Publicado 2017

Gag and env conserved element CE DNA vaccines elicit broad cytotoxic T cell responses targeting subdominant epitopes of HIV and SIV Able to recognize virus-infected cells in macaqu...

por Hu, Xintao, Lu, Zhongyan, Valentin, Antonio, Rosati, Margherita, Broderick, Kate E., Sardesai, Niranjan Y., Marx, Preston A., Mullins, James I., Pavlakis, George N., Felber, Barbara K.
Publicado 2018

A Heterologous Prime/Boost Vaccination Strategy Enhances the Immunogenicity of Therapeutic Vaccines for Hepatitis C Virus

por Fournillier, Anne, Frelin, Lars, Jacquier, Emilie, Ahlén, Gustaf, Brass, Anette, Gerossier, Estelle, Holmström, Fredrik, Broderick, Kate E., Sardesai, Niranjan Y., Bonnefoy, Jean-Yves, Inchauspé, Geneviève, Sällberg, Matti
Publicado 2013

DNA vaccination strategy targets epidermal dendritic cells, initiating their migration and induction of a host immune response

por Smith, Trevor RF, Schultheis, Katherine, Kiosses, William B, Amante, Dinah H, Mendoza, Janess M, Stone, John C, McCoy, Jay R, Sardesai, Niranjan Y, Broderick, Kate E
Publicado 2014

Adjuvant Screen Identifies Synthetic DNA-Encoding Flt3L and CD80 Immunotherapeutics as Candidates for Enhancing Anti-tumor T Cell Responses

por Thorne, Amy Haseley, Malo, Kirsten N., Wong, Ashley J., Nguyen, Tricia T., Cooch, Neil, Reed, Charles, Yan, Jian, Broderick, Kate E., Smith, Trevor R. F., Masteller, Emma L., Humeau, Laurent
Publicado 2020

Immunotherapy with DNA vaccine and live attenuated rubella/SIV gag vectors plus early ART can prevent SIVmac251 viral rebound in acutely infected rhesus macaques

por Virnik, Konstantin, Rosati, Margherita, Medvedev, Alexei, Scanlan, Aaron, Walsh, Gabrielle, Dayton, Frances, Broderick, Kate E., Lewis, Mark, Bryson, Yvonne, Lifson, Jeffrey D., Ruprecht, Ruth M., Felber, Barbara K., Berkower, Ira
Publicado 2020

Live Virus Neutralisation of the 501Y.V1 and 501Y.V2 SARS-CoV-2 Variants following INO-4800 Vaccination of Ferrets

por Riddell, Shane, Goldie, Sarah, McAuley, Alexander J., Kuiper, Michael J., Durr, Peter A., Blasdell, Kim R., Tachedjian, Mary, Druce, Julian D., Smith, Trevor R. F., Broderick, Kate E., Vasan, Seshadri S.
Publicado 2021

Enhanced Efficacy of a Codon-Optimized DNA Vaccine Encoding the Glycoprotein Precursor Gene of Lassa Virus in a Guinea Pig Disease Model When Delivered by Dermal Electroporation

por Cashman, Kathleen A., Broderick, Kate E., Wilkinson, Eric R., Shaia, Carl I., Bell, Todd M., Shurtleff, Amy C., Spik, Kristin W., Badger, Catherine V., Guttieri, Mary C., Sardesai, Niranjan Y., Schmaljohn, Connie S.
Publicado 2013

HIV Env conserved element DNA vaccine alters immunodominance in macaques

por Hu, Xintao, Valentin, Antonio, Rosati, Margherita, Manocheewa, Siriphan, Alicea, Candido, Chowdhury, Bhabadeb, Bear, Jenifer, Broderick, Kate E., Sardesai, Niranjan Y., Gall, Sylvie Le, Mullins, James I., Pavlakis, George N., Felber, Barbara K.
Publicado 2017

A DNA vaccine delivered by dermal electroporation fully protects cynomolgus macaques against Lassa fever

por Cashman, Kathleen A., Wilkinson, Eric R., Shaia, Carl I., Facemire, Paul R., Bell, Todd M., Bearss, Jeremy J., Shamblin, Joshua D., Wollen, Suzanne E., Broderick, Kate E., Sardesai, Niranjan Y., Schmaljohn, Connie S.
Publicado 2017

HIV-1 Env DNA Vaccine plus Protein Boost Delivered by EP Expands B- and T-Cell Responses and Neutralizing Phenotype In Vivo

por Muthumani, Kar, Wise, Megan C., Broderick, Kate E., Hutnick, Natalie, Goodman, Jonathan, Flingai, Seleeke, Yan, Jian, Bian, Chaoran B., Mendoza, Janess, Tingey, Colleen, Wilson, Christine, Wojtak, Krzysztof, Sardesai, Niranjan Y., Weiner, David B.
Publicado 2013