Tuberous Sclerosis Complex as Disease Model for Investigating mTOR-Related Gliopathy During Epileptogenesis

por Zimmer, Till S., Broekaart, Diede W. M., Gruber, Victoria-Elisabeth, van Vliet, Erwin A., Mühlebner, Angelika, Aronica, Eleonora
Publicado 2020

Altered Extracellular Matrix as an Alternative Risk Factor for Epileptogenicity in Brain Tumors

por de Jong, Jody M., Broekaart, Diede W. M., Bongaarts, Anika, Mühlebner, Angelika, Mills, James D., van Vliet, Erwin A., Aronica, Eleonora
Publicado 2022

Increased expression of matrix metalloproteinase 3 can be attenuated by inhibition of microRNA-155 in cultured human astrocytes

por Korotkov, Anatoly, Broekaart, Diede W. M., van Scheppingen, Jackelien, Anink, Jasper J., Baayen, Johannes C., Idema, Sander, Gorter, Jan A., Aronica, Eleonora, van Vliet, Erwin A.
Publicado 2018

The Gelatinase Inhibitor ACT-03 Reduces Gliosis in the Rapid Kindling Rat Model of Epilepsy, and Attenuates Inflammation and Loss of Barrier Integrity In Vitro

por Broekaart, Diede W. M., Zimmer, Till S., Cohen, Sophie T., Tessers, Rianne, Anink, Jasper J., de Vries, Helga E., Gorter, Jan A., Prades, Roger, Aronica, Eleonora, van Vliet, Erwin A.
Publicado 2022

microRNA‐132 is overexpressed in glia in temporal lobe epilepsy and reduces the expression of pro‐epileptogenic factors in human cultured astrocytes

por Korotkov, Anatoly, Broekaart, Diede W. M., Banchaewa, Leyla, Pustjens, Ben, van Scheppingen, Jackelien, Anink, Jasper J., Baayen, Johannes C., Idema, Sander, Gorter, Jan A., van Vliet, Erwin A., Aronica, Eleonora
Publicado 2019

Increased expression of miR142 and miR155 in glial and immune cells after traumatic brain injury may contribute to neuroinflammation via astrocyte activation

por Korotkov, Anatoly, Puhakka, Noora, Gupta, Shalini Das, Vuokila, Niina, Broekaart, Diede W. M., Anink, Jasper J., Heiskanen, Mette, Karttunen, Jenni, van Scheppingen, Jackelien, Huitinga, Inge, Mills, James D., van Vliet, Erwin A., Pitkänen, Asla, Aronica, Eleonora
Publicado 2020

Balloon cells promote immune system activation in focal cortical dysplasia type 2b

por Zimmer, Till S., Broekaart, Diede W. M., Luinenburg, Mark, Mijnsbergen, Caroline, Anink, Jasper J., Sim, Nam Suk, Michailidou, Iliana, Jansen, Floor E., van Rijen, Peter C., Lee, Jeong Ho, François, Liesbeth, van Eyll, Jonathan, Dedeurwaerdere, Stefanie, van Vliet, Erwin A., Mühlebner, Angelika, Mills, James D., Aronica, Eleonora
Publicado 2021

Seizure-mediated iron accumulation and dysregulated iron metabolism after status epilepticus and in temporal lobe epilepsy

por Zimmer, Till S., David, Bastian, Broekaart, Diede W. M., Schidlowski, Martin, Ruffolo, Gabriele, Korotkov, Anatoly, van der Wel, Nicole N., van Rijen, Peter C., Mühlebner, Angelika, van Hecke, Wim, Baayen, Johannes C., Idema, Sander, François, Liesbeth, van Eyll, Jonathan, Dedeurwaerdere, Stefanie, Kessels, Helmut W., Surges, Rainer, Rüber, Theodor, Gorter, Jan A., Mills, James D., van Vliet, Erwin A., Aronica, Eleonora
Publicado 2021

Down-regulation of the brain-specific cell-adhesion molecule contactin-3 in tuberous sclerosis complex during the early postnatal period

por Korotkov, Anatoly, Luinenburg, Mark J., Romagnolo, Alessia, Zimmer, Till S., van Scheppingen, Jackelien, Bongaarts, Anika, Broekaart, Diede W. M., Anink, Jasper J., Mijnsbergen, Caroline, Jansen, Floor E., van Hecke, Wim, Spliet, Wim G., van Rijen, Peter C., Feucht, Martha, Hainfellner, Johannes A., Krsek, Pavel, Zamecnik, Josef, Crino, Peter B., Kotulska, Katarzyna, Lagae, Lieven, Jansen, Anna C., Kwiatkowski, David J., Jozwiak, Sergiusz, Curatolo, Paolo, Mühlebner, Angelika, van Vliet, Erwin A., Mills, James D., Aronica, Eleonora
Publicado 2022

Dysregulation of the MMP/TIMP Proteolytic System in Subependymal Giant Cell Astrocytomas in Patients With Tuberous Sclerosis Complex: Modulation of MMP by MicroRNA-320d In Vitro

por Bongaarts, Anika, de Jong, Jody M, Broekaart, Diede W M, van Scheppingen, Jackelien, Anink, Jasper J, Mijnsbergen, Caroline, Jansen, Floor E, Spliet, Wim G M, den Dunnen, Wilfred F A, Gruber, Victoria E, Scholl, Theresa, Hainfellner, Johannes A, Feucht, Martha, Borkowska, Julita, Kotulska, Katarzyna, Jozwiak, Sergiusz, Grajkowska, Wieslawa, Buccoliero, Anna Maria, Caporalini, Chiara, Giordano, Flavio, Genitori, Lorenzo, Scicluna, Brendon P, Schouten-van Meeteren, Antoinette Y N, van Vliet, Erwin A, Mühlebner, Angelika, Mills, James D, Aronica, Eleonora
Publicado 2020

MicroRNA‐34a activation in tuberous sclerosis complex during early brain development may lead to impaired corticogenesis

por Korotkov, Anatoly, Sim, Nam Suk, Luinenburg, Mark J., Anink, Jasper J., van Scheppingen, Jackelien, Zimmer, Till S., Bongaarts, Anika, Broekaart, Diede W. M., Mijnsbergen, Caroline, Jansen, Floor E., Van Hecke, Wim, Spliet, Wim G. M., van Rijen, Peter C., Feucht, Martha, Hainfellner, Johannes A., Kršek, Pavel, Zamecnik, Josef, Crino, Peter B., Kotulska, Katarzyna, Lagae, Lieven, Jansen, Anna C., Kwiatkowski, David J., Jozwiak, Sergiusz, Curatolo, Paolo, Mühlebner, Angelika, Lee, Jeong H., Mills, James D., van Vliet, Erwin A., Aronica, Eleonora
Publicado 2021