Genetics of Systemic Sclerosis: An Update

por Broen, Jasper C. A., Coenen, Marieke J. H., Radstake, Timothy R. D. J.
Publicado 2011

MicroRNAs underlie plasmacytoid dentritic cell dysfunction in systemic sclerosis

por Broen, Jasper C, van Bon, Lenny, Rossen, Nick P, Rossato, Marzia, Radstake, Timothy RDJ
Publicado 2012

Quantification of Double Stranded DNA Breaks and Telomere Length as Proxies for Corneal Damage and Replicative Stress in Human Keratoconus Corneas

por Wisse, Robert P. L., Kuiper, Jonas J. W., Radstake, Timothy R. D., Broen, Jasper C. A.
Publicado 2019

Telomere biology is differently affected within clinical subsets of systemic sclerosis and points towards different downstream defects

por Broen, Jasper CA, McGlynn, Liane, Chee, Meng May, Geurts-van Bon, Lenny, Lafyatis, Robert L, Radstake, Timothy RDJ, Shiels, Paul G
Publicado 2012

The Pronounced Th17 Profile in Systemic Sclerosis (SSc) Together with Intracellular Expression of TGFβ and IFNγ Distinguishes SSc Phenotypes

por Radstake, Timothy R. D. J., van Bon, Lenny, Broen, Jasper, Hussiani, Anila, Hesselstrand, Roger, Wuttge, Dirk M., Deng, Yanhui, Simms, Robbert, Lubberts, Erik, Lafyatis, Robert
Publicado 2009

Increased Frequency and Compromised Function of T Regulatory Cells in Systemic Sclerosis (SSc) Is Related to a Diminished CD69 and TGFβ Expression

por Radstake, Timothy R. D. J., van Bon, Lenny, Broen, Jasper, Wenink, Mark, Santegoets, Kim, Deng, Yanhui, Hussaini, Anila, Simms, Robert, Cruikshank, William W., Lafyatis, Robert
Publicado 2009

Treat-to-target in rheumatoid arthritis: a real-world study of the application and impact of treat-to-target within the wider context of patient management, patient centricity and...

por Taylor, Peter C., Fautrel, Bruno, Piette, Yves, Romero-Yuste, Susana, Broen, Jasper, Welcker, Martin, Howell, Oliver, Rottier, Elke, Zignani, Monia, Van Beneden, Katrien, Caporali, Roberto, Alten, Rieke
Publicado 2022

Increased mTORC1 activation in salivary gland B cells and T cells from patients with Sjögren’s syndrome: mTOR inhibition as a novel therapeutic strategy to halt immunopathology?

por Blokland, Sofie L M, Hillen, Maarten R, Wichers, Catharina G K, Zimmermann, Maili, Kruize, Aike A, Radstake, Timothy R D J, Broen, Jasper C A, van Roon, Joel A G
Publicado 2019

Aberrant leukocyte telomere length in Birdshot Uveitis

por Vazirpanah, Nadia, Verhagen, Fleurieke H., Rothova, Anna, Missotten, Tom O. A. R., van Velthoven, Mirjam, Den Hollander, Anneke I., Hoyng, Carel B., Radstake, Timothy.R. D. J., Broen, Jasper C. A., Kuiper, Jonas J. W.
Publicado 2017

A rare polymorphism in Toll Like Receptor 2 is associated with systemic sclerosis phenotype and increases production of inflammatory mediators

por Broen, Jasper CA, Bossini-Castillo, Lara, Bon, Lenny van, Vonk, Madelon C, Knaapen, Hanneke, Beretta, Lorenzo, Rueda, Blanca, Hesselstrand, Roger, Herrick, Ariane, Worthington, Jane, Hunzelmann, Nicholas, Denton, Christopher, Fonseca, Carmen, Riemekasten, Gabriela, Kiener, Hans, Scorza, Raffaella, Simeon, Carmen P, Ortego-Centeno, Norberto, Gonzalez-Gay, Miguel A, Airo’, Paolo, Coenen, Marieke JH, Martin, Javier, Radstake, Timothy RDJ
Publicado 2011

Analysis of the association between CD40 and CD40 ligand polymorphisms and systemic sclerosis

por Teruel, María, Simeon, Carmen P, Broen, Jasper, Vonk, Madelon C, Carreira, Patricia, Camps, Maria Teresa, García-Portales, Rosa, Delgado-Frías, Esmeralda, Gallego, Maria, Espinosa, Gerard, Beretta, Lorenzo, Airó, Paolo, Lunardi, Claudio, Riemekasten, Gabriela, Witte, Torsten, Krieg, Thomas, Kreuter, Alexander, Distler, Jörg HW, Hunzelmann, Nicolas, Koeleman, Bobby P, Voskuyl, Alexandre E, Schuerwegh, Annemie J, González-Gay, Miguel Ángel, Radstake, Timothy RDJ, Martin, Javier
Publicado 2012

KCNA5 gene is not confirmed as a systemic sclerosis-related pulmonary arterial hypertension genetic susceptibility factor

por Bossini-Castillo, Lara, Simeon, Carmen P, Beretta, Lorenzo, Broen, Jasper, Vonk, Madelon C, Callejas, José Luis, Carreira, Patricia, Rodríguez-Rodríguez, Luis, García-Portales, Rosa, González-Gay, Miguel A, Castellví, Ivan, Camps, María Teresa, Tolosa, Carlos, Vicente-Rabaneda, Esther, Egurbide, María Victoria, Schuerwegh, Annemie J, Hesselstrand, Roger, Lunardi, Claudio, van Laar, Jacob M, Shiels, Paul, Herrick, Ariane, Worthington, Jane, Denton, Christopher, Radstake, Timothy RDJ, Fonseca, Carmen, Martin, Javier
Publicado 2012

A multicenter study confirms CD226 gene association with systemic sclerosis-related pulmonary fibrosis

por Bossini-Castillo, Lara, Simeon, Carmen P, Beretta, Lorenzo, Broen, Jasper C, Vonk, Madelon C, Ríos-Fernández, Raquel, Espinosa, Gerard, Carreira, Patricia, Camps, María T, Castillo, Maria J, González-Gay, Miguel A, Beltrán, Emma, Carmen Freire, María del, Narváez, Javier, Tolosa, Carlos, Witte, Torsten, Kreuter, Alexander, Schuerwegh, Annemie J, Hoffmann-Vold, Anna-Maria, Hesselstrand, Roger, Lunardi, Claudio, van Laar, Jacob M, Chee, Meng May, Herrick, Ariane, Koeleman, Bobby PC, Denton, Christopher P, Fonseca, Carmen, Radstake, Timothy RDJ, Martin, Javier
Publicado 2012

Identification of Novel Genetic Markers Associated with Clinical Phenotypes of Systemic Sclerosis through a Genome-Wide Association Strategy

por Gorlova, Olga, Martin, Jose-Ezequiel, Rueda, Blanca, Koeleman, Bobby P. C., Ying, Jun, Teruel, Maria, Diaz-Gallo, Lina-Marcela, Broen, Jasper C., Vonk, Madelon C., Simeon, Carmen P., Alizadeh, Behrooz Z., Coenen, Marieke J. H., Voskuyl, Alexandre E., Schuerwegh, Annemie J., van Riel, Piet L. C. M., Vanthuyne, Marie, van 't Slot, Ruben, Italiaander, Annet, Ophoff, Roel A., Hunzelmann, Nicolas, Fonollosa, Vicente, Ortego-Centeno, Norberto, González-Gay, Miguel A., García-Hernández, Francisco J., González-Escribano, María F., Airo, Paolo, van Laar, Jacob, Worthington, Jane, Hesselstrand, Roger, Smith, Vanessa, de Keyser, Filip, Houssiau, Fredric, Chee, Meng May, Madhok, Rajan, Shiels, Paul G., Westhovens, Rene, Kreuter, Alexander, de Baere, Elfride, Witte, Torsten, Padyukov, Leonid, Nordin, Annika, Scorza, Raffaella, Lunardi, Claudio, Lie, Benedicte A., Hoffmann-Vold, Anna-Maria, Palm, Øyvind, García de la Peña, Paloma, Carreira, Patricia, Varga, John, Hinchcliff, Monique, Lee, Annette T., Gourh, Pravitt, Amos, Christopher I., Wigley, Frederick M., Hummers, Laura K., Hummers, J., Nelson, J. Lee, Riemekasten, Gabriella, Herrick, Ariane, Beretta, Lorenzo, Fonseca, Carmen, Denton, Christopher P., Gregersen, Peter K., Agarwal, Sandeep, Assassi, Shervin, Tan, Filemon K., Arnett, Frank C., Radstake, Timothy R. D. J., Mayes, Maureen D., Martin, Javier
Publicado 2011

Correction: Identification of Novel Genetic Markers Associated with Clinical Phenotypes of Systemic Sclerosis through a Genome-Wide Association Strategy

por Gorlova, Olga, Martin, Jose-Ezequiel, Rueda, Blanca, Koeleman, Bobby P. C., Ying, Jun, Teruel, Maria, Diaz-Gallo, Lina-Marcela, Broen, Jasper C., Vonk, Madelon C., Simeon, Carmen P., Alizadeh, Behrooz Z., Coenen, Marieke J. H., Voskuyl, Alexandre E., Schuerwegh, Annemie J., van Riel, Piet L. C. M., Vanthuyne, Marie, van 't Slot, Ruben, Italiaander, Annet, Ophoff, Roel A., Hunzelmann, Nicolas, Fonollosa, Vicente, Ortego-Centeno, Norberto, González-Gay, Miguel A., García-Hernández, Francisco J., González-Escribano, María F., Airo, Paolo, van Laar, Jacob, Worthington, Jane, Hesselstrand, Roger, Smith, Vanessa, de Keyser, Filip, Houssiau, Fredric, Chee, Meng May, Madhok, Rajan, Shiels, Paul G., Westhovens, Rene, Kreuter, Alexander, de Baere, Elfride, Witte, Torsten, Padyukov, Leonid, Nordin, Annika, Scorza, Raffaella, Lunardi, Claudio, Lie, Benedicte A., Hoffmann-Vold, Anna-Maria, Palm, Øyvind, García de la Peña, Paloma, Carreira, Patricia, Varga, John, Hinchcliff, Monique, Lee, Annette T., Gourh, Pravitt, Amos, Christopher I., Wigley, Frederick M., Hummers, Laura K., Nelson, J. Lee, Riemekasten, Gabriella, Herrick, Ariane, Beretta, Lorenzo, Fonseca, Carmen, Denton, Christopher P., Gregersen, Peter K., Agarwal, Sandeep, Assassi, Shervin, Tan, Filemon K., Arnett, Frank C., Radstake, Timothy R. D. J., Mayes, Maureen D., Martin, Javier
Publicado 2011

Correction: Identification of Novel Genetic Markers Associated with Clinical Phenotypes of Systemic Sclerosis through a Genome-Wide Association Strategy

por Gorlova, Olga, Martin, Jose-Ezequiel, Rueda, Blanca, Koeleman, Bobby P. C., Ying, Jun, Teruel, Maria, Diaz-Gallo, Lina-Marcela, Broen, Jasper C., Vonk, Madelon C., Simeon, Carmen P., Alizadeh, Behrooz Z., Coenen, Marieke J. H., Voskuyl, Alexandre E., Schuerwegh, Annemie J., van Riel, Piet L. C. M., Vanthuyne, Marie, van 't Slot, Ruben, Italiaander, Annet, Ophoff, Roel A., Hunzelmann, Nicolas, Fonollosa, Vicente, Ortego-Centeno, Norberto, González-Gay, Miguel A., García-Hernández, Francisco J., González-Escribano, María F., Airo, Paolo, van Laar, Jacob, Worthington, Jane, Hesselstrand, Roger, Smith, Vanessa, de Keyser, Filip, Houssiau, Fredric, Chee, Meng May, Madhok, Rajan, Shiels, Paul G., Westhovens, Rene, Kreuter, Alexander, de Baere, Elfride, Witte, Torsten, Padyukov, Leonid, Nordin, Annika, Scorza, Raffaella, Lunardi, Claudio, Lie, Benedicte A., Hoffmann-Vold, Anna-Maria, Palm, Øyvind, García de la Peña, Paloma, Carreira, Patricia, Varga, John, Hinchcliff, Monique, Lee, Annette T., Gourh, Pravitt, Amos, Christopher I., Wigley, Frederick M., Hummers, Laura K., Nelson, J. Lee, Riemekasten, Gabriella, Herrick, Ariane, Beretta, Lorenzo, Fonseca, Carmen, Denton, Christopher P., Gregersen, Peter K., Agarwal, Sandeep, Assassi, Shervin, Tan, Filemon K., Arnett, Frank C., Radstake, Timothy R. D. J., Mayes, Maureen D., Martin, Javier
Publicado 2011