Controversial: Early Innate Responses to Hepatitis B Virus Infection, an Explanation for Viral Persistence?

por Broering, Ruth, Luo, Xufeng, Liu, Jia, Lu, Mengji
Publicado 2020

In Vivo Mouse Models for Hepatitis B Virus Infection and Their Application

por Du, Yanqin, Broering, Ruth, Li, Xiaoran, Zhang, Xiaoyong, Liu, Jia, Yang, Dongliang, Lu, Mengji
Publicado 2021

Interferon Alpha Induces Cellular Autophagy and Modulates Hepatitis B Virus Replication

por Li, Jia, Kemper, Thekla, Broering, Ruth, Chen, Jieliang, Yuan, Zhenghong, Wang, Xueyu, Lu, Mengji
Publicado 2022

Nucleic acid-based polymers effective against hepatitis B Virus infection in patients don’t harbor immunostimulatory properties in primary isolated liver cells

por Real, Catherine Isabell, Werner, Melanie, Paul, Andreas, Gerken, Guido, Schlaak, Joerg Friedrich, Vaillant, Andrew, Broering, Ruth
Publicado 2017

Poly(I:C) Induces Distinct Liver Cell Type-Specific Responses in Hepatitis B Virus-Transgenic Mice In Vitro, but Fails to Induce These Signals In Vivo

por Schefczyk, Stefan, Luo, Xufeng, Liang, Yaojie, Trippler, Martin, Lu, Mengji, Wedemeyer, Heiner, Schmidt, Hartmut H., Broering, Ruth
Publicado 2023

Hippo Pathway Counter-Regulates Innate Immunity in Hepatitis B Virus Infection

por Luo, Xufeng, Zhang, Rui, Lu, Mengji, Liu, Shi, Baba, Hideo A., Gerken, Guido, Wedemeyer, Heiner, Broering, Ruth
Publicado 2021

Antiviral Toll-like Receptor Signaling in Non-Parenchymal Liver Cells Is Restricted to TLR3

por Werner, Melanie, Schefczyk, Stefan, Trippler, Martin, Treckmann, Juergen W., Baba, Hideo A., Gerken, Guido, Schlaak, Joerg F., Broering, Ruth
Publicado 2022

HBeAg induces liver sinusoidal endothelial cell activation to promote intrahepatic CD8 T cell immunity and HBV clearance

por Xie, Xiaohong, Luo, Jinzhuo, Broering, Ruth, Zhu, Dan, Zhou, Wenqing, Lu, Mengji, Zheng, Xin, Dittmer, Ulf, Yang, Dongliang, Liu, Jia
Publicado 2021

Retraction Note: Dickkopf-1 contributes to hepatocellular carcinoma tumorigenesis by activating the Wnt/β-catenin signaling pathway

por Zhang, Rui, Lin, Hao-Ming, Broering, Ruth, Shi, Xiang-de, Yu, Xian-huan, Xu, Lei-bo, Wu, Wen-rui, Liu, Chao
Publicado 2023

RETRACTED ARTICLE: Dickkopf-1 contributes to hepatocellular carcinoma tumorigenesis by activating the Wnt/β-catenin signaling pathway

por Zhang, Rui, Lin, Hao-Ming, Broering, Ruth, Shi, Xiang-de, Yu, Xian-huan, Xu, Lei-bo, Wu, Wen-rui, Liu, Chao
Publicado 2019

9-PAHSA Prevents Mitochondrial Dysfunction and Increases the Viability of Steatotic Hepatocytes

por Schultz Moreira, Adriana R., Rüschenbaum, Sabrina, Schefczyk, Stefan, Hendgen-Cotta, Ulrike, Rassaf, Tienush, Broering, Ruth, Hardtke-Wolenski, Matthias, Buitrago-Molina, Laura Elisa
Publicado 2020

Elevated Expression of Chemokine CXCL13 in Chronic Hepatitis B Patients Links to Immune Control during Antiviral Therapy

por Liu, Chao, Huang, Xuan, Werner, Melanie, Broering, Ruth, Ge, Jun, Li, Yongyin, Liao, Baolin, Sun, Jian, Peng, Jie, Lu, Mengji, Hou, Jinlin, Zhang, Xiaoyong
Publicado 2017

Sofosbuvir Activates EGFR-Dependent Pathways in Hepatoma Cells with Implications for Liver-Related Pathological Processes

por Bojkova, Denisa, Westhaus, Sandra, Costa, Rui, Timmer, Lejla, Funkenberg, Nora, Korencak, Marek, Streeck, Hendrik, Vondran, Florian, Broering, Ruth, Heinrichs, Stefan, Lang, Karl S, Ciesek, Sandra
Publicado 2020

Transcriptome-Wide Analysis of Human Liver Reveals Age-Related Differences in the Expression of Select Functional Gene Clusters and Evidence for a PPP1R10-Governed ‘Aging Cascade’...

por Schreiter, Thomas, Gieseler, Robert K., Vílchez-Vargas, Ramiro, Jauregui, Ruy, Sowa, Jan-Peter, Klein-Scory, Susanne, Broering, Ruth, Croner, Roland S., Treckmann, Jürgen W., Link, Alexander, Canbay, Ali
Publicado 2021

All-In-One: Advanced preparation of Human Parenchymal and Non-Parenchymal Liver Cells

por Werner, Melanie, Driftmann, Sabrina, Kleinehr, Kathrin, Kaiser, Gernot M., Mathé, Zotlan, Treckmann, Juergen-Walter, Paul, Andreas, Skibbe, Kathrin, Timm, Joerg, Canbay, Ali, Gerken, Guido, Schlaak, Joerg F., Broering, Ruth
Publicado 2015

Therapeutic Antiviral Effect of the Nucleic Acid Polymer REP 2055 against Persistent Duck Hepatitis B Virus Infection

por Noordeen, Faseeha, Scougall, Catherine A., Grosse, Arend, Qiao, Qiao, Ajilian, Behzad B., Reaiche-Miller, Georget, Finnie, John, Werner, Melanie, Broering, Ruth, Schlaak, Joerg F., Vaillant, Andrew, Jilbert, Allison R.
Publicado 2015

Peripheral blood iNKT cell activation correlates with liver damage during acute hepatitis C

por Senff, Tina, Menne, Christopher, Cosmovici, Christine, Lewis-Ximenez, Lia Laura, Aneja, Jasneet, Broering, Ruth, Kim, Arthur Y., Westendorf, Astrid M., Dittmer, Ulf, Scherbaum, Norbert, Lauer, Georg M., Timm, Jörg
Publicado 2022

Human hepatocyte-enriched miRNA-192-3p promotes HBV replication through inhibiting Akt/mTOR signalling by targeting ZNF143 in hepatic cell lines

por Li, Fahong, Deng, Yingying, Zhang, Shenyan, Zhu, Beidi, Wang, Jun, Wang, Jinyu, Wang, Xueyu, Zhao, Zhenyu, Deng, Wanyu, Mao, Richeng, Shen, Zhongliang, Chen, Jieliang, Broering, Ruth, Lin, Yong, Lu, Mengji, Zhang, Jiming
Publicado 2022

Hepatitis B virus rigs the cellular metabolome to avoid innate immune recognition

por Zhou, Li, He, Rui, Fang, Peining, Li, Mengqi, Yu, Haisheng, Wang, Qiming, Yu, Yi, Wang, Fubing, Zhang, Yi, Chen, Aidong, Peng, Nanfang, Lin, Yong, Zhang, Rui, Trilling, Mirko, Broering, Ruth, Lu, Mengji, Zhu, Ying, Liu, Shi
Publicado 2021

EGF receptor modulates HEV entry in human hepatocytes

por Schrader, Jil A., Burkard, Thomas L., Brüggemann, Yannick, Gömer, André, Meister, Toni L., Fu, Rebecca M., Mehnert, Ann-Kathrin, Dao Thi, Viet L., Behrendt, Patrick, Durantel, David, Broering, Ruth, Vondran, Florian W. R., Todt, Daniel, Kinast, Volker, Steinmann, Eike
Publicado 2023