NKG2D Fine-Tunes the Local Inflammatory Response in Colorectal Cancer

por Curio, Sophie, Lin, Wanzun, Bromley, Christian, McGovern, Jenny, Triulzi, Chiara, Jonsson, Gustav, Ghislat, Ghita, Zelenay, Santiago, Guerra, Nadia
Publicado 2023

RNA sensing via the RIG‐I‐like receptor LGP2 is essential for the induction of a type I IFN response in ADAR1 deficiency

por Stok, Jorn E, Oosenbrug, Timo, ter Haar, Laurens R, Gravekamp, Dennis, Bromley, Christian P, Zelenay, Santiago, Reis e Sousa, Caetano, van der Veen, Annemarthe G
Publicado 2022

Chemotherapy-induced COX-2 upregulation by cancer cells defines their inflammatory properties and limits the efficacy of chemoimmunotherapy combinations

por Bell, Charlotte R., Pelly, Victoria S., Moeini, Agrin, Chiang, Shih-Chieh, Flanagan, Eimear, Bromley, Christian P., Clark, Christopher, Earnshaw, Charles H., Koufaki, Maria A., Bonavita, Eduardo, Zelenay, Santiago
Publicado 2022

DNGR-1 limits Flt3L-mediated antitumor immunity by restraining tumor-infiltrating type I conventional dendritic cells

por Cueto, Francisco J, del Fresno, Carlos, Brandi, Paola, Combes, Alexis J., Hernández-García, Elena, Sánchez-Paulete, Alfonso R, Enamorado, Michel, Bromley, Christian P, Gomez, Manuel J, Conde-Garrosa, Ruth, Mañes, Santos, Zelenay, Santiago, Melero, Ignacio, Iborra, Salvador, Krummel, Matthew F., Sancho, David
Publicado 2021

Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade

por Bonavita, Eduardo, Bromley, Christian P., Jonsson, Gustav, Pelly, Victoria S., Sahoo, Sudhakar, Walwyn-Brown, Katherine, Mensurado, Sofia, Moeini, Agrin, Flanagan, Eimear, Bell, Charlotte R., Chiang, Shih-Chieh, Chikkanna-Gowda, C.P., Rogers, Neil, Silva-Santos, Bruno, Jaillon, Sebastien, Mantovani, Alberto, Reis e Sousa, Caetano, Guerra, Nadia, Davis, Daniel M., Zelenay, Santiago
Publicado 2020