Influenza A Virus Superinfection Potential Is Regulated by Viral Genomic Heterogeneity

por Sun, Jiayi, Brooke, Christopher B.
Publicado 2018

What’s New with Flu? An Overview

por Lakdawala, Seema S., Brooke, Christopher B.
Publicado 2019

Low Viral Diversity Limits the Effectiveness of Sequence-Based Transmission Inference for SARS-CoV-2

por Farjo, Mireille, Brooke, Christopher B.
Publicado 2023

Influenza virus DI particles: Defective interfering or delightfully interesting?

por Alnaji, Fadi G., Brooke, Christopher B.
Publicado 2020

Causes and Consequences of Spatial Within-Host Viral Spread

por Gallagher, Molly E., Brooke, Christopher B., Ke, Ruian, Koelle, Katia
Publicado 2018

Within-host infectious disease models accommodating cellular coinfection, with an application to influenza(†)

por Koelle, Katia, Farrell, Alex P, Brooke, Christopher B, Ke, Ruian
Publicado 2019

Semi-infectious particles contribute substantially to influenza virus within-host dynamics when infection is dominated by spatial structure

por Farrell, Alex, Phan, Tin, Brooke, Christopher B, Koelle, Katia, Ke, Ruian
Publicado 2023

Cellular co-infection can modulate the efficiency of influenza A virus production and shape the interferon response

por Martin, Brigitte E., Harris, Jeremy D., Sun, Jiayi, Koelle, Katia, Brooke, Christopher B.
Publicado 2020

Single cell heterogeneity in influenza A virus gene expression shapes the innate antiviral response to infection

por Sun, Jiayi, Vera, J. Cristobal, Drnevich, Jenny, Lin, Yen Ting, Ke, Ruian, Brooke, Christopher B.
Publicado 2020

Diversity and Complexity of Internally Deleted Viral Genomes in Influenza A Virus Subpopulations with Enhanced Interferon-Inducing Phenotypes

por Ghorbani, Amir, Ngunjiri, John M., Rendon, Gloria, Brooke, Christopher B., Kenney, Scott P., Lee, Chang-Won
Publicado 2023

Influenza A Virus Defective Viral Genomes Are Inefficiently Packaged into Virions Relative to Wild-Type Genomic RNAs

por Alnaji, Fadi G., Reiser, William K., Rivera-Cardona, Joel, te Velthuis, Aartjan J. W., Brooke, Christopher B.
Publicado 2021

Semi-continuous Propagation of Influenza A Virus and Its Defective Interfering Particles: Analyzing the Dynamic Competition To Select Candidates for Antiviral Therapy

por Pelz, Lars, Rüdiger, Daniel, Dogra, Tanya, Alnaji, Fadi G., Genzel, Yvonne, Brooke, Christopher B., Kupke, Sascha Y., Reichl, Udo
Publicado 2021

Neuraminidase inhibition contributes to influenza A virus neutralization by anti-hemagglutinin stem antibodies

por Kosik, Ivan, Angeletti, Davide, Gibbs, James S., Angel, Matthew, Takeda, Kazuyo, Kosikova, Martina, Nair, Vinod, Hickman, Heather D., Xie, Hang, Brooke, Christopher B., Yewdell, Jonathan W.
Publicado 2019

Influenza A virus hemagglutinin glycosylation compensates for antibody escape fitness costs

por Kosik, Ivan, Ince, William L., Gentles, Lauren E., Oler, Andrew J., Kosikova, Martina, Angel, Matthew, Magadán, Javier G., Xie, Hang, Brooke, Christopher B., Yewdell, Jonathan W.
Publicado 2018

Correction: Influenza A virus hemagglutinin glycosylation compensates for antibody escape fitness costs

por Kosik, Ivan, Ince, William L., Gentles, Lauren E., Oler, Andrew J., Kosikova, Martina, Angel, Matthew, Magadán, Javier G., Xie, Hang, Brooke, Christopher B., Yewdell, Jonathan W.
Publicado 2018

Prevalence and mechanisms of evolutionary contingency in human influenza H3N2 neuraminidase

por Lei, Ruipeng, Tan, Timothy J. C., Hernandez Garcia, Andrea, Wang, Yiquan, Diefenbacher, Meghan, Teo, Chuyun, Gopan, Gopika, Tavakoli Dargani, Zahra, Teo, Qi Wen, Graham, Claire S., Brooke, Christopher B., Nair, Satish K., Wu, Nicholas C.
Publicado 2022

Sequence signatures of two IGHV3-53/3-66 public clonotypes to SARS-CoV-2 receptor binding domain

por Tan, Timothy J.C., Yuan, Meng, Kuzelka, Kaylee, Padron, Gilberto C., Beal, Jacob R., Chen, Xin, Wang, Yiquan, Rivera-Cardona, Joel, Zhu, Xueyong, Stadtmueller, Beth M., Brooke, Christopher B., Wilson, Ian A., Wu, Nicholas C.
Publicado 2021

Sequence signatures of two public antibody clonotypes that bind SARS-CoV-2 receptor binding domain

por Tan, Timothy J. C., Yuan, Meng, Kuzelka, Kaylee, Padron, Gilberto C., Beal, Jacob R., Chen, Xin, Wang, Yiquan, Rivera-Cardona, Joel, Zhu, Xueyong, Stadtmueller, Beth M., Brooke, Christopher B., Wilson, Ian A., Wu, Nicholas C.
Publicado 2021

Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2

por Drayman, Nir, DeMarco, Jennifer K., Jones, Krysten A., Azizi, Saara-Anne, Froggatt, Heather M., Tan, Kemin, Maltseva, Natalia Ivanovna, Chen, Siquan, Nicolaescu, Vlad, Dvorkin, Steve, Furlong, Kevin, Kathayat, Rahul S., Firpo, Mason R., Mastrodomenico, Vincent, Bruce, Emily A., Schmidt, Madaline M., Jedrzejczak, Robert, Muñoz-Alía, Miguel Á., Schuster, Brooke, Nair, Vishnu, Han, Kyu-yeon, O’Brien, Amornrat, Tomatsidou, Anastasia, Meyer, Bjoern, Vignuzzi, Marco, Missiakas, Dominique, Botten, Jason W., Brooke, Christopher B., Lee, Hyun, Baker, Susan C., Mounce, Bryan C., Heaton, Nicholas S., Severson, William E., Palmer, Kenneth E., Dickinson, Bryan C., Joachimiak, Andrzej, Randall, Glenn, Tay, Savaş
Publicado 2021

Daily longitudinal sampling of SARS-CoV-2 infection reveals substantial heterogeneity in infectiousness

por Ke, Ruian, Martinez, Pamela P., Smith, Rebecca L., Gibson, Laura L., Mirza, Agha, Conte, Madison, Gallagher, Nicholas, Luo, Chun Huai, Jarrett, Junko, Zhou, Ruifeng, Conte, Abigail, Liu, Tongyu, Farjo, Mireille, Walden, Kimberly K.O., Rendon, Gloria, Fields, Christopher J., Wang, Leyi, Fredrickson, Richard, Edmonson, Darci C., Baughman, Melinda E., Chiu, Karen K., Choi, Hannah, Scardina, Kevin R., Bradley, Shannon, Gloss, Stacy L., Reinhart, Crystal, Yedetore, Jagadeesh, Quicksall, Jessica, Owens, Alyssa N., Broach, John, Barton, Bruce, Lazar, Peter, Heetderks, William J., Robinson, Matthew L., Mostafa, Heba H., Manabe, Yukari C., Pekosz, Andrew, McManus, David D., Brooke, Christopher B.
Publicado 2022