The utilisation of operant delayed matching and non-matching to position for probing cognitive flexibility and working memory in mouse models of Huntington's disease

por Yhnell, Emma, Dunnett, Stephen B., Brooks, Simon P.
Publicado 2016

A Longitudinal Motor Characterisation of the Hdh(Q111) Mouse Model of Huntington’s Disease

por Yhnell, Emma, Dunnett, Stephen B., Brooks, Simon P.
Publicado 2016

A Longitudinal Operant Assessment of Cognitive and Behavioural Changes in the Hdh(Q111) Mouse Model of Huntington’s Disease

por Yhnell, Emma, Dunnett, Stephen B., Brooks, Simon P.
Publicado 2016

Huntingtin Subcellular Localisation Is Regulated by Kinase Signalling Activity in the StHdh(Q111) Model of HD

por Bowles, Kathryn R., Brooks, Simon P., Dunnett, Stephen B., Jones, Lesley
Publicado 2015

Comparison of mHTT Antibodies in Huntington’s Disease Mouse Models Reveal Specific Binding Profiles and Steady-State Ubiquitin Levels with Disease Development

por Bayram-Weston, Zubeyde, Jones, Lesley, Dunnett, Stephen B., Brooks, Simon P.
Publicado 2016

Cognitive training modifies disease symptoms in a mouse model of Huntington's disease

por Yhnell, Emma, Lelos, Mariah J., Dunnett, Stephen B., Brooks, Simon P.
Publicado 2016

Optimising Golgi–Cox staining for use with perfusion-fixed brain tissue validated in the zQ175 mouse model of Huntington's disease

por Bayram-Weston, Zubeyde, Olsen, Elliott, Harrison, David J., Dunnett, Stephen B., Brooks, Simon P.
Publicado 2016

Correction: Huntingtin Subcellular Localisation Is Regulated by Kinase Signalling Activity in the StHdh(Q111) Model of HD

por Bowles, Kathryn R., Brooks, Simon P., Hughes, Alis C., Dunnett, Stephen B., Jones, Lesley
Publicado 2016

Identification of three novel NHS mutations in families with Nance-Horan syndrome

por Huang, Kristen M., Wu, Junhua, Brooks, Simon P., Hardcastle, Alison J., Lewis, Richard Alan, Stambolian, Dwight
Publicado 2007

The Effect of Tissue Preparation and Donor Age on Striatal Graft Morphology in the Mouse

por Harrison, David J., Roberton, Victoria H., Vinh, Ngoc-Nga, Brooks, Simon P., Dunnett, Stephen B., Rosser, Anne E.
Publicado 2018

The Nance–Horan syndrome protein encodes a functional WAVE homology domain (WHD) and is important for co-ordinating actin remodelling and maintaining cell morphology

por Brooks, Simon P., Coccia, Margherita, Tang, Hao R., Kanuga, Naheed, Machesky, Laura M., Bailly, Maryse, Cheetham, Michael E., Hardcastle, Alison J.
Publicado 2010

CTIP2-Regulated Reduction in PKA-Dependent DARPP32 Phosphorylation in Human Medium Spiny Neurons: Implications for Huntington Disease

por Fjodorova, Marija, Louessard, Morgane, Li, Zongze, De La Fuente, Daniel C., Dyke, Emma, Brooks, Simon P., Perrier, Anselme L., Li, Meng
Publicado 2019

Similar striatal gene expression profiles in the striatum of the YAC128 and HdhQ150 mouse models of Huntington’s disease are not reflected in mutant Huntingtin inclusion prevalence...

por Bayram-Weston, Zubeyde, Stone, Timothy C., Giles, Peter, Elliston, Linda, Janghra, Nari, Higgs, Gemma V., Holmans, Peter A., Dunnett, Stephen B., Brooks, Simon P., Jones, Lesley
Publicado 2015

Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand

por McWilliams, Thomas G., Prescott, Alan R., Montava-Garriga, Lambert, Ball, Graeme, Singh, François, Barini, Erica, Muqit, Miratul M.K., Brooks, Simon P., Ganley, Ian G.
Publicado 2018

Loss of CRMP2 O-GlcNAcylation leads to reduced novel object recognition performance in mice

por Muha, Villo, Williamson, Ritchie, Hills, Rachel, McNeilly, Alison D., McWilliams, Thomas G., Alonso, Jana, Schimpl, Marianne, Leney, Aneika C., Heck, Albert J. R., Sutherland, Calum, Read, Kevin D., McCrimmon, Rory J., Brooks, Simon P., van Aalten, Daan M. F.
Publicado 2019

X-linked cataract and Nance-Horan syndrome are allelic disorders

por Coccia, Margherita, Brooks, Simon P., Webb, Tom R., Christodoulou, Katja, Wozniak, Izabella O., Murday, Victoria, Balicki, Martha, Yee, Harris A., Wangensteen, Teresia, Riise, Ruth, Saggar, Anand K., Park, Soo-Mi, Kanuga, Naheed, Francis, Peter J., Maher, Eamonn R., Moore, Anthony T., Russell-Eggitt, Isabelle M., Hardcastle, Alison J.
Publicado 2009

Motivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6.Htt(Q111/+) model of Huntington’s disease

por Bragg, Robert M., Coffey, Sydney R., Weston, Rory M., Ament, Seth A., Cantle, Jeffrey P., Minnig, Shawn, Funk, Cory C., Shuttleworth, Dominic D., Woods, Emily L., Sullivan, Bonnie R., Jones, Lindsey, Glickenhaus, Anne, Anderson, John S., Anderson, Michael D., Dunnett, Stephen B., Wheeler, Vanessa C., MacDonald, Marcy E., Brooks, Simon P., Price, Nathan D., Carroll, Jeffrey B.
Publicado 2017

Corrigendum: Motivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6.Htt(Q111/+) model of Huntington’s disease

por Bragg, Robert M., Coffey, Sydney R., Weston, Rory M., Ament, Seth A., Cantle, Jeffrey P., Minnig, Shawn, Funk, Cory C., Shuttleworth, Dominic D., Woods, Emily L., Sullivan, Bonnie R., Jones, Lindsey, Glickenhaus, Anne, Anderson, John S., Anderson, Michael D., Dunnett, Stephen B., Wheeler, Vanessa C., MacDonald, Marcy E., Brooks, Simon P., Price, Nathan D., Carroll, Jeffrey B.
Publicado 2017

Phosphorylation of Parkin at serine 65 is essential for its activation in vivo

por McWilliams, Thomas G., Barini, Erica, Pohjolan-Pirhonen, Risto, Brooks, Simon P., Singh, François, Burel, Sophie, Balk, Kristin, Kumar, Atul, Montava-Garriga, Lambert, Prescott, Alan R., Hassoun, Sidi Mohamed, Mouton-Liger, François, Ball, Graeme, Hills, Rachel, Knebel, Axel, Ulusoy, Ayse, Di Monte, Donato A., Tamjar, Jevgenia, Antico, Odetta, Fears, Kyle, Smith, Laura, Brambilla, Riccardo, Palin, Eino, Valori, Miko, Eerola-Rautio, Johanna, Tienari, Pentti, Corti, Olga, Dunnett, Stephen B., Ganley, Ian G., Suomalainen, Anu, Muqit, Miratul M. K.
Publicado 2018