Hypoxia-inducible factor-1alpha is a critical mediator of hypoxia induced apoptosis in cardiac H9c2 and kidney epithelial HK-2 cells

por Malhotra, Ricky, Tyson, David W, Rosevear, Henry M, Brosius, Frank C
Publicado 2008

Inability of Serotonin to Activate the c-Jun N-terminal Kinase and p38 Kinase Pathways in Rat Aortic Vascular Smooth Muscle Cells

por Banes, Amy KL, Loberg, Robert D, Brosius, Frank C, Watts, Stephanie W
Publicado 2001

Reduction in podocyte density as a pathologic feature in early diabetic nephropathy in rodents: Prevention by lipoic acid treatment

por Siu, Brian, Saha, Jharna, Smoyer, William E, Sullivan, Kelli A, Brosius, Frank C
Publicado 2006

Maintenance of GLUT4 expression in smooth muscle prevents hypertension-induced changes in vascular reactivity

por Atkins, Kevin B, Seki, Yoshinori, Saha, Jharna, Eichinger, Felix, Charron, Maureen J, Brosius, Frank C
Publicado 2015

Targeted Lipidomic and Transcriptomic Analysis Identifies Dysregulated Renal Ceramide Metabolism in a Mouse Model of Diabetic Kidney Disease

por Sas, Kelli M, Nair, Viji, Byun, Jaeman, Kayampilly, Pradeep, Zhang, Hongyu, Saha, Jharna, Brosius, Frank C, Kretzler, Matthias, Pennathur, Subramaniam
Publicado 2015

Comparative RNA‐Seq transcriptome analyses reveal distinct metabolic pathways in diabetic nerve and kidney disease

por Hinder, Lucy M., Park, Meeyoung, Rumora, Amy E., Hur, Junguk, Eichinger, Felix, Pennathur, Subramaniam, Kretzler, Matthias, Brosius, Frank C., Feldman, Eva L.
Publicado 2017

The Metabolic Syndrome and Microvascular Complications in a Murine Model of Type 2 Diabetes

por Hur, Junguk, Dauch, Jacqueline R., Hinder, Lucy M., Hayes, John M., Backus, Carey, Pennathur, Subramaniam, Kretzler, Matthias, Brosius, Frank C., Feldman, Eva L.
Publicado 2015

Podocyte specific knock out of selenoproteins does not enhance nephropathy in streptozotocin diabetic C57BL/6 mice

por Blauwkamp, Marsha N, Yu, Jingcheng, Schin, MaryLee A, Burke, Kathleen A, Berry, Marla J, Carlson, Bradley A, Brosius, Frank C, Koenig, Ronald J
Publicado 2008

Serum amyloid A and Janus kinase 2 in a mouse model of diabetic kidney disease

por Dieter, Brad P., Meek, Rick L., Anderberg, Robert J., Cooney, Sheryl K., Bergin, Jen L., Zhang, Hongyu, Nair, Viji, Kretzler, Matthias, Brosius, Frank C., Tuttle, Katherine R.
Publicado 2019

Identification of Cross-Species Shared Transcriptional Networks of Diabetic Nephropathy in Human and Mouse Glomeruli

por Hodgin, Jeffrey B., Nair, Viji, Zhang, Hongyu, Randolph, Ann, Harris, Raymond C., Nelson, Robert G., Weil, E. Jennifer, Cavalcoli, James D., Patel, Jignesh M., Brosius, Frank C., Kretzler, Matthias
Publicado 2013

Consent for Genetic Biobanking in a Diverse Multisite CKD Cohort

por Troost, Jonathan P., Hawkins, Jennifer, Jenkins, Daniel R., Gipson, Debbie S., Kretzler, Matthias, El Shamy, Osama, Bellovich, Keith, Perumal, Kalyani, Bhat, Zeenat, Massengill, Susan, Steigerwalt, Susan, Pennathur, Subramaniam, Brosius, Frank C., Gadegbeku, Crystal A.
Publicado 2018

Differential effects of minocycline on microvascular complications in murine models of type 1 and type 2 diabetes

por Eid, Stephanie A., O’Brien, Phillipe D., Hinder, Lucy M., Hayes, John M., Mendelson, Faye E., Zhang, Hongyu, Narayanan, Samanthi, Abcouwer, Steven F., Brosius, Frank C., Pennathur, Subramaniam, Savelieff, Masha G., Feldman, Eva L.
Publicado 2020

The deacylase sirtuin 5 reduces malonylation in nonmitochondrial metabolic pathways in diabetic kidney disease

por Baek, Judy, Sas, Kelli, He, Chenchen, Nair, Viji, Giblin, William, Inoki, Ayaka, Zhang, Hongyu, Yingbao, Yang, Hodgin, Jeffrey, Nelson, Robert G., Brosius, Frank C., Kretzler, Matthias, Stemmer, Paul M., Lombard, David B., Pennathur, Subramaniam
Publicado 2023

Enhanced Expression of Janus Kinase–Signal Transducer and Activator of Transcription Pathway Members in Human Diabetic Nephropathy

por Berthier, Celine C., Zhang, Hongyu, Schin, MaryLee, Henger, Anna, Nelson, Robert G., Yee, Berne, Boucherot, Anissa, Neusser, Matthias A., Cohen, Clemens D., Carter-Su, Christin, Argetsinger, Lawrence S., Rastaldi, Maria P., Brosius, Frank C., Kretzler, Matthias
Publicado 2009

Mitochondrial uncoupling has no effect on microvascular complications in type 2 diabetes

por Hinder, Lucy M., Sas, Kelli M., O’Brien, Phillipe D., Backus, Carey, Kayampilly, Pradeep, Hayes, John M., Lin, Cheng-mao, Zhang, Hongyu, Shanmugam, Sumathi, Rumora, Amy E., Abcouwer, Steven F., Brosius, Frank C., Pennathur, Subramaniam, Feldman, Eva L.
Publicado 2019

Differential Effects of Empagliflozin on Microvascular Complications in Murine Models of Type 1 and Type 2 Diabetes

por Eid, Stephanie A., O’Brien, Phillipe D., Hinder, Lucy M., Hayes, John M., Mendelson, Faye E., Zhang, Hongyu, Zeng, Lixia, Kretzler, Katharina, Narayanan, Samanthi, Abcouwer, Steven F., Brosius, Frank C., Pennathur, Subramaniam, Savelieff, Masha G., Feldman, Eva L.
Publicado 2020

Transcriptomic analysis of diabetic kidney disease and neuropathy in mouse models of type 1 and type 2 diabetes

por Elzinga, Sarah E., Eid, Stephanie A., McGregor, Brett A., Jang, Dae-Gyu, Hinder, Lucy M., Dauch, Jacqueline R., Hayes, John M., Zhang, Hongyu, Guo, Kai, Pennathur, Subramaniam, Kretzler, Matthias, Brosius, Frank C., Koubek, Emily J., Feldman, Eva L., Hur, Junguk
Publicado 2023

Data from network meta-analyses can inform clinical practice guidelines and decision-making in diabetes management: perspectives of the taskforce of the guideline workshop

por Ceriello, Antonio, Rodbard, Helena W., Battelino, Tadej, Brosius, Frank, Cosentino, Francesco, Green, Jennifer, Ji, Linong, Kellerer, Monika, Koob, Susan, Kosiborod, Mikhail, Lalic, Nebojsa, Marx, Nikolaus, Nedungadi, T. Prashant, Parkin, Christopher G., Rydén, Lars, Sheu, Wayne Huey-Herng, Standl, Eberhard, Vandvik, Per Olav, Schnell, Oliver
Publicado 2023

Soluble ST2 and Galectin-3 and Progression of CKD

por Alam, Mariam L., Katz, Ronit, Bellovich, Keith A., Bhat, Zeenat Y., Brosius, Frank C., de Boer, Ian H., Gadegbeku, Crystal A., Gipson, Debbie S., Hawkins, Jennifer J., Himmelfarb, Jonathan, Kestenbaum, Bryan R., Kretzler, Matthias, Robinson-Cohen, Cassianne, Steigerwalt, Susan P., Tuegel, Courtney, Bansal, Nisha
Publicado 2018

JAK1/JAK2 inhibition by baricitinib in diabetic kidney disease: results from a Phase 2 randomized controlled clinical trial

por Tuttle, Katherine R, Brosius, Frank C, Adler, Sharon G, Kretzler, Matthias, Mehta, Ravindra L, Tumlin, James A, Tanaka, Yoshiya, Haneda, Masakazu, Liu, Jiajun, Silk, Maria E, Cardillo, Tracy E, Duffin, Kevin L, Haas, Joseph V, Macias, William L, Nunes, Fabio P, Janes, Jonathan M
Publicado 2018