A New Gorilla Adenoviral Vector with Natural Lung Tropism Avoids Liver Toxicity and Is Amenable to Capsid Engineering and Vector Retargeting

por Lu, Zhi Hong, Dmitriev, Igor P., Brough, Douglas E., Kashentseva, Elena A., Li, Jie, Curiel, David T.
Publicado 2020

Selective atonal gene delivery improves balance function in a mouse model of vestibular disease

por Schlecker, Christina, Praetorius, Mark, Brough, Douglas E., Presler, Robert G., Hsu, Chi, Plinkert, Peter K., Staecker, Hinrich
Publicado 2011

Alternate serotype adenovector provides long-term therapeutic gene expression in the eye

por Hamilton, Melissa M., Byrnes, Gordon A., Gall, Jason G., Brough, Douglas E., King, C. Richter, Wei, Lisa L.
Publicado 2008

Preclinical study of a novel therapeutic vaccine for recurrent respiratory papillomatosis

por Lee, Maxwell Y., Metenou, Simon, Brough, Douglas E., Sabzevari, Helen, Bai, Ke, Jochems, Caroline, Schlom, Jeffrey, Allen, Clint T.
Publicado 2021

Impaired Regulation by IL-35 in Systemic Sclerosis

por Osuna-Gómez, Rubén, Castellví, Ivan, Mulet, Maria, Ortiz, Mª Àngels, Brough, Douglas E., Sabzevari, Helen, Semnani, Roshanak T., Vidal, Silvia
Publicado 2023

Ocular Localization and Transduction by Adenoviral Vectors Are Serotype-Dependent and Can Be Modified by Inclusion of RGD Fiber Modifications

por Ueyama, Kazuhiro, Mori, Keisuke, Shoji, Takuhei, Omata, Hidekazu, Gehlbach, Peter L., Brough, Douglas E., Wei, Lisa L., Yoneya, Shin
Publicado 2014

Improving Control of Gene Therapy-Based Neurotrophin Delivery for Inner Ear Applications

por St. Peter, Madeleine, Brough, Douglas E., Lawrence, Anna, Nelson-Brantley, Jennifer, Huang, Peixin, Harre, Jennifer, Warnecke, Athanasia, Staecker, Hinrich
Publicado 2022

A Gorilla Adenovirus-Based Vaccine against Zika Virus Induces Durable Immunity and Confers Protection in Pregnancy

por Hassan, Ahmed O., Dmitriev, Igor P., Kashentseva, Elena A., Zhao, Haiyan, Brough, Douglas E., Fremont, Daved H., Curiel, David T., Diamond, Michael S.
Publicado 2019

Characterization of recombinant gorilla adenovirus HPV therapeutic vaccine PRGN-2009

por Pellom, Samuel T., Smalley Rumfield, Claire, Morillon, Y. Maurice, Roller, Nicholas, Poppe, Lisa K., Brough, Douglas E., Sabzevari, Helen, Schlom, Jeffrey, Jochems, Caroline
Publicado 2021

Characterization of human adenovirus 35 and derivation of complex vectors

por McVey, Duncan, Zuber, Mohammed, EttyReddy, Damodar, Reiter, Christopher D, Brough, Douglas E, Nabel, Gary J, King, C Richter, Gall, Jason G D
Publicado 2010

Efficacy of an adenovirus-vectored foot-and-mouth disease virus serotype A subunit vaccine in cattle using a direct contact transmission model

por Neilan, John G., Schutta, Christopher, Barrera, José, Pisano, Melia, Zsak, Laszlo, Hartwig, Ethan, Rasmussen, Max V., Kamicker, Barbara J., Ettyreddy, Damodar, Brough, Douglas E., Butman, Bryan T., Brake, David A.
Publicado 2018

Profiling the Targets of Protective CD8(+) T Cell Responses to Infection

por Bruder, Joseph T., Chen, Ping, Ekberg, Greg, Smith, Emily C., Lazarski, Christopher A., Myers, Bennett A., Bolton, Jessica, Sedegah, Martha, Villasante, Eileen, Richie, Thomas L., King, C. Richter, Aguiar, Joao C., Doolan, Denise L., Brough, Douglas E.
Publicado 2017

New gorilla adenovirus vaccine vectors induce potent immune responses and protection in a mouse malaria model

por Limbach, Keith, Stefaniak, Maureen, Chen, Ping, Patterson, Noelle B., Liao, Grant, Weng, Shaojie, Krepkiy, Svetlana, Ekberg, Greg, Torano, Holly, Ettyreddy, Damodar, Gowda, Kalpana, Sonawane, Sharvari, Belmonte, Arnel, Abot, Esteban, Sedegah, Martha, Hollingdale, Michael R., Moormann, Ann, Vulule, John, Villasante, Eileen, Richie, Thomas L., Brough, Douglas E., Bruder, Joseph T.
Publicado 2017