Biochemical mechanism and biological effects of the inhibition of silent information regulator 1 (SIRT1) by EX-527 (SEN0014196 or selisistat)

por Broussy, Sylvain, Laaroussi, Hanna, Vidal, Michel
Publicado 2020

Editorial: Computer-aided drug design: Drug discovery, computational modelling, and artificial intelligence

por Ye, Fei, Lin, Min, Jin, Jia, Broussy, Sylvain
Publicado 2022

Structural and ITC Characterization of Peptide‐Protein Binding: Thermodynamic Consequences of Cyclization Constraints, a Case Study on Vascular Endothelial Growth Factor Ligands

por Gaucher, Jean‐François, Reille‐Seroussi, Marie, Broussy, Sylvain
Publicado 2022

A Structural Overview of Vascular Endothelial Growth Factors Pharmacological Ligands: From Macromolecules to Designed Peptidomimetics

por Ye, Xiaoqing, Gaucher, Jean-François, Vidal, Michel, Broussy, Sylvain
Publicado 2021

Use of a Robust Dehydrogenase from an Archael Hyperthermophile in Asymmetric Catalysis−Dynamic Reductive Kinetic Resolution Entry into (S)-Profens

por Friest, Jacob A., Maezato, Yukari, Broussy, Sylvain, Blum, Paul, Berkowitz, David B.
Publicado 2010

Correlation between afferent rearrangements and behavioral deficits after local excitotoxic insult in the mammalian vestibule: a rat model of vertigo symptoms

por Gaboyard-Niay, Sophie, Travo, Cécile, Saleur, Aurélie, Broussy, Audrey, Brugeaud, Aurore, Chabbert, Christian
Publicado 2016

Design and Synthesis of C-Terminal Modified Cyclic Peptides as VEGFR1 Antagonists

por Wang, Lei, Gagey-Eilstein, Nathalie, Broussy, Sylvain, Reille-Seroussi, Marie, Huguenot, Florent, Vidal, Michel, Liu, Wang-Qing
Publicado 2014

A VEGFB-Based Peptidomimetic Inhibits VEGFR2-Mediated PI3K/Akt/mTOR and PLCγ/ERK Signaling and Elicits Apoptotic, Antiangiogenic, and Antitumor Activities

por Namjoo, Mohadeseh, Ghafouri, Hossein, Assareh, Elham, Aref, Amir Reza, Mostafavi, Ebrahim, Hamrahi Mohsen, Ali, Balalaie, Saeed, Broussy, Sylvain, Asghari, S. Mohsen
Publicado 2023

Mini-ISES identifies promising carbafructopyranose-based salens for asymmetric catalysis: Tuning ligand shape via the anomeric effect

por Karukurichi, Kannan R., Fei, Xiang, Swyka, Robert A., Broussy, Sylvain, Shen, Weijun, Dey, Sangeeta, Roy, Sandip K., Berkowitz, David B.
Publicado 2015

Molecular docking, synthesis and biological evaluation of Vascular Endothelial Growth Factor (VEGF) B based peptide as antiangiogenic agent targeting the second domain of the Vascu...

por Sadremomtaz, Afsaneh, Ali, Ameena M., Jouyandeh, Foroozan, Balalaie, Saeed, Navari, Razieh, Broussy, Sylvain, Mansouri, Kamran, Groves, Matthew R., Asghari, S. Mohsen
Publicado 2020

Sequelae and Quality of Life in Patients Living at Home 1 Year After a Stroke Managed in Stroke Units

por Broussy, Sophie, Saillour-Glenisson, Florence, García-Lorenzo, B., Rouanet, Francois, Lesaine, Emilie, Maugeais, Melanie, Aly, Florence, Glize, Bertrand, Salamon, Roger, Sibon, Igor
Publicado 2019

Post-stroke pathway analysis and link with one year sequelae in a French cohort of stroke patients: the PAPASePA protocol study

por Broussy, S., Rouanet, F., Lesaine, E., Domecq, S., Kret, M., Maugeais, M., Aly, F., Dehail, P., Bénard, A., Wittwer, J., Salamon, R., Sibon, I., Saillour-Glenisson, F.
Publicado 2019

A Cyclic Peptide Epitope of an Under-Explored VEGF-B Loop 1 Demonstrated In Vivo Anti-Angiogenic and Anti-Tumor Activities

por Wang, Lei, Xu, Meng, Hu, Haofeng, Zhang, Lun, Ye, Fei, Jin, Jia, Fang, Hongming, Chen, Jian, Chen, Guiqian, Broussy, Sylvain, Vidal, Michel, Lv, Zhengbing, Liu, Wang-Qing
Publicado 2021

Biophysical Studies of the Induced Dimerization of Human VEGF Receptor 1 Binding Domain by Divalent Metals Competing with VEGF-A

por Gaucher, Jean-François, Reille-Seroussi, Marie, Gagey-Eilstein, Nathalie, Broussy, Sylvain, Coric, Pascale, Seijo, Bili, Lascombe, Marie-Bernard, Gautier, Benoit, Liu, Wang-Quing, Huguenot, Florent, Inguimbert, Nicolas, Bouaziz, Serge, Vidal, Michel, Broutin, Isabelle
Publicado 2016