CREPT Promotes Melanoma Progression Through Accelerated Proliferation and Enhanced Migration by RhoA-Mediated Actin Filaments and Focal Adhesion Formation

por Liu, Hui, Seynhaeve, Ann L. B., Brouwer, Rutger W. W., van IJcken, Wilfred F. J., Yang, Liu, Wang, Yinyin, Chang, Zhijie, ten Hagen, Timo L. M.
Publicado 2019

Identification of candidate enhancers controlling the transcriptome during the formation of interphalangeal joints

por Nowosad, Karol, Brouwer, Rutger W. W., Odrzywolski, Adrian, Korporaal, Anne L., Gielniewski, Bartłomiej, Wojtaś, Bartosz, van IJcken, Wilfred F. J., Grosveld, Frank, Huylebroeck, Danny, Tylzanowski, Przemko
Publicado 2022

Effect of bovine milk fat-based infant formulae on microbiota, metabolites and stool parameters in healthy term infants in a randomized, crossover, placebo-controlled trial

por Looijesteijn, Ellen, Brouwer, Rutger W. W., Schoemaker, Ruud J. W., Ulfman, Laurien H., Ham, Stephanie L., Jeurink, Prescilla, Karaglani, Eva, van IJcken, Wilfred F. J., Manios, Yannis
Publicado 2022

Single-Cell RNA Sequencing of Donor-Reactive T Cells Reveals Role of Apoptosis in Donor-Specific Hyporesponsiveness of Kidney Transplant Recipients

por van der List, Amy C. J., Litjens, Nicolle H. R., Brouwer, Rutger W. W., Klepper, Mariska, den Dekker, Alexander T., van Ijcken, Wilfred F. J., Betjes, Michiel G. H.
Publicado 2023

Heritability and De Novo Mutations in Oesophageal Atresia and Tracheoesophageal Fistula Aetiology

por Brosens, Erwin, Brouwer, Rutger W. W., Douben, Hannie, van Bever, Yolande, Brooks, Alice S., Wijnen, Rene M. H., van IJcken, Wilfred F. J., Tibboel, Dick, Rottier, Robbert J., de Klein, Annelies
Publicado 2021

Zeb2 DNA-Binding Sites in Neuroprogenitor Cells Reveal Autoregulation and Affirm Neurodevelopmental Defects, Including in Mowat-Wilson Syndrome

por Birkhoff, Judith C., Korporaal, Anne L., Brouwer, Rutger W. W., Nowosad, Karol, Milazzo, Claudia, Mouratidou, Lidia, van den Hout, Mirjam C. G. N., van IJcken, Wilfred F. J., Huylebroeck, Danny, Conidi, Andrea
Publicado 2023

Comparative single-cell RNA-sequencing profiling of BMP4-treated primary glioma cultures reveals therapeutic markers

por Verploegh, Iris S C, Conidi, Andrea, Brouwer, Rutger W W, Balcioglu, Hayri E, Karras, Panagiotis, Makhzami, Samira, Korporaal, Anne, Marine, Jean-Christophe, Lamfers, Martine, Van IJcken, Wilfred F J, Leenstra, Sieger, Huylebroeck, Danny
Publicado 2022

Comparison of Mycoplasma pneumoniae Genome Sequences from Strains Isolated from Symptomatic and Asymptomatic Patients

por Spuesens, Emiel B. M., Brouwer, Rutger W. W., Mol, Kristin H. J. M., Hoogenboezem, Theo, Kockx, Christel E. M., Jansen, Ruud, Van IJcken, Wilfred F. J., Van Rossum, Annemarie M. C., Vink, Cornelis
Publicado 2016

CFTR Correctors and Antioxidants Partially Normalize Lipid Imbalance but not Abnormal Basal Inflammatory Cytokine Profile in CF Bronchial Epithelial Cells

por Veltman, Mieke, De Sanctis, Juan B., Stolarczyk, Marta, Klymiuk, Nikolai, Bähr, Andrea, Brouwer, Rutger W., Oole, Edwin, Shah, Juhi, Ozdian, Tomas, Liao, Jie, Martini, Carolina, Radzioch, Danuta, Hanrahan, John W., Scholte, Bob J.
Publicado 2021

Validation of a Combined Transcriptome and T Cell Receptor Alpha/Beta (TRA/TRB) Repertoire Assay at the Single Cell Level for Paucicellular Samples

por Litjens, Nicolle H. R., Langerak, Anton W., van der List, Amy C. J., Klepper, Mariska, de Bie, Maaike, Azmani, Zakia, den Dekker, Alexander T., Brouwer, Rutger W. W., Betjes, Michiel G. H., Van IJcken, Wilfred F. J.
Publicado 2020

Whole-Genome Linkage Scan Combined With Exome Sequencing Identifies Novel Candidate Genes for Carotid Intima-Media Thickness

por Vojinovic, Dina, Kavousi, Maryam, Ghanbari, Mohsen, Brouwer, Rutger W. W., van Rooij, Jeroen G. J., van den Hout, Mirjam C. G. N., Kraaij, Robert, van Ijcken, Wilfred F. J., Uitterlinden, Andre G., van Duijn, Cornelia M., Amin, Najaf
Publicado 2018

Targeted chromatin conformation analysis identifies novel distal neural enhancers of ZEB2 in pluripotent stem cell differentiation

por Birkhoff, Judith C, Brouwer, Rutger W W, Kolovos, Petros, Korporaal, Anne L, Bermejo-Santos, Ana, Boltsis, Ilias, Nowosad, Karol, van den Hout, Mirjam C G N, Grosveld, Frank G, van IJcken, Wilfred F J, Huylebroeck, Danny, Conidi, Andrea
Publicado 2020

Epigenomic analysis of KLF1 haploinsufficiency in primary human erythroblasts

por Heshusius, Steven, Grech, Laura, Gillemans, Nynke, Brouwer, Rutger W. W., den Dekker, Xander T., van IJcken, Wilfred F. J., Nota, Benjamin, Felice, Alex E., van Dijk, Thamar B., von Lindern, Marieke, Borg, Joseph, van den Akker, Emile, Philipsen, Sjaak
Publicado 2022

The detailed 3D multi-loop aggregate/rosette chromatin architecture and functional dynamic organization of the human and mouse genomes

por Knoch, Tobias A., Wachsmuth, Malte, Kepper, Nick, Lesnussa, Michael, Abuseiris, Anis, Ali Imam, A. M., Kolovos, Petros, Zuin, Jessica, Kockx, Christel E. M., Brouwer, Rutger W. W., van de Werken, Harmen J. G., van IJcken, Wilfred F. J., Wendt, Kerstin S., Grosveld, Frank G.
Publicado 2016

NOXA expression drives synthetic lethality to RUNX1 inhibition in pancreatic cancer

por Doffo, Josefina, Bamopoulos, Stefanos A., Köse, Hazal, Orben, Felix, Zang, Chuanbing, Pons, Miriam, den Dekker, Alexander T., Brouwer, Rutger W. W., Baluapuri, Apoorva, Habringer, Stefan, Reichert, Maximillian, Illendula, Anuradha, Krämer, Oliver H., Schick, Markus, Wolf, Elmar, van IJcken, Wilfred F. J., Esposito, Irene, Keller, Ulrich, Schneider, Günter, Wirth, Matthias
Publicado 2022

Exome-Wide Meta-Analysis Identifies Rare 3′-UTR Variant in ERCC1/CD3EAP Associated with Symptoms of Sleep Apnea

por van der Spek, Ashley, Luik, Annemarie I., Kocevska, Desana, Liu, Chunyu, Brouwer, Rutger W. W., van Rooij, Jeroen G. J., van den Hout, Mirjam C. G. N., Kraaij, Robert, Hofman, Albert, Uitterlinden, André G., van IJcken, Wilfred F. J., Gottlieb, Daniel J., Tiemeier, Henning, van Duijn, Cornelia M., Amin, Najaf
Publicado 2017

Unraveling the Genetics of Congenital Diaphragmatic Hernia: An Ongoing Challenge

por Brosens, Erwin, Peters, Nina C. J., van Weelden, Kim S., Bendixen, Charlotte, Brouwer, Rutger W. W., Sleutels, Frank, Bruggenwirth, Hennie T., van Ijcken, Wilfred F. J., Veenma, Danielle C. M., Otter, Suzan C. M. Cochius-Den, Wijnen, Rene M. H., Eggink, Alex J., van Dooren, Marieke F., Reutter, Heiko Martin, Rottier, Robbert J., Schnater, J. Marco, Tibboel, Dick, de Klein, Annelies
Publicado 2022

Exome Sequencing Analysis Identifies Rare Variants in ATM and RPL8 That Are Associated With Shorter Telomere Length

por van der Spek, Ashley, Warner, Sophie C., Broer, Linda, Nelson, Christopher P., Vojinovic, Dina, Ahmad, Shahzad, Arp, Pascal P., Brouwer, Rutger W. W., Denniff, Matthew, van den Hout, Mirjam C. G. N., van Rooij, Jeroen G. J., Kraaij, Robert, van IJcken, Wilfred F. J., Samani, Nilesh J., Ikram, M. Arfan, Uitterlinden, André G., Codd, Veryan, Amin, Najaf, van Duijn, Cornelia M.
Publicado 2020

The tumor suppressor MIR139 is silenced by POLR2M to promote AML oncogenesis

por Stavast, Christiaan J., van Zuijen, Iris, Karkoulia, Elena, Özçelik, Arman, van Hoven-Beijen, Antoinette, Leon, Leticia G., Voerman, Jane S. A., Janssen, George M. C., van Veelen, Peter A., Burocziova, Monika, Brouwer, Rutger W. W., van IJcken, Wilfred F. J., Maas, Alex, Bindels, Eric M., van der Velden, Vincent H. J., Schliehe, Christopher, Katsikis, Peter D., Alberich-Jorda, Meritxell, Erkeland, Stefan J.
Publicado 2021

CRISPRs in the human genome are differentially expressed between malignant and normal adjacent to tumor tissue

por van Riet, Job, Saha, Chinmoy, Strepis, Nikolaos, Brouwer, Rutger W. W., Martens-Uzunova, Elena S., van de Geer, Wesley S., Swagemakers, Sigrid M. A., Stubbs, Andrew, Halimi, Yassir, Voogd, Sanne, Tanmoy, Arif Mohammad, Komor, Malgorzata A., Hoogstrate, Youri, Janssen, Bart, Fijneman, Remond J. A., Niknafs, Yashar S., Chinnaiyan, Arul M., van IJcken, Wilfred F. J., van der Spek, Peter J., Jenster, Guido, Louwen, Rogier
Publicado 2022