Direct Inhibition of β-catenin: A new strategy for colorectal cancer

por Ganesh, Shanthi, Brown, Bob D., Abrams, Marc
Publicado 2019

Therapeutic RNA interference: A novel approach to the treatment of primary hyperoxaluria

por Forbes, Thomas A., Brown, Bob D., Lai, Chengjung
Publicado 2021

Hepatic Lactate Dehydrogenase A: An RNA Interference Target for the Treatment of All Known Types of Primary Hyperoxaluria

por Ariceta, Gema, Barrios, Kelly, Brown, Bob D., Hoppe, Bernd, Rosskamp, Ralf, Langman, Craig B.
Publicado 2021

RNAi-Mediated β-Catenin Inhibition Promotes T Cell Infiltration and Antitumor Activity in Combination with Immune Checkpoint Blockade

por Ganesh, Shanthi, Shui, Xue, Craig, Kevin P., Park, Jihye, Wang, Weimin, Brown, Bob D., Abrams, Marc T.
Publicado 2018

Glutathione and Bcl-2 targeting facilitates elimination by chemoradiotherapy of human A375 melanoma xenografts overexpressing bcl-xl, bcl-2, and mcl-1

por Mena, Salvador, Rodriguez, María L, Ortega, Angel, Priego, Sonia, Obrador, Elena, Asensi, Miguel, Petschen, Ignacio, Cerdá, Miguel, Brown, Bob D, Estrela, José M
Publicado 2012

Specific Inhibition of Hepatic Lactate Dehydrogenase Reduces Oxalate Production in Mouse Models of Primary Hyperoxaluria

por Lai, Chengjung, Pursell, Natalie, Gierut, Jessica, Saxena, Utsav, Zhou, Wei, Dills, Michael, Diwanji, Rohan, Dutta, Chaitali, Koser, Martin, Nazef, Naim, Storr, Rachel, Kim, Boyoung, Martin-Higueras, Cristina, Salido, Eduardo, Wang, Weimin, Abrams, Marc, Dudek, Henryk, Brown, Bob D.
Publicado 2018

Inhibition of Glycogen Synthase II with RNAi Prevents Liver Injury in Mouse Models of Glycogen Storage Diseases

por Pursell, Natalie, Gierut, Jessica, Zhou, Wei, Dills, Michael, Diwanji, Rohan, Gjorgjieva, Monika, Saxena, Utsav, Yang, Jr-Shiuan, Shah, Anee, Venkat, Nandini, Storr, Rachel, Kim, Boyoung, Wang, Weimin, Abrams, Marc, Raffin, Margaux, Mithieux, Gilles, Rajas, Fabienne, Dudek, Henryk, Brown, Bob D., Lai, Chengjung
Publicado 2018

Knockdown of β-catenin with Dicer-Substrate siRNAs Reduces Liver Tumor Burden In vivo

por Dudek, Henryk, Wong, Darren H, Arvan, Rokhand, Shah, Anee, Wortham, Kathleen, Ying, Bo, Diwanji, Rohan, Zhou, Wei, Holmes, Benjamin, Yang, Hailin, Cyr, Wendy A, Zhou, Yi, Shah, Aalok, Farkiwala, Ruchir, Lee, Michael, Li, Yiting, Rettig, Garrett R, Collingwood, Michael A, Basu, Sujit K, Behlke, Mark A, Brown, Bob D
Publicado 2014

Inhibition of Glycolate Oxidase With Dicer-substrate siRNA Reduces Calcium Oxalate Deposition in a Mouse Model of Primary Hyperoxaluria Type 1

por Dutta, Chaitali, Avitahl-Curtis, Nicole, Pursell, Natalie, Larsson Cohen, Marita, Holmes, Benjamin, Diwanji, Rohan, Zhou, Wei, Apponi, Luciano, Koser, Martin, Ying, Bo, Chen, Dongyu, Shui, Xue, Saxena, Utsav, Cyr, Wendy A, Shah, Anee, Nazef, Naim, Wang, Weimin, Abrams, Marc, Dudek, Henryk, Salido, Eduardo, Brown, Bob D, Lai, Chengjung
Publicado 2016