Interrogation of the Pathogen Box reveals small molecule ligands against the mycobacterial trehalose transporter LpqY-SugABC

por Radhakrishnan, Anjana, Brown, Chelsea M., Guy, Collette S., Cooper, Charlotte, Pacheco-Gomez, Raul, Stansfeld, Phillip J., Fullam, Elizabeth
Publicado 2022

Peptidoglycan biosynthesis is driven by lipid transfer along enzyme-substrate affinity gradients

por Oluwole, Abraham O., Corey, Robin A., Brown, Chelsea M., Hernández-Rocamora, Victor M., Stansfeld, Phillip J., Vollmer, Waldemar, Bolla, Jani R., Robinson, Carol V.
Publicado 2022

Structural basis of trehalose recognition by the mycobacterial LpqY-SugABC transporter

por Furze, Christopher M., Delso, Ignacio, Casal, Enriqueta, Guy, Collette S., Seddon, Chloe, Brown, Chelsea M., Parker, Hadyn L., Radhakrishnan, Anjana, Pacheco-Gomez, Raul, Stansfeld, Phillip J., Angulo, Jesus, Cameron, Alexander D., Fullam, Elizabeth
Publicado 2021

Supramolecular organization and dynamics of mannosylated phosphatidylinositol lipids in the mycobacterial plasma membrane

por Brown, Chelsea M., Corey, Robin A., Grélard, Axelle, Gao, Ya, Choi, Yeol Kyo, Luna, Emanuel, Gilleron, Martine, Destainville, Nicolas, Nigou, Jérôme, Loquet, Antoine, Fullam, Elizabeth, Im, Wonpil, Stansfeld, Phillip J., Chavent, Matthieu
Publicado 2023

PLSCR1 is a cell-autonomous defence factor against SARS-CoV-2 infection

por Xu, Dijin, Jiang, Weiqian, Wu, Lizhen, Gaudet, Ryan G., Park, Eui-Soon, Su, Maohan, Cheppali, Sudheer Kumar, Cheemarla, Nagarjuna R., Kumar, Pradeep, Uchil, Pradeep D., Grover, Jonathan R., Foxman, Ellen F., Brown, Chelsea M., Stansfeld, Phillip J., Bewersdorf, Joerg, Mothes, Walther, Karatekin, Erdem, Wilen, Craig B., MacMicking, John D.
Publicado 2023

Structural basis of peptidoglycan synthesis by E. coli RodA-PBP2 complex

por Nygaard, Rie, Graham, Chris L. B., Belcher Dufrisne, Meagan, Colburn, Jonathan D., Pepe, Joseph, Hydorn, Molly A., Corradi, Silvia, Brown, Chelsea M., Ashraf, Khuram U., Vickery, Owen N., Briggs, Nicholas S., Deering, John J., Kloss, Brian, Botta, Bruno, Clarke, Oliver B., Columbus, Linda, Dworkin, Jonathan, Stansfeld, Phillip J., Roper, David I., Mancia, Filippo
Publicado 2023