Searching for novel cell cycle regulators in Trypanosoma brucei with an RNA interference screen

por Monnerat, Séverine, Clucas, Caroline, Brown, Elaine, Mottram, Jeremy C, Hammarton, Tansy C
Publicado 2009

An Essential Signal Peptide Peptidase Identified in an RNAi Screen of Serine Peptidases of Trypanosoma brucei

por Moss, Catherine X., Brown, Elaine, Hamilton, Alana, Van der Veken, Pieter, Augustyns, Koen, Mottram, Jeremy C.
Publicado 2015

Conditional gene deletion with DiCre demonstrates an essential role for CRK3 in L eishmania mexicana cell cycle regulation

por Duncan, Samuel M., Myburgh, Elmarie, Philipon, Cintia, Brown, Elaine, Meissner, Markus, Brewer, James, Mottram, Jeremy C.
Publicado 2016

Control of protein palmitoylation by regulating substrate recruitment to a zDHHC-protein acyltransferase

por Plain, Fiona, Howie, Jacqueline, Kennedy, Jennifer, Brown, Elaine, Shattock, Michael J., Fraser, Niall J., Fuller, William
Publicado 2020

Regulators of Trypanosoma brucei Cell Cycle Progression and Differentiation Identified Using a Kinome-Wide RNAi Screen

por Jones, Nathaniel G., Thomas, Elizabeth B., Brown, Elaine, Dickens, Nicholas J., Hammarton, Tansy C., Mottram, Jeremy C.
Publicado 2014

Biomarkers of exposure and potential harm in exclusive users of electronic cigarettes and current, former, and never smokers

por Haswell, Linsey E., Gale, Nathan, Brown, Elaine, Azzopardi, David, McEwan, Michael, Thissen, Jesse, Meichanetzidis, Filimon, Hardie, George
Publicado 2023

The role of the multidisciplinary team in the management of deep infiltrating endometriosis

por Ugwumadu, Lilian, Chakrabarti, Rima, Williams-Brown, Elaine, Rendle, John, Swift, Ian, John, Babbin, Allen-Coward, Heather, Ofuasia, Emmanuel
Publicado 2017

Posttraumatic Stress Disorder and Mobile Health: App Investigation and Scoping Literature Review

por Rodriguez-Paras, Carolina, Tippey, Kathryn, Brown, Elaine, Sasangohar, Farzan, Creech, Suzannah, Kum, Hye-Chung, Lawley, Mark, Benzer, Justin K
Publicado 2017

Palmitoylation regulates the magnitude of HCN4-mediated currents in mammalian cells

por Congreve, Samitha Dilini, Main, Alice, Butler, Andrew S., Gao, Xing, Brown, Elaine, Du, Chunyun, Choisy, Stephanié C., Cheng, Hongwei, Hancox, Jules C., Fuller, William
Publicado 2023

Essential roles for deubiquitination in Leishmania life cycle progression

por Damianou, Andreas, Burge, Rebecca J., Catta-Preta, Carolina M. C., Geoghegan, Vincent, Nievas, Y. Romina, Newling, Katherine, Brown, Elaine, Burchmore, Richard, Rodenko, Boris, Mottram, Jeremy C.
Publicado 2020

High Throughput Screens Yield Small Molecule Inhibitors of Leishmania CRK3:CYC6 Cyclin-Dependent Kinase

por Walker, Roderick G., Thomson, Graeme, Malone, Kirk, Nowicki, Matthew W., Brown, Elaine, Blake, David G., Turner, Nicholas J., Walkinshaw, Malcolm D., Grant, Karen M., Mottram, Jeremy C.
Publicado 2011

PNT1 Is a C11 Cysteine Peptidase Essential for Replication of the Trypanosome Kinetoplast

por Grewal, Jaspreet S., McLuskey, Karen, Das, Debanu, Myburgh, Elmarie, Wilkes, Jonathan, Brown, Elaine, Lemgruber, Leandro, Gould, Matthew K., Burchmore, Richard J., Coombs, Graham H., Schnaufer, Achim, Mottram, Jeremy C.
Publicado 2016

ATR Inhibitor AZD6738 (Ceralasertib) Exerts Antitumor Activity as a Monotherapy and in Combination with Chemotherapy and the PARP Inhibitor Olaparib

por Wilson, Zena, Odedra, Rajesh, Wallez, Yann, Wijnhoven, Paul W.G., Hughes, Adina M., Gerrard, Joe, Jones, Gemma N., Bargh-Dawson, Hannah, Brown, Elaine, Young, Lucy A., O'Connor, Mark J., Lau, Alan
Publicado 2022

A Leishmania infantum genetic marker associated with miltefosine treatment failure for visceral leishmaniasis

por Carnielli, Juliana B.T., Crouch, Kathryn, Forrester, Sarah, Silva, Vladimir Costa, Carvalho, Sílvio F.G., Damasceno, Jeziel D., Brown, Elaine, Dickens, Nicholas J., Costa, Dorcas L., Costa, Carlos H.N., Dietze, Reynaldo, Jeffares, Daniel C., Mottram, Jeremy C.
Publicado 2018

Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors

por Saldivia, Manuel, Fang, Eric, Ma, Xiaolei, Myburgh, Elmarie, Carnielli, Juliana B. T., Bower-Lepts, Christopher, Brown, Elaine, Ritchie, Ryan, Lakshminarayana, Suresh B., Chen, Yen-Liang, Patra, Debjani, Ornelas, Elizabeth, Koh, Hazel X. Y., Williams, Sarah, Supek, Frantisek, Paape, Daniel, McCulloch, Richard, Kaiser, Marcel, Barrett, Michael P., Jiricek, Jan, Diagana, Thierry T., Mottram, Jeremy C., Rao, Srinivasa P.S.
Publicado 2020