Sphingosine 1-phosphate receptor 3 and RhoA signaling mediate inflammatory gene expression in astrocytes

por Dusaban, Stephanie S., Chun, Jerold, Rosen, Hugh, Purcell, Nicole H., Brown, Joan Heller
Publicado 2017

Identification of Potential Small Molecule Binding Pockets on Rho Family GTPases

por Ortiz-Sanchez, Juan Manuel, Nichols, Sara E., Sayyah, Jacqueline, Brown, Joan Heller, McCammon, J. Andrew, Grant, Barry J.
Publicado 2012

Novel Allosteric Sites on Ras for Lead Generation

por Grant, Barry J., Lukman, Suryani, Hocker, Harrison J., Sayyah, Jaqueline, Brown, Joan Heller, McCammon, J. Andrew, Gorfe, Alemayehu A.
Publicado 2011

RhoA signaling increases mitophagy and protects cardiomyocytes against ischemia by stabilizing PINK1 protein and recruiting Parkin to mitochondria

por Tu, Michelle, Tan, Valerie P., Yu, Justin D., Tripathi, Raghav, Bigham, Zahna, Barlow, Melissa, Smith, Jeffrey M., Brown, Joan Heller, Miyamoto, Shigeki
Publicado 2022

Nitric Oxide modulates spontaneous Ca(2+) release and ventricular arrhythmias during β-adrenergic signalling through S-nitrosylation of Calcium/Calmodulin dependent kinase II

por Power, Amelia S., Asamudo, Esther, Worthington, Luke P. I., Alim, Chidera C., Parackal, Raquel, Wallace, Rachel S., Ebenebe, Obialunanma V., Brown, Joan Heller, Kohr, Mark J., Bers, Donald M., Erickson, Jeffrey R.
Publicado 2023

Co‐occurrence of BAP1 and SF3B1 mutations in uveal melanoma induces cellular senescence

por Yu, Le, Zhou, Dan, Zhang, Guiming, Ren, Zhonglu, Luo, Xin, Liu, Peng, Plouffe, Steven W., Meng, Zhipeng, Moroishi, Toshiro, Li, Yilei, Zhang, Yiyue, Brown, Joan Heller, Liu, Shuwen, Guan, Kun‐Liang
Publicado 2021

YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity

por Yu, Olivia M, Benitez, Jorge A, Plouffe, Steven W, Ryback, Daniel, Klein, Andrea, Smith, Jeff, Greenbaum, Jason, Delatte, Benjamin, Rao, Anjana, Guan, Kun-Liang, Furnari, Frank B, Chaim, Olga Meiri, Miyamoto, Shigeki, Brown, Joan Heller
Publicado 2018

Akt regulates L-type Ca(2+) channel activity by modulating Ca(v)α1 protein stability

por Catalucci, Daniele, Zhang, Deng-Hong, DeSantiago, Jaime, Aimond, Franck, Barbara, Guillaume, Chemin, Jean, Bonci, Désiré, Picht, Eckard, Rusconi, Francesca, Dalton, Nancy D., Peterson, Kirk L., Richard, Sylvain, Bers, Donald M., Brown, Joan Heller, Condorelli, Gianluigi
Publicado 2009

Akt regulates L-type Ca(2+) channel activity by modulating Ca(v)α1 protein stability

por Catalucci, Daniele, Zhang, Deng-Hong, DeSantiago, Jaime, Aimond, Franck, Barbara, Guillaume, Chemin, Jean, Bonci, Désiré, Picht, Eckard, Rusconi, Francesca, Dalton, Nancy D., Peterson, Kirk L., Richard, Sylvain, Bers, Donald M., Brown, Joan Heller, Condorelli, Gianluigi
Publicado 2013

APJ ACTS AS A DUAL RECEPTOR IN CARDIAC HYPERTROPHY

por Scimia, Maria Cecilia, Hurtado, Cecilia, Ray, Saugata, Metzler, Scott, Wei, Ke, Wang, Jianming, Woods, Chris E., Purcell, Nicole H., Catalucci, Daniele, Akasaka, Takashi, Bueno, Orlando F., Vlasuk, George P., Kaliman, Perla, Bodmer, Rolf, Smith, Layton H., Ashley, Euan, Mercola, Mark, Brown, Joan Heller, Ruiz-Lozano, Pilar
Publicado 2012

CaMKIIδC Drives Early Adaptive Ca(2+) Change and Late Eccentric Cardiac Hypertrophy

por Ljubojevic-Holzer, Senka, Herren, Anthony W., Djalinac, Natasa, Voglhuber, Julia, Morotti, Stefano, Holzer, Michael, Wood, Brent M., Abdellatif, Mahmoud, Matzer, Ingrid, Sacherer, Michael, Radulovic, Snjezana, Wallner, Markus, Ivanov, Milan, Wagner, Stefan, Sossalla, Samuel, von Lewinski, Dirk, Pieske, Burkert, Brown, Joan Heller, Sedej, Simon, Bossuyt, Julie, Bers, Donald M.
Publicado 2020