Obese Adipose Tissue as a Driver of Breast Cancer Growth and Development: Update and Emerging Evidence

por Bhardwaj, Priya, Brown, Kristy A.
Publicado 2021

Targeting obesity-related dysfunction in hormonally driven cancers

por Rubinstein, Maria M., Brown, Kristy A., Iyengar, Neil M.
Publicado 2021

Ghrelin and Breast Cancer: Emerging Roles in Obesity, Estrogen Regulation, and Cancer

por Au, CheukMan Cherie, Furness, John B., Brown, Kristy A.
Publicado 2017

Facts and Perspectives: Implications of tumor glycolysis on immunotherapy response in triple negative breast cancer

por Schreier, Ashley, Zappasodi, Roberta, Serganova, Inna, Brown, Kristy A., Demaria, Sandra, Andreopoulou, Eleni
Publicado 2023

SAT-126 Breast Adipose Tissue Extracellular Vesicles from Obese Women Increase Breast Cancer Aggressiveness - a Novel Mechanism for the Obesity-Breast Cancer Link

por Benito-Martin, Alberto, Paik, Paul, Mushannen, Malik, Bhardwaj, Priya, Oshchepkova, Sonya, Spector, Jason, Brown, Kristy A
Publicado 2020

Dysregulated metabolism and the regulation of aromatase in breast adipose stromal cells in obesity and cancer

por Samarajeewa, Nirukshi U, Yang, Fangyuan, Docanto, Maria, Sakurai, Minako, Sasano, Hironobu, Simpson, Evan R, Brown, Kristy A
Publicado 2012

FRI026 PPARγ Antagonists Induce Aromatase Transcription In Human Adipose Tissue Cells

por Ardenkjær-Skinnerup, Jacob, Petersen, Patricia S S, Hadrup, Niels, Ravn-Haren, Gitte, Emanuelli, Brice, Vogel, Ulla B, Brown, Kristy A
Publicado 2023

Abstract 138: Interrogating the Metabolic Interactions Between Adipocytes and Breast Cancer in a Patient-Derived Tissue Engineered Platform--Implications for the Safety of Autologo...

por Toyoda, Yoshiko, Celie, Karel-Bart, Buro, Justin, Lin, Alexandra, Xu, Jonathan, Miller, Andrew, Morgan, John, Brown, Kristy A., Spector, Jason A.
Publicado 2018

Abstract 56: A Patient Specific Tissue Engineered Biomimetic Platform For High Throughput Analysis Of Breast Cancer Therapeutic Options

por Toyoda, Yoshiko, Celie, Karel-Bart, Buro, Justin, Lin, Alexandra, Xu, Jonathan, Abadeer, Andrew, Jin, Julia, Morgan, John, Brown, Kristy A., Spector, Jason A.
Publicado 2018

Abstract 125: Silicone Implant Shells Increase The Rate Of Proliferation Of Patient-derived BIA-ALCL Cells But Not Primary T Cells In An Engineered Biomimetic Patient-derived Breas...

por Premaratne, Ishani D., Wright, Matthew A., Gadjiko, Mariam, Lara, Daniel O., Samadi, Arash, Ginter, Paula S., Inghirami, Giorgio, Brown, Kristy A., Spector, Jason A.
Publicado 2020

Abstract 11: A Novel Tissue Engineered Three-Dimensional Biomimetic Platform for In Vitro Study of BIA-ALCL

por Wright, Matthew A., Lara, Daniel O., Samadi, Arash, Toyoda, Yoshiko, Celie, Karel-Bart, Zhao, Runlei, Inghirami, Giorgio G., Brown, Kristy A., Spector, Jason A.
Publicado 2019

HIF-1α stimulates aromatase expression driven by prostaglandin E(2 )in breast adipose stroma

por Samarajeewa, Nirukshi U, Yang, Fangyuan, Docanto, Maria M, Sakurai, Minako, McNamara, Keely M, Sasano, Hironobu, Fox, Stephen B, Simpson, Evan R, Brown, Kristy A
Publicado 2013

Exploring the Effect of Implant Shell on Patient-derived Breast Implant–associated Anaplastic Large Cell Lymphoma Cells in Ex Vivo Biomimetic Breast Tissue

por Wright, Matthew A., Lara, Daniel O., Fiore, Danilo, Zhao, Runlei, Samadi, Arash, Celie, Karel-Bart, Toyoda, Yoshi, Inghirami, Giorgio, Brown, Kristy A., Spector, Jason A.
Publicado 2019

Silicone Implant Shells Increase the Rate of Proliferation of Alk- but Not Alk+ Lymphoma Cells in an Engineered Biomimetic Breast Microenvironment

por Premaratne, Ishani D., Wright, Matthew A., Gadjiko, Mariam, Dong, Xue, Samadi, Arash, Lara, Daniel O., Berri, Nabih, Ginter, Paula S., Inghirami, Giorgio, Brown, Kristy A., Spector, Jason A.
Publicado 2020

Leptin regulation of the p53-HIF1α/PKM2-aromatase axis in breast adipose stromal cells – a novel mechanism for the obesity-breast cancer link

por Zahid, Heba, Subbaramaiah, Kotha, Iyengar, Neil M., Zhou, Xi Kathy, Chen, I-Chun, Bhardwaj, Priya, Gucalp, Ayca, Morrow, Monica, Hudis, Clifford A., Dannenberg, Andrew J., Brown, Kristy A.
Publicado 2017

No effect of unacylated ghrelin administration on subcutaneous PC3 xenograft growth or metabolic parameters in a Rag1(-/-) mouse model of metabolic dysfunction

por Maugham, Michelle L., Seim, Inge, Thomas, Patrick B., Crisp, Gabrielle J., Shah, Esha T., Herington, Adrian C., Brown, Kristy A., Gregory, Laura S., Nelson, Colleen C., Jeffery, Penny L., Chopin, Lisa K.
Publicado 2018

Sex-steroid hormones and risk of postmenopausal estrogen receptor-positive breast cancer: a case-cohort analysis

por Albers, Frances EM, Lou, Makayla WC, Dashti, S Ghazaleh, Swain, Christopher TV, Rinaldi, Sabina, Viallon, Vivian, Karahalios, Amalia, Brown, Kristy A, Gunter, Marc J, Milne, Roger L, English, Dallas R, Lynch, Brigid M
Publicado 2023

High mammographic density is associated with an increase in stromal collagen and immune cells within the mammary epithelium

por Huo, Cecilia W., Chew, Grace, Hill, Prue, Huang, Dexing, Ingman, Wendy, Hodson, Leigh, Brown, Kristy A., Magenau, Astrid, Allam, Amr H., McGhee, Ewan, Timpson, Paul, Henderson, Michael A., Thompson, Erik W., Britt, Kara
Publicado 2015

Linking Physical Activity to Breast Cancer: Text Mining Results and a Protocol for Systematically Reviewing Three Potential Mechanistic Pathways

por Lynch, Brigid M., Milne, Roger L., English, Dallas R., Brown, Kristy A., Drummond, Ann E., Swain, Christopher T.V., van Roekel, Eline H., Moore, Melissa M., Gaunt, Tom R., Martin, Richard M., Lewis, Sarah J.
Publicado 2022

Linking Physical Activity to Breast Cancer via Sex Steroid Hormones, Part 2: The Effect of Sex Steroid Hormones on Breast Cancer Risk

por Drummond, Ann E., Swain, Christopher T.V., Brown, Kristy A., Dixon-Suen, Suzanne C., Boing, Leonessa, van Roekel, Eline H., Moore, Melissa M., Gaunt, Tom R., Milne, Roger L., English, Dallas R., Martin, Richard M., Lewis, Sarah J., Lynch, Brigid M.
Publicado 2022