Defining and navigating macrocycle chemical space

por Viarengo-Baker, Lauren A., Brown, Lauren E., Rzepiela, Anna A., Whitty, Adrian
Publicado 2021

Condensation tendency and planar isotropic actin gradient induce radial alignment in confined monolayers

por Xie, Tianfa, St Pierre, Sarah R, Olaranont, Nonthakorn, Brown, Lauren E, Wu, Min, Sun, Yubing
Publicado 2021

Neighborhood cohesion and psychological distress across race and sexual orientation

por Miller, Gabe H., Marquez-Velarde, Guadalupe, Lindstrom, Erika-Danielle, Keith, Verna M., Brown, Lauren E.
Publicado 2022

Sensitization of renal carcinoma cells to TRAIL-induced apoptosis by rocaglamide and analogs

por Nalli, Ancy D., Brown, Lauren E., Thomas, Cheryl L., Sayers, Thomas J., Porco, John A., Henrich, Curtis J.
Publicado 2018

Translation Inhibition by Rocaglates Activates a Species-Specific Cell Death Program in the Emerging Fungal Pathogen Candida auris

por Iyer, Kali R., Whitesell, Luke, Porco, John A., Henkel, Thomas, Brown, Lauren E., Robbins, Nicole, Cowen, Leah E.
Publicado 2020

Patients’ Perceived Level of Clinician Knowledge of Transgender Health Care, Self-rated Health, and Psychological Distress Among Transgender Adults

por Miller, Gabe H., Marquez-Velarde, Guadalupe, Mills, Alex R., Hernandez, Stephanie M., Brown, Lauren E., Mustafa, Mudasir, Shircliff, Jesse E.
Publicado 2023

A Novel Class of Small Molecule Compounds that Inhibit Hepatitis C Virus Infection by Targeting the Prohibitin-CRaf Pathway

por Liu, Shufeng, Wang, Wenyu, Brown, Lauren E., Qiu, Chao, Lajkiewicz, Neil, Zhao, Ting, Zhou, Jianhua, Porco, John A., Wang, Tony T.
Publicado 2015

Intersexuality and the Cricket Frog Decline: Historic and Geographic Trends

por Reeder, Amy L., Ruiz, Marilyn O., Pessier, Allan, Brown, Lauren E., Levengood, Jeffrey M., Phillips, Christopher A., Wheeler, Matthew B., Warner, Richard E., Beasley, Val R.
Publicado 2005

Oxo-aglaiastatin-Mediated Inhibition of Translation Initiation

por Itoua Maïga, Rayelle, Cencic, Regina, Chu, Jennifer, Waller, Daniel D., Brown, Lauren E., Devine, William G., Zhang, Wenhan, Sebag, Michael, Porco Jr., John A., Pelletier, Jerry
Publicado 2019

Rocaglates Induce Gain-of-Function Alterations to eIF4A and eIF4F

por Chu, Jennifer, Zhang, Wenhan, Cencic, Regina, O’Connor, Patrick B.F., Robert, Francis, Devine, William G., Selznick, Asher, Henkel, Thomas, Merrick, William C., Brown, Lauren E., Baranov, Pavel V., Porco, John A., Pelletier, Jerry
Publicado 2020

Channeling macrophage polarization by rocaglates increases macrophage resistance to Mycobacterium tuberculosis

por Chatterjee, Sujoy, Yabaji, Shivraj M., Rukhlenko, Oleksii S., Bhattacharya, Bidisha, Waligurski, Emily, Vallavoju, Nandini, Ray, Somak, Kholodenko, Boris N., Brown, Lauren E., Beeler, Aaron B., Ivanov, Alexander R., Kobzik, Lester, Porco, John A., Kramnik, Igor
Publicado 2021

Targeting Translation Initiation by Synthetic Rocaglates for Treating MYC-driven Lymphomas

por Zhang, Xuan, Bi, Chengfeng, Lu, Ting, Zhang, Weiwei, Yue, Ting, Wang, Cheng, Tian, Tian, Zhang, Xiaoyan, Huang, Yuhua, Lunning, Matthew, Hao, Xinbao, Brown, Lauren E., Devine, William G., Vose, Julie, Porco, John A., Fu, Kai
Publicado 2019

Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer

por Levi-Galibov, Oshrat, Lavon, Hagar, Wassermann-Dozorets, Rina, Pevsner-Fischer, Meirav, Mayer, Shimrit, Wershof, Esther, Stein, Yaniv, Brown, Lauren E., Zhang, Wenhan, Friedman, Gil, Nevo, Reinat, Golani, Ofra, Katz, Lior H., Yaeger, Rona, Laish, Ido, Porco, John A., Sahai, Erik, Shouval, Dror S., Kelsen, David, Scherz-Shouval, Ruth
Publicado 2020

eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma

por Chan, Karina, Robert, Francis, Oertlin, Christian, Kapeller-Libermann, Dana, Avizonis, Daina, Gutierrez, Johana, Handly-Santana, Abram, Doubrovin, Mikhail, Park, Julia, Schoepfer, Christina, Da Silva, Brandon, Yao, Melissa, Gorton, Faith, Shi, Junwei, Thomas, Craig J., Brown, Lauren E., Porco, John A., Pollak, Michael, Larsson, Ola, Pelletier, Jerry, Chio, Iok In Christine
Publicado 2019

Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus

por Whitesell, Luke, Robbins, Nicole, Huang, David S., McLellan, Catherine A., Shekhar-Guturja, Tanvi, LeBlanc, Emmanuelle V., Nation, Catherine S., Hui, Raymond, Hutchinson, Ashley, Collins, Cathy, Chatterjee, Sharanya, Trilles, Richard, Xie, Jinglin L., Krysan, Damian J., Lindquist, Susan, Porco, John A., Tatu, Utpal, Brown, Lauren E., Pizarro, Juan, Cowen, Leah E.
Publicado 2019

An oxindole efflux inhibitor potentiates azoles and impairs virulence in the fungal pathogen Candida auris

por Iyer, Kali R., Camara, Kaddy, Daniel-Ivad, Martin, Trilles, Richard, Pimentel-Elardo, Sheila M., Fossen, Jen L., Marchillo, Karen, Liu, Zhongle, Singh, Shakti, Muñoz, José F., Kim, Sang Hu, Porco, John A., Cuomo, Christina A., Williams, Noelle S., Ibrahim, Ashraf S., Edwards, John E., Andes, David R., Nodwell, Justin R., Brown, Lauren E., Whitesell, Luke, Robbins, Nicole, Cowen, Leah E.
Publicado 2020

BRCA mutational status shapes the stromal microenvironment of pancreatic cancer linking clusterin expression in cancer associated fibroblasts with HSF1 signaling

por Shaashua, Lee, Ben-Shmuel, Aviad, Pevsner-Fischer, Meirav, Friedman, Gil, Levi-Galibov, Oshrat, Nandakumar, Subhiksha, Barki, Debra, Nevo, Reinat, Brown, Lauren E., Zhang, Wenhan, Stein, Yaniv, Lior, Chen, Kim, Han Sang, Bojmar, Linda, Jarnagin, William R., Lecomte, Nicolas, Mayer, Shimrit, Stok, Roni, Bishara, Hend, Hamodi, Rawand, Levy-Lahad, Ephrat, Golan, Talia, Porco, John A., Iacobuzio-Donahue, Christine A., Schultz, Nikolaus, Tuveson, David A., Lyden, David, Kelsen, David, Scherz-Shouval, Ruth
Publicado 2022

Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space

por Kearney, Sara E., Zahoránszky-Kőhalmi, Gergely, Brimacombe, Kyle R., Henderson, Mark J., Lynch, Caitlin, Zhao, Tongan, Wan, Kanny K., Itkin, Zina, Dillon, Christopher, Shen, Min, Cheff, Dorian M., Lee, Tobie D., Bougie, Danielle, Cheng, Ken, Coussens, Nathan P., Dorjsuren, Dorjbal, Eastman, Richard T., Huang, Ruili, Iannotti, Michael J., Karavadhi, Surendra, Klumpp-Thomas, Carleen, Roth, Jacob S., Sakamuru, Srilatha, Sun, Wei, Titus, Steven A., Yasgar, Adam, Zhang, Ya-Qin, Zhao, Jinghua, Andrade, Rodrigo B., Brown, M. Kevin, Burns, Noah Z., Cha, Jin K., Mevers, Emily E., Clardy, Jon, Clement, Jason A., Crooks, Peter A., Cuny, Gregory D., Ganor, Jake, Moreno, Jesus, Morrill, Lucas A., Picazo, Elias, Susick, Robert B., Garg, Neil K., Goess, Brian C., Grossman, Robert B., Hughes, Chambers C., Johnston, Jeffrey N., Joullie, Madeleine M., Kinghorn, A. Douglas, Kingston, David G.I., Krische, Michael J., Kwon, Ohyun, Maimone, Thomas J., Majumdar, Susruta, Maloney, Katherine N., Mohamed, Enas, Murphy, Brian T., Nagorny, Pavel, Olson, David E., Overman, Larry E., Brown, Lauren E., Snyder, John K., Porco, John A., Rivas, Fatima, Ross, Samir A., Sarpong, Richmond, Sharma, Indrajeet, Shaw, Jared T., Xu, Zhengren, Shen, Ben, Shi, Wei, Stephenson, Corey R.J., Verano, Alyssa L., Tan, Derek S., Tang, Yi, Taylor, Richard E., Thomson, Regan J., Vosburg, David A., Wu, Jimmy, Wuest, William M., Zakarian, Armen, Zhang, Yufeng, Ren, Tianjing, Zuo, Zhong, Inglese, James, Michael, Sam, Simeonov, Anton, Zheng, Wei, Shinn, Paul, Jadhav, Ajit, Boxer, Matthew B., Hall, Matthew D., Xia, Menghang, Guha, Rajarshi, Rohde, Jason M.
Publicado 2018