Analysis of cellular kinetic models suggest that physiologically based model parameters may be inherently, practically unidentifiable

por Brown, Liam V., Coles, Mark C., McConnell, Mark, Ratushny, Alexander V., Gaffney, Eamonn A.
Publicado 2022

Predicted limited redistribution of T cells to secondary lymphoid tissue correlates with increased risk of haematological malignancies in asplenic patients

por Kmieciak, Aleksandra E., Brown, Liam V., Coles, Mark C., Wagg, Jonathan, Phipps, Alex, Gaffney, Eamonn A.
Publicado 2021

De-risking clinical trial failure through mechanistic simulation

por Brown, Liam V, Wagg, Jonathan, Darley, Rachel, van Hateren, Andy, Elliott, Tim, Gaffney, Eamonn A, Coles, Mark C
Publicado 2022

CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson’s disease

por Bengoa-Vergniory, Nora, Faggiani, Emilie, Ramos-Gonzalez, Paula, Kirkiz, Ecem, Connor-Robson, Natalie, Brown, Liam V., Siddique, Ibrar, Li, Zizheng, Vingill, Siv, Cioroch, Milena, Cavaliere, Fabio, Threlfell, Sarah, Roberts, Bradley, Schrader, Thomas, Klärner, Frank-Gerrit, Cragg, Stephanie, Dehay, Benjamin, Bitan, Gal, Matute, Carlos, Bezard, Erwan, Wade-Martins, Richard
Publicado 2020