GVHD Pathogenesis, Prevention and Treatment: Lessons From Humanized Mouse Transplant Models

por Hess, Nicholas J., Brown, Matthew E., Capitini, Christian M.
Publicado 2021

The Immunoregulatory Role of the Signal Regulatory Protein Family and CD47 Signaling Pathway in Type 1 Diabetes

por Sharp, Robert C., Brown, Matthew E., Shapiro, Melanie R., Posgai, Amanda L., Brusko, Todd M.
Publicado 2021

Modeling cell-mediated immunity in human type 1 diabetes by engineering autoreactive CD8(+) T cells

por Peters, Leeana D., Yeh, Wen-I, Arnoletti, Juan M., Brown, Matthew E., Posgai, Amanda L., Mathews, Clayton E., Brusko, Todd M.
Publicado 2023

Nonirradiated NOD,B6.SCID Il2rγ(−/−)Kit(W41/W41) (NBSGW) Mice Support Multilineage Engraftment of Human Hematopoietic Cells

por McIntosh, Brian E., Brown, Matthew E., Duffin, Bret M., Maufort, John P., Vereide, David T., Slukvin, Igor I., Thomson, James A.
Publicado 2015

Genetic Engineering of Immune Evasive Stem Cell-Derived Islets

por Sackett, Sara D., Kaplan, Samuel J., Mitchell, Samantha A., Brown, Matthew E., Burrack, Adam L., Grey, Shane, Huangfu, Danwei, Odorico, Jon
Publicado 2022

Derivation of Induced Pluripotent Stem Cells from Human Peripheral Blood T Lymphocytes

por Brown, Matthew E., Rondon, Elizabeth, Rajesh, Deepika, Mack, Amanda, Lewis, Rachel, Feng, Xuezhu, Zitur, Laura Jo, Learish, Randall D., Nuwaysir, Emile F.
Publicado 2010

Treg-Specific CD226 Deletion Reduces Diabetes Incidence in NOD Mice by Improving Regulatory T-Cell Stability

por Thirawatananond, Puchong, Brown, Matthew E., Sachs, Lindsey K., Arnoletti, Juan M., Yeh, Wen-I, Posgai, Amanda L., Shapiro, Melanie R., Chen, Yi-Guang, Brusko, Todd M.
Publicado 2023

Extracellular matrix scaffold and hydrogel derived from decellularized and delipidized human pancreas

por Sackett, Sara Dutton, Tremmel, Daniel M., Ma, Fengfei, Feeney, Austin K., Maguire, Rachel M., Brown, Matthew E., Zhou, Ying, Li, Xiang, O’Brien, Cori, Li, Lingjun, Burlingham, William J., Odorico, Jon S.
Publicado 2018

A Humanized Mouse Model Generated Using Surplus Neonatal Tissue

por Brown, Matthew E., Zhou, Ying, McIntosh, Brian E., Norman, Ian G., Lou, Hannah E., Biermann, Mitch, Sullivan, Jeremy A., Kamp, Timothy J., Thomson, James A., Anagnostopoulos, Petros V., Burlingham, William J.
Publicado 2018

A Human Pluripotent Stem Cell-Based Screen for Smooth Muscle Cell Differentiation and Maturation Identifies Inhibitors of Intimal Hyperplasia

por Zhang, Jue, McIntosh, Brian E., Wang, Bowen, Brown, Matthew E., Probasco, Mitchell D., Webster, Sarah, Duffin, Bret, Zhou, Ying, Guo, Lian-Wang, Burlingham, William J., Kent, Craig, Ferris, Michael, Thomson, James A.
Publicado 2019

Generation of anti-GD2 CAR macrophages from human pluripotent stem cells for cancer immunotherapies

por Zhang, Jue, Webster, Sarah, Duffin, Bret, Bernstein, Matthew N., Steill, John, Swanson, Scott, Forsberg, Matthew H., Bolin, Jennifer, Brown, Matthew E., Majumder, Aditi, Capitini, Christian M., Stewart, Ron, Thomson, James A., Slukvin, Igor I.
Publicado 2023

Major Histocompatibility Complex–Matched Arteries Have Similar Patency to Autologous Arteries in a Mauritian Cynomolgus Macaque Major Histocompatibility Complex–Defined Transplant...

por Maufort, John P., Israel, Jacqueline S., Brown, Matthew E., Kempton, Steve J., Albano, Nicholas J., Zeng, Weifeng, Kelnhofer, Laurel E., Reynolds, Matthew R., Perrin, Elizabeth S., Sanchez, Ruston J., Sluvkin, Igor I., Thomson, James A., Poore, Samuel O.
Publicado 2019

Human CD4(+)CD25(+)CD226(-) Tregs Demonstrate Increased Purity, Lineage Stability, and Suppressive Capacity Versus CD4(+)CD25(+)CD127(lo/-) Tregs for Adoptive Cell Therapy

por Brown, Matthew E., Peters, Leeana D., Hanbali, Seif R., Arnoletti, Juan M., Sachs, Lindsey K., Nguyen, Kayla Q., Carpenter, Emma B., Seay, Howard R., Fuhrman, Christopher A., Posgai, Amanda L., Shapiro, Melanie R., Brusko, Todd M.
Publicado 2022