Platt versus Pickering: what molecular insight to primary hyperaldosteronism tells us about hypertension

por Brown, Morris J
Publicado 2012

What Do Beta-Blockers Really Do? A View from Both Sides of the Receptor: Based on the Oliver Sharpey Lecture 1992

por Brown, Morris J
Publicado 1993

Nuclear imaging in the diagnosis of primary aldosteronism

por Powlson, Andrew S., Gurnell, Mark, Brown, Morris J.
Publicado 2015

Primary aldosteronism: molecular medicine meets public health

por Azizan, Elena A. B., Drake, William M., Brown, Morris J.
Publicado 2023

Gating defects of disease-causing de novo mutations in Ca(v)1.3 Ca(2+) channels

por Pinggera, Alexandra, Negro, Giulia, Tuluc, Petronel, Brown, Morris J., Lieb, Andreas, Striessnig, Jörg
Publicado 2018

Does offering an incentive payment improve recruitment to clinical trials and increase the proportion of socially deprived and elderly participants?

por Jennings, Claudine G, MacDonald, Thomas M, Wei, Li, Brown, Morris J, McConnachie, Lewis, Mackenzie, Isla S
Publicado 2015

Transcriptome Pathway Analysis of Pathological and Physiological Aldosterone-Producing Human Tissues

por Zhou, Junhua, Lam, Brian, Neogi, Sudeshna G., Yeo, Giles S.H., Azizan, Elena A.B., Brown, Morris J.
Publicado 2016

ANO4 (Anoctamin 4) Is a Novel Marker of Zona Glomerulosa That Regulates Stimulated Aldosterone Secretion

por Maniero, Carmela, Scudieri, Paolo, Haris Shaikh, Lalarukh, Zhao, Wanfeng, Gurnell, Mark, Galietta, Luis J.V., Brown, Morris J.
Publicado 2019

Preclinical and Early Clinical Profile of a Highly Selective and Potent Oral Inhibitor of Aldosterone Synthase (CYP11B2)

por Bogman, Katrijn, Schwab, Dietmar, Delporte, Marie-Laure, Palermo, Giuseppe, Amrein, Kurt, Mohr, Susanne, De Vera Mudry, Maria Cristina, Brown, Morris J., Ferber, Philippe
Publicado 2017

Novel Mechanism for Buffering Dietary Salt in Humans: Effects of Salt Loading on Skin Sodium, Vascular Endothelial Growth Factor C, and Blood Pressure

por Selvarajah, Viknesh, Mäki-Petäjä, Kaisa M., Pedro, Liliana, Bruggraber, Sylvaine F.A., Burling, Keith, Goodhart, Anna K., Brown, Morris J., McEniery, Carmel M., Wilkinson, Ian B.
Publicado 2017

Development of [(18)F]AldoView as the First Highly Selective Aldosterone Synthase PET Tracer for Imaging of Primary Hyperaldosteronism

por Sander, Kerstin, Gendron, Thibault, Cybulska, Klaudia A., Sirindil, Fatih, Zhou, Junhua, Kalber, Tammy L., Lythgoe, Mark F., Kurzawinski, Tom R., Brown, Morris J., Williams, Bryan, Årstad, Erik
Publicado 2021

Prevention And Treatment of Hypertension With Algorithm-based therapy (PATHWAY) number 2: protocol for a randomised crossover trial to determine optimal treatment for drug-resistan...

por Williams, Bryan, MacDonald, Thomas M, Caulfield, Mark, Cruickshank, J Kennedy, McInnes, Gordon, Sever, Peter, Webb, David J, Salsbury, Jackie, Morant, Steve, Ford, Ian, Brown, Morris J
Publicado 2015

Comparison of single and combination diuretics on glucose tolerance (PATHWAY-3): protocol for a randomised double-blind trial in patients with essential hypertension

por Brown, Morris J, Williams, Bryan, MacDonald, Thomas M, Caulfield, Mark, Cruickshank, J Kennedy, McInnes, Gordon, Sever, Peter, Webb, David J, Salsbury, Jackie, Morant, Steve, Ford, Ian
Publicado 2015

Monotherapy versus dual therapy for the initial treatment of hypertension (PATHWAY-1): a randomised double-blind controlled trial

por MacDonald, Thomas M, Williams, Bryan, Caulfield, Mark, Cruickshank, J Kennedy, McInnes, Gordon, Sever, Peter, Webb, David J, Mackenzie, Isla S, Salsbury, Jackie, Morant, Steve, Ford, Ian, Brown, Morris J
Publicado 2015

DACH1, a Zona Glomerulosa Selective Gene in the Human Adrenal, Activates Transforming Growth Factor-β Signaling and Suppresses Aldosterone Secretion

por Zhou, Junhua, Shaikh, Lalarukh Haris, Neogi, Sudeshna G., McFarlane, Ian, Zhao, Wanfeng, Figg, Nichola, Brighton, Cheryl A., Maniero, Carmela, Teo, Ada E.D., Azizan, Elena A. B., Brown, Morris J.
Publicado 2015

Regulation of aldosterone secretion by Ca(v)1.3

por Xie, Catherine B., Haris Shaikh, Lalarukh, Garg, Sumedha, Tanriver, Gizem, Teo, Ada E. D., Zhou, Junhua, Maniero, Carmela, Zhao, Wanfeng, Kang, Soosung, Silverman, Richard B., Azizan, Elena A. B., Brown, Morris J.
Publicado 2016

Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial

por Williams, Bryan, MacDonald, Thomas M, Morant, Steve, Webb, David J, Sever, Peter, McInnes, Gordon, Ford, Ian, Cruickshank, J Kennedy, Caulfield, Mark J, Salsbury, Jackie, Mackenzie, Isla, Padmanabhan, Sandosh, Brown, Morris J
Publicado 2015

Effect of amiloride, or amiloride plus hydrochlorothiazide, versus hydrochlorothiazide on glucose tolerance and blood pressure (PATHWAY-3): a parallel-group, double-blind randomise...

por Brown, Morris J, Williams, Bryan, Morant, Steve V, Webb, David J, Caulfield, Mark J, Cruickshank, J Kennedy, Ford, Ian, McInnes, Gordon, Sever, Peter, Salsbury, Jackie, Mackenzie, Isla S, Padmanabhan, Sandosh, MacDonald, Thomas M
Publicado 2016

Endocrine and haemodynamic changes in resistant hypertension, and blood pressure responses to spironolactone or amiloride: the PATHWAY-2 mechanisms substudies

por Williams, Bryan, MacDonald, Thomas M, Morant, Steve V, Webb, David J, Sever, Peter, McInnes, Gordon T, Ford, Ian, Cruickshank, J Kennedy, Caulfield, Mark J, Padmanabhan, Sandosh, Mackenzie, Isla S, Salsbury, Jackie, Brown, Morris J
Publicado 2018

Combination Therapy Is Superior to Sequential Monotherapy for the Initial Treatment of Hypertension: A Double‐Blind Randomized Controlled Trial

por MacDonald, Thomas M., Williams, Bryan, Webb, David J., Morant, Steve, Caulfield, Mark, Cruickshank, J. Kennedy, Ford, Ian, Sever, Peter, Mackenzie, Isla S., Padmanabhan, Sandosh, McCann, Gerald P., Salsbury, Jackie, McInnes, Gordon, Brown, Morris J.
Publicado 2017