Advances in mouse genetics for the study of human disease

por Brown, Steve D M
Publicado 2021

Towards an encyclopaedia of mammalian gene function: the International Mouse Phenotyping Consortium

por Brown, Steve D. M., Moore, Mark W.
Publicado 2012

The dark genome and pleiotropy: challenges for precision medicine

por Brown, Steve D. M., Lad, Heena V.
Publicado 2019

Understanding Mammalian Genetic Systems: The Challenge of Phenotyping in the Mouse

por Brown, Steve D. M, Hancock, John M, Gates, Hilary
Publicado 2006

Cellular content plays a crucial role in Non‐typeable Haemophilus influenzae infection of preinflamed Junbo mouse middle ear

por Vikhe, Pratik P., Purnell, Tom, Brown, Steve D.M., Hood, Derek W.
Publicado 2018

Cellular Immune Response against Nontypeable Haemophilus influenzae Infecting the Preinflamed Middle Ear of the Junbo Mouse

por Vikhe, Pratik P., Purnell, Tom, Brown, Steve D. M., Hood, Derek W.
Publicado 2019

The Jeff Mouse Mutant Model for Chronic Otitis Media Manifests Gain-of-Function as Well as Loss-of-Function Effects

por Kubinyecz, Oana, Vikhe, Pratik P., Purnell, Thomas, Brown, Steve D. M., Tateossian, Hilda
Publicado 2020

Melody, an ENU mutation in Caspase 3, alters the catalytic cysteine residue and causes sensorineural hearing loss in mice

por Parker, Andrew, Hardisty-Hughes, Rachel E., Wisby, Laura, Joyce, Susan, Brown, Steve D. M.
Publicado 2010

Surveying the Down syndrome mouse model resource identifies critical regions responsible for chronic otitis media

por Bhutta, Mahmood F., Cheeseman, Michael T., Herault, Yann, Yu, Yuejin E., Brown, Steve D. M.
Publicado 2013

Interactions between the otitis media gene, Fbxo11, and p53 in the mouse embryonic lung

por Tateossian, Hilda, Morse, Susan, Simon, Michelle M., Dean, Charlotte H., Brown, Steve D. M.
Publicado 2015

Mutation in Fbxo11 Leads to Altered Immune Cell Content in Jeff Mouse Model of Otitis Media

por Vikhe, Pratik P., Tateossian, Hilda, Bharj, Gurpreet, Brown, Steve D.M., Hood, Derek W.
Publicado 2020

Multivariate phenotype analysis enables genome-wide inference of mammalian gene function

por Nicholson, George, Morgan, Hugh, Ganjgahi, Habib, Brown, Steve D. M., Mallon, Ann-Marie, Holmes, Chris
Publicado 2022

Gelsolin Plays a Role in the Actin Polymerization Complex of Hair Cell Stereocilia

por Mburu, Philomena, Romero, María Rosario, Hilton, Helen, Parker, Andrew, Townsend, Stuart, Kikkawa, Yoshiaki, Brown, Steve D. M.
Publicado 2010

The Actin-Binding Proteins Eps8 and Gelsolin Have Complementary Roles in Regulating the Growth and Stability of Mechanosensory Hair Bundles of Mammalian Cochlear Outer Hair Cells

por Olt, Jennifer, Mburu, Philomena, Johnson, Stuart L., Parker, Andy, Kuhn, Stephanie, Bowl, Mike, Marcotti, Walter, Brown, Steve D. M.
Publicado 2014

Loss of the homeostatic protein BPIFA1, leads to exacerbation of otitis media severity in the Junbo mouse model

por Mulay, Apoorva, Hood, Derek W., Williams, Debbie, Russell, Catherine, Brown, Steve D. M., Bingle, Lynne, Cheeseman, Michael, Bingle, Colin D.
Publicado 2018

Otitis media in the Tgif knockout mouse implicates TGFβ signalling in chronic middle ear inflammatory disease

por Tateossian, Hilda, Morse, Susan, Parker, Andrew, Mburu, Philomena, Warr, Nick, Acevedo-Arozena, Abraham, Cheeseman, Michael, Wells, Sara, Brown, Steve D.M.
Publicado 2013

Regulatory Variation at Glypican-3 Underlies a Major Growth QTL in Mice

por Oliver, Fiona, Christians, Julian K, Liu, Xiaojun, Rhind, Susan, Verma, Vinesh, Davison, Claire, Brown, Steve D. M, Denny, Paul, Keightley, Peter D
Publicado 2005

The Opdc missense mutation of Pax2 has a milder than loss-of-function phenotype

por Cross, Sally H., McKie, Lisa, West, Katrine, Coghill, Emma L., Favor, Jack, Bhattacharya, Shoumo, Brown, Steve D.M., Jackson, Ian J.
Publicado 2011

α-Synuclein levels modulate Huntington's disease in mice

por Corrochano, Silvia, Renna, Maurizio, Carter, Sarah, Chrobot, Nichola, Kent, Rose, Stewart, Michelle, Cooper, Jason, Brown, Steve D.M., Rubinsztein, David C., Acevedo-Arozena, Abraham
Publicado 2012

The goya mouse mutant reveals distinct newly identified roles for MAP3K1 in the development and survival of cochlear sensory hair cells

por Parker, Andrew, Cross, Sally H., Jackson, Ian J., Hardisty-Hughes, Rachel, Morse, Susan, Nicholson, George, Coghill, Emma, Bowl, Michael R., Brown, Steve D. M.
Publicado 2015