Integrin-mediated resistance to epidermal growth factor receptor-targeted therapy: an inflammatory situation

por Brown, Wells S, Wendt, Michael K
Publicado 2014

FGFR signaling maintains a drug persistent cell population following epithelial-mesenchymal transition

por Brown, Wells S., Akhand, Saeed Salehin, Wendt, Michael K.
Publicado 2016

Clustering T cell GM1 Lipid Rafts Increases Cellular Resistance to Shear on Fibronectin through Changes in Integrin Affinity and Cytoskeletal Dynamics

por Mitchell, Jason S., Brown, Wells S., Woodside, Darren G., Vanderslice, Peter, McIntyre, Bradley W.
Publicado 2009

Biased signaling downstream of epidermal growth factor receptor regulates proliferative versus apoptotic response to ligand

por Ali, Remah, Brown, Wells, Purdy, Stephen Connor, Davisson, V. Jo, Wendt, Michael K.
Publicado 2018

A Carbonic Anhydrase IX/SLC1A5 Axis Regulates Glutamine Metabolism Dependent Ferroptosis in Hypoxic Tumor Cells

por Venkateswaran, Geetha, McDonald, Paul C., Chafe, Shawn C., Brown, Wells S., Gerbec, Zachary J., Awrey, Shannon J., Parker, Seth J., Dedhar, Shoukat
Publicado 2023

Overcoming Adaptive Resistance to KRAS and MEK Inhibitors by Co-targeting mTORC1/2 Complexes in Pancreatic Cancer

por Brown, Wells S., McDonald, Paul C., Nemirovsky, Oksana, Awrey, Shannon, Chafe, Shawn C., Schaeffer, David F., Li, Jinyang, Renouf, Daniel J., Stanger, Ben Z., Dedhar, Shoukat
Publicado 2020

Correction: Epigenetic targeting of neuropilin-1 prevents bypass signaling in drug-resistant breast cancer

por Abdullah, Ammara, Akhand, Saeed Salehin, Paez, Juan Sebastian Paez, Brown, Wells, Pan, Li, Libring, Sarah, Badamy, Michael, Dykuizen, Emily, Solorio, Luis, Andy Tao, W., Wendt, Michael K.
Publicado 2023

Epigenetic targeting of neuropilin-1 prevents bypass signaling in drug-resistant breast cancer

por Abdullah, Ammara, Akhand, Saeed Salehin, Paez, Juan Sebastian Paez, Brown, Wells, Pan, Li, Libring, Sarah, Badamy, Michael, Dykuizen, Emily, Solorio, Luis, Andy Tao, W., Wendt, Michael K.
Publicado 2020

Syntaxin4-Munc18c Interaction Promotes Breast Tumor Invasion and Metastasis by Regulating MT1-MMP Trafficking

por Brasher, Megan I., Chafe, Shawn C., McDonald, Paul C., Nemirovsky, Oksana, Gorshtein, Genya, Gerbec, Zachary J., Brown, Wells S., Grafinger, Olivia R., Marchment, Matthew, Matus, Esther, Dedhar, Shoukat, Coppolino, Marc G.
Publicado 2022

The PI3-Kinase Delta Inhibitor Idelalisib (GS-1101) Targets Integrin-Mediated Adhesion of Chronic Lymphocytic Leukemia (CLL) Cell to Endothelial and Marrow Stromal Cells

por Fiorcari, Stefania, Brown, Wells S., McIntyre, Bradley W., Estrov, Zeev, Maffei, Rossana, O’Brien, Susan, Sivina, Mariela, Hoellenriegel, Julia, Wierda, William G., Keating, Michael J., Ding, Wei, Kay, Neil E., Lannutti, Brian J., Marasca, Roberto, Burger, Jan A.
Publicado 2013

Genome-wide synthetic lethal screen unveils novel CAIX-NFS1/xCT axis as a targetable vulnerability in hypoxic solid tumors

por Chafe, Shawn C., Vizeacoumar, Frederick S., Venkateswaran, Geetha, Nemirovsky, Oksana, Awrey, Shannon, Brown, Wells S., McDonald, Paul C., Carta, Fabrizio, Metcalfe, Andrew, Karasinska, Joanna M., Huang, Ling, Muthuswamy, Senthil K., Schaeffer, David F., Renouf, Daniel J., Supuran, Claudiu T., Vizeacoumar, Franco J., Dedhar, Shoukat
Publicado 2021