Multifunctional roles of the autoimmune disease-associated tyrosine phosphatase PTPN22 in regulating T cell homeostasis

por Salmond, Robert J, Brownlie, Rebecca J, Zamoyska, Rose
Publicado 2015

Mechanistic Target of Rapamycin Complex 1/S6 Kinase 1 Signals Influence T Cell Activation Independently of Ribosomal Protein S6 Phosphorylation

por Salmond, Robert J., Brownlie, Rebecca J., Meyuhas, Oded, Zamoyska, Rose
Publicado 2015

Deletion of PTPN22 improves effector and memory CD8(+) T cell responses to tumors

por Brownlie, Rebecca J., Wright, David, Zamoyska, Rose, Salmond, Robert J.
Publicado 2019

The tyrosine phosphatase Ptpn22 discriminates weak, self-peptide from strong agonist T cell receptor signals

por Salmond, Robert J., Brownlie, Rebecca J., Morrison, Vicky L., Zamoyska, Rose
Publicado 2014

Resistance to TGFβ suppression and improved anti-tumor responses in CD8(+) T cells lacking PTPN22

por Brownlie, Rebecca J., Garcia, Celine, Ravasz, Mate, Zehn, Dietmar, Salmond, Robert J., Zamoyska, Rose
Publicado 2017

Loss of the Protein Tyrosine Phosphatase PTPN22 Reduces Mannan-Induced Autoimmune Arthritis in SKG Mice

por Sood, Shatakshi, Brownlie, Rebecca J., Garcia, Celine, Cowan, Graeme, Salmond, Robert J., Sakaguchi, Shimon, Zamoyska, Rose
Publicado 2016

Coordination of asparagine uptake and asparagine synthetase expression modulates CD8(+) T cell activation

por Hope, Helen Carrasco, Brownlie, Rebecca J., Fife, Christopher M., Steele, Lynette, Lorger, Mihaela, Salmond, Robert J.
Publicado 2021

Hematopoietic stem cell gene therapy targeting TGFβ enhances the efficacy of irradiation therapy in a preclinical glioblastoma model

por Andreou, Tereza, Williams, Jennifer, Brownlie, Rebecca J, Salmond, Robert J, Watson, Erica, Shaw, Gary, Melcher, Alan, Wurdak, Heiko, Short, Susan C, Lorger, Mihaela
Publicado 2021

Distinct cell-specific control of autoimmunity and infection by FcγRIIb

por Brownlie, Rebecca J., Lawlor, Kate E., Niederer, Heather A., Cutler, Antony J., Xiang, Zou, Clatworthy, Menna R., Floto, R. Andres, Greaves, David R., Lyons, Paul A., Smith, Kenneth G.C.
Publicado 2008

Hematopoietic Stem Cell Gene Therapy for Brain Metastases Using Myeloid Cell–Specific Gene Promoters

por Andreou, Tereza, Rippaus, Nora, Wronski, Krzysztof, Williams, Jennifer, Taggart, David, Cherqui, Stephanie, Sunderland, Ashley, Kartika, Yolanda D, Egnuni, Teklu, Brownlie, Rebecca J, Mathew, Ryan K, Holmen, Sheri L, Fife, Christopher, Droop, Alastair, Lorger, Mihaela
Publicado 2019

miR-181a/b-1 controls thymic selection of Treg cells and tunes their suppressive capacity

por Łyszkiewicz, Marcin, Winter, Samantha J., Witzlau, Katrin, Föhse, Lisa, Brownlie, Rebecca, Puchałka, Jacek, Verheyden, Nikita A., Kunze-Schumacher, Heike, Imelmann, Esther, Blume, Jonas, Raha, Solaiman, Sekiya, Takashi, Yoshimura, Akihiko, Frueh, Jochen T., Ullrich, Evelyn, Huehn, Jochen, Weiss, Siegfried, Gutierrez, Maximiliano G., Prinz, Immo, Zamoyska, Rose, Ziętara, Natalia, Krueger, Andreas
Publicado 2019

Cytokine receptor IL27RA is an NF-κB–responsive gene involved in CD38 upregulation in multiple myeloma

por Brownlie, Rebecca J., Kennedy, Ruth, Wilson, Erica B., Milanovic, Maja, Taylor, Claire F., Wang, Dapeng, Davies, John R., Owston, Heather, Adams, Emma J., Stephenson, Sophie, Caeser, Rebecca, Gewurz, Benjamin E., Giannoudis, Peter V., Scuoppo, Claudio, McGonagle, Dennis, Hodson, Daniel J., Tooze, Reuben M., Doody, Gina M., Cook, Gordon, Westhead, David R., Klein, Ulf
Publicado 2023