Enhanced annotation of CD45RA to distinguish T cell subsets in single-cell RNA-seq via machine learning

por Ran, Ran, Brubaker, Douglas K
Publicado 2023

A dynamical systems model of progesterone receptor interactions with inflammation in human parturition

por Brubaker, Douglas, Barbaro, Alethea, R. Chance, Mark, Mesiano, Sam
Publicado 2016

Computational translation of genomic responses from experimental model systems to humans

por Brubaker, Douglas K., Proctor, Elizabeth A., Haigis, Kevin M., Lauffenburger, Douglas A.
Publicado 2019

Differential responses of primary neuron-secreted MCP-1 and IL-9 to type 2 diabetes and Alzheimer’s disease-associated metabolites

por Ball, Brendan K., Kuhn, Madison K., Fleeman, Rebecca M., Proctor, Elizabeth A., Brubaker, Douglas K.
Publicado 2023

Computational Interspecies Translation Between Alzheimer’s Disease Mouse Models and Human Subjects Identifies Innate Immune Complement, TYROBP, and TAM Receptor Agonist Signatures,...

por Lee, Meelim J., Wang, Chuangqi, Carroll, Molly J., Brubaker, Douglas K., Hyman, Bradley T., Lauffenburger, Douglas A.
Publicado 2021

Endogenous production of hyaluronan, PRG4, and cytokines is sensitive to cyclic loading in synoviocytes

por Pendyala, Meghana, Woods, Paige S., Brubaker, Douglas K., Blaber, Elizabeth A., Schmidt, Tannin A., Chan, Deva D.
Publicado 2022

Cell surface integrin α5ß1 clustering negatively regulates receptor tyrosine kinase signaling in colorectal cancer cells via glycogen synthase kinase 3

por Starchenko, Alina, Graves-Deal, Ramona, Brubaker, Douglas, Li, Cunxi, Yang, Yuping, Singh, Bhuminder, Coffey, Robert J, Lauffenburger, Douglas A
Publicado 2021

Cross-species transcriptomic signatures predict response to MK2 inhibition in mouse models of chronic inflammation

por Suarez-Lopez, Lucia, Shui, Bing, Brubaker, Douglas K., Hill, Marza, Bergendorf, Alexander, Changelian, Paul S., Laguna, Aisha, Starchenko, Alina, Lauffenburger, Douglas A., Haigis, Kevin M.
Publicado 2021

Coagulopathy signature precedes and predicts severity of end‐organ heat stroke pathology in a mouse model

por Proctor, Elizabeth A., Dineen, Shauna M., Van Nostrand, Stephen C., Kuhn, Madison K., Barrett, Christopher D., Brubaker, Douglas K., Yaffe, Michael B., Lauffenburger, Douglas A., Leon, Lisa R.
Publicado 2020

Vaginal epithelial dysfunction is mediated by the microbiome, metabolome, and mTOR signaling

por Berard, Alicia R., Brubaker, Douglas K., Birse, Kenzie, Lamont, Alana, Mackelprang, Romel D., Noël-Romas, Laura, Perner, Michelle, Hou, Xuanlin, Irungu, Elizabeth, Mugo, Nelly, Knodel, Samantha, Muwonge, Timothy R., Katabira, Elly, Hughes, Sean M., Levy, Claire, Calienes, Fernanda L., Lauffenburger, Douglas A., Baeten, Jared M., Celum, Connie, Hladik, Florian, Lingappa, Jairam, Burgener, Adam D.
Publicado 2023