In silico prediction and in vivo testing of promoters targeting GABAergic inhibitory neurons

por Niibori, Yosuke, Duba-Kiss, Robert, Bruder, Joseph T., Smith, Jared B., Hampson, David R.
Publicado 2023

Liver-Targeted AAV8 Gene Therapy Ameliorates Skeletal and Cardiovascular Pathology in a Mucopolysaccharidosis IVA Murine Model

por Sawamoto, Kazuki, Karumuthil-Melethil, Subha, Khan, Shaukat, Stapleton, Molly, Bruder, Joseph T., Danos, Olivier, Tomatsu, Shunji
Publicado 2020

Gene therapy using an ortholog of human fragile X mental retardation protein partially rescues behavioral abnormalities and EEG activity

por Hooper, Alexander W.M., Wong, Hayes, Niibori, Yosuke, Abdoli, Rozita, Karumuthil-Melethil, Subha, Qiao, Chunping, Danos, Olivier, Bruder, Joseph T., Hampson, David R.
Publicado 2021

Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors

por Hollidge, Bradley S., Carroll, Hayley B., Qian, Randolph, Fuller, Madison L., Giles, April R., Mercer, Andrew C., Danos, Olivier, Liu, Ye, Bruder, Joseph T., Smith, Jared B.
Publicado 2022

Sex Difference Leads to Differential Gene Expression Patterns and Therapeutic Efficacy in Mucopolysaccharidosis IVA Murine Model Receiving AAV8 Gene Therapy

por Piechnik, Matthew, Amendum, Paige C., Sawamoto, Kazuki, Stapleton, Molly, Khan, Shaukat, Fnu, Nidhi, Álvarez, Victor, Pachon, Angelica Maria Herreño, Danos, Olivier, Bruder, Joseph T., Karumuthil-Melethil, Subha, Tomatsu, Shunji
Publicado 2022

Modification of Ad5 Hexon Hypervariable Regions Circumvents Pre-Existing Ad5 Neutralizing Antibodies and Induces Protective Immune Responses

por Bruder, Joseph T., Semenova, Elena, Chen, Ping, Limbach, Keith, Patterson, Noelle B., Stefaniak, Maureen E., Konovalova, Svetlana, Thomas, Charlie, Hamilton, Melissa, King, C. Richter, Richie, Thomas L., Doolan, Denise L.
Publicado 2012

Correction: Modification of Ad5 Hexon Hypervariable Regions Circumvents Pre-Existing Ad5 Neutralizing Antibodies and Induces Protective Immune Responses

por Bruder, Joseph T., Semenova, Elena, Chen, Ping, Limbach, Keith, Patterson, Noelle B., Stefaniak, Maureen E., Konovalova, Svetlana, Thomas, Charlie, Hamilton, Melissa, King, C. Richter, Richie, Thomas L., Doolan, Denise L.
Publicado 2012

Profiling the Targets of Protective CD8(+) T Cell Responses to Infection

por Bruder, Joseph T., Chen, Ping, Ekberg, Greg, Smith, Emily C., Lazarski, Christopher A., Myers, Bennett A., Bolton, Jessica, Sedegah, Martha, Villasante, Eileen, Richie, Thomas L., King, C. Richter, Aguiar, Joao C., Doolan, Denise L., Brough, Douglas E.
Publicado 2017

Viral vectors for malaria vaccine development

por Li, Shengqiang, Locke, Emily, Bruder, Joseph, Clarke, David, Doolan, Denise L., Havenga, Menzo J.E., Hill, Adrian V.S., Liljestrom, Peter, Monath, Thomas P., Naim, Hussein Y., Ockenhouse, Christian, Tang, De-chu C., Van Kampen, Kent R., Viret, Jean-Francois, Zavala, Fidel, Dubovsky, Filip
Publicado 2007

A Glycolipid Adjuvant, 7DW8-5, Enhances CD8+ T Cell Responses Induced by an Adenovirus-Vectored Malaria Vaccine in Non-Human Primates

por Padte, Neal N., Boente-Carrera, Mar, Andrews, Chasity D., McManus, Jenny, Grasperge, Brooke F., Gettie, Agegnehu, Coelho-dos-Reis, Jordana G., Li, Xiangming, Wu, Douglass, Bruder, Joseph T., Sedegah, Martha, Patterson, Noelle, Richie, Thomas L., Wong, Chi-Huey, Ho, David D., Vasan, Sandhya, Tsuji, Moriya
Publicado 2013

Sterile Protection against Plasmodium knowlesi in Rhesus Monkeys from a Malaria Vaccine: Comparison of Heterologous Prime Boost Strategies

por Jiang, George, Shi, Meng, Conteh, Solomon, Richie, Nancy, Banania, Glenna, Geneshan, Harini, Valencia, Anais, Singh, Priti, Aguiar, Joao, Limbach, Keith, Kamrud, Kurt I., Rayner, Jonathan, Smith, Jonathan, Bruder, Joseph T., King, C. Richter, Tsuboi, Takafumi, Takeo, Satoru, Endo, Yaeta, Doolan, Denise L., Richie, Thomas L., Weiss, Walter R.
Publicado 2009

New gorilla adenovirus vaccine vectors induce potent immune responses and protection in a mouse malaria model

por Limbach, Keith, Stefaniak, Maureen, Chen, Ping, Patterson, Noelle B., Liao, Grant, Weng, Shaojie, Krepkiy, Svetlana, Ekberg, Greg, Torano, Holly, Ettyreddy, Damodar, Gowda, Kalpana, Sonawane, Sharvari, Belmonte, Arnel, Abot, Esteban, Sedegah, Martha, Hollingdale, Michael R., Moormann, Ann, Vulule, John, Villasante, Eileen, Richie, Thomas L., Brough, Douglas E., Bruder, Joseph T.
Publicado 2017

Identification and localization of minimal MHC-restricted CD8+ T cell epitopes within the Plasmodium falciparum AMA1 protein

por Sedegah, Martha, Kim, Yohan, Peters, Bjoern, McGrath, Shannon, Ganeshan, Harini, Lejano, Jennylynn, Abot, Esteban, Banania, Glenna, Belmonte, Maria, Sayo, Renato, Farooq, Fouzia, Doolan, Denise L, Regis, David, Tamminga, Cindy, Chuang, Ilin, Bruder, Joseph T, King, C Richter, Ockenhouse, Christian F, Faber, Bart, Remarque, Edmond, Hollingdale, Michael R, Richie, Thomas L, Sette, Alessandro
Publicado 2010

Characterization and biodistribution of under-employed gene therapy vector AAV7

por Yost, Samantha A., Firlar, Emre, Glenn, Justin D., Carroll, Hayley B., Foltz, Steven, Giles, April R., Egley, Jenny M., Firnberg, Elad, Cho, Sungyeon, Nguyen, Trang, Henry, William M., Janczura, Karolina J., Bruder, Joseph, Liu, Ye, Danos, Olivier, Karumuthil-Melethil, Subha, Pannem, Sanjana, Yost, Valerie, Engelson, Yelena, Kaelber, Jason T., Dimant, Hemi, Smith, Jared B., Mercer, Andrew C.
Publicado 2023

Human adenovirus 5-vectored Plasmodium falciparum NMRC-M3V-Ad-PfCA vaccine encoding CSP and AMA1 is safe, well-tolerated and immunogenic but does not protect against controlled hum...

por Tamminga, Cindy, Sedegah, Martha, Maiolatesi, Santina, Fedders, Charlotte, Reyes, Sharina, Reyes, Anatalio, Vasquez, Carlos, Alcorta, Yolanda, Chuang, Ilin, Spring, Michele, Kavanaugh, Michael, Ganeshan, Harini, Huang, Jun, Belmonte, Maria, Abot, Esteban, Belmonte, Arnel, Banania, JoGlenna, Farooq, Fouzia, Murphy, Jittawadee, Komisar, Jack, Richie, Nancy O, Bennett, Jason, Limbach, Keith, Patterson, Noelle B, Bruder, Joseph T, Shi, Meng, Miller, Edward, Dutta, Sheetij, Diggs, Carter, Soisson, Lorraine A, Hollingdale, Michael R, Epstein, Judith E, Richie, Thomas L
Publicado 2013

Adenovirus 5-Vectored P. falciparum Vaccine Expressing CSP and AMA1. Part A: Safety and Immunogenicity in Seronegative Adults

por Sedegah, Martha, Tamminga, Cindy, McGrath, Shannon, House, Brent, Ganeshan, Harini, Lejano, Jennylynn, Abot, Esteban, Banania, Glenna J., Sayo, Renato, Farooq, Fouzia, Belmonte, Maria, Manohar, Nalini, Richie, Nancy O., Wood, Chloe, Long, Carole A., Regis, David, Williams, Francis T., Shi, Meng, Chuang, Ilin, Spring, Michele, Epstein, Judith E., Mendoza-Silveiras, Jose, Limbach, Keith, Patterson, Noelle B., Bruder, Joseph T., Doolan, Denise L., King, C. Richter, Soisson, Lorraine, Diggs, Carter, Carucci, Daniel, Dutta, Sheetij, Hollingdale, Michael R., Ockenhouse, Christian F., Richie, Thomas L.
Publicado 2011

Adenovirus-5-Vectored P. falciparum Vaccine Expressing CSP and AMA1. Part B: Safety, Immunogenicity and Protective Efficacy of the CSP Component

por Tamminga, Cindy, Sedegah, Martha, Regis, David, Chuang, Ilin, Epstein, Judith E., Spring, Michele, Mendoza-Silveiras, Jose, McGrath, Shannon, Maiolatesi, Santina, Reyes, Sharina, Steinbeiss, Victoria, Fedders, Charlotte, Smith, Kathryn, House, Brent, Ganeshan, Harini, Lejano, Jennylynn, Abot, Esteban, Banania, Glenna J., Sayo, Renato, Farooq, Fouzia, Belmonte, Maria, Murphy, Jittawadee, Komisar, Jack, Williams, Jackie, Shi, Meng, Brambilla, Donald, Manohar, Nalini, Richie, Nancy O., Wood, Chloe, Limbach, Keith, Patterson, Noelle B., Bruder, Joseph T., Doolan, Denise L., King, C. Richter, Diggs, Carter, Soisson, Lorraine, Carucci, Daniel, Levine, Gail, Dutta, Sheetij, Hollingdale, Michael R., Ockenhouse, Christian F., Richie, Thomas L.
Publicado 2011

DNA Prime/Adenovirus Boost Malaria Vaccine Encoding P. falciparum CSP and AMA1 Induces Sterile Protection Associated with Cell-Mediated Immunity

por Chuang, Ilin, Sedegah, Martha, Cicatelli, Susan, Spring, Michele, Polhemus, Mark, Tamminga, Cindy, Patterson, Noelle, Guerrero, Melanie, Bennett, Jason W., McGrath, Shannon, Ganeshan, Harini, Belmonte, Maria, Farooq, Fouzia, Abot, Esteban, Banania, Jo Glenna, Huang, Jun, Newcomer, Rhonda, Rein, Lisa, Litilit, Dianne, Richie, Nancy O., Wood, Chloe, Murphy, Jittawadee, Sauerwein, Robert, Hermsen, Cornelus C., McCoy, Andrea J., Kamau, Edwin, Cummings, James, Komisar, Jack, Sutamihardja, Awalludin, Shi, Meng, Epstein, Judith E., Maiolatesi, Santina, Tosh, Donna, Limbach, Keith, Angov, Evelina, Bergmann-Leitner, Elke, Bruder, Joseph T., Doolan, Denise L., King, C. Richter, Carucci, Daniel, Dutta, Sheetij, Soisson, Lorraine, Diggs, Carter, Hollingdale, Michael R., Ockenhouse, Christian F., Richie, Thomas L.
Publicado 2013