High Levels of Canonical Wnt Signaling Lead to Loss of Stemness and Increased Differentiation in Hematopoietic Stem Cells

por Famili, Farbod, Brugman, Martijn H., Taskesen, Erdogan, Naber, Brigitta E.A., Fodde, Riccardo, Staal, Frank J.T.
Publicado 2016

Inhibition of Thrombopoietin/Mpl Signaling in Adult Hematopoiesis Identifies New Candidates for Hematopoietic Stem Cell Maintenance

por Kohlscheen, Saskia, Wintterle, Sabine, Schwarzer, Adrian, Kamp, Christel, Brugman, Martijn H., Breuer, Daniel C., Büsche, Guntram, Baum, Christopher, Modlich, Ute
Publicado 2015

Identification of a small molecule for enhancing lentiviral transduction of T cells

por Malach, Paulina, Kay, Charlotte, Tinworth, Chris, Patel, Florence, Joosse, Bryan, Wade, Jennifer, Rosa do Carmo, Marlene, Donovan, Brian, Brugman, Martijn, Montiel-Equihua, Claudia, Francis, Natalie
Publicado 2023

Sustained Engraftment of Cryopreserved Human Bone Marrow CD34(+) Cells in Young Adult NSG Mice

por Wiekmeijer, Anna-Sophia, Pike-Overzet, Karin, Brugman, Martijn H., Salvatori, Daniela C.F., Egeler, R. Maarten, Bredius, Robbert G.M., Fibbe, Willem E., Staal, Frank J.T.
Publicado 2014

Avoiding cytotoxicity of transposases by dose-controlled mRNA delivery

por Galla, Melanie, Schambach, Axel, Falk, Christine S., Maetzig, Tobias, Kuehle, Johannes, Lange, Kathrin, Zychlinski, Daniela, Heinz, Niels, Brugman, Martijn H., Göhring, Gudrun, Izsvák, Zsuzsanna, Ivics, Zoltán, Baum, Christopher
Publicado 2011

Avoiding cytotoxicity of transposases by dose-controlled mRNA delivery

por Galla, Melanie, Schambach, Axel, Falk, Christine S., Maetzig, Tobias, Kuehle, Johannes, Lange, Kathrin, Zychlinski, Daniela, Heinz, Niels, Brugman, Martijn H., Göhring, Gudrun, Izsvák, Zsuzsanna, Ivics, Zoltán, Baum, Christopher
Publicado 2012

Functional definition of a transcription factor hierarchy regulating T cell lineage commitment

por Garcia-Perez, Laura, Famili, Farbod, Cordes, Martijn, Brugman, Martijn, van Eggermond, Marja, Wu, Haoyu, Chouaref, Jihed, Granado, David San León, Tiemessen, Machteld M., Pike-Overzet, Karin, Daxinger, Lucia, Staal, Frank J. T.
Publicado 2020

Eliminating HIV-1 Packaging Sequences from Lentiviral Vector Proviruses Enhances Safety and Expedites Gene Transfer for Gene Therapy

por Vink, Conrad A., Counsell, John R., Perocheau, Dany P., Karda, Rajvinder, Buckley, Suzanne M.K., Brugman, Martijn H., Galla, Melanie, Schambach, Axel, McKay, Tristan R., Waddington, Simon N., Howe, Steven J.
Publicado 2017

The Nuclear Effector of Wnt-Signaling, Tcf1, Functions as a T-Cell–Specific Tumor Suppressor for Development of Lymphomas

por Tiemessen, Machteld M., Baert, Miranda R. M., Schonewille, Tom, Brugman, Martijn H., Famili, Farbod, Salvatori, Daniela C. F., Meijerink, Jules P. P., Ozbek, Ugur, Clevers, Hans, van Dongen, Jacques J. M., Staal, Frank J. T.
Publicado 2012

Dynamic clonal hematopoiesis and functional T-cell immunity in a supercentenarian

por van den Akker, Erik B., Makrodimitris, Stavros, Hulsman, Marc, Brugman, Martijn H., Nikolic, Tatjana, Bradley, Ted, Waisfisz, Quinten, Baas, Frank, Jakobs, Marja E., de Jong, Daphne, Slagboom, P. Eline, Staal, Frank J. T., Reinders, Marcel J. T., Holstege, Henne
Publicado 2020

Somatic mutations found in the healthy blood compartment of a 115-yr-old woman demonstrate oligoclonal hematopoiesis

por Holstege, Henne, Pfeiffer, Wayne, Sie, Daoud, Hulsman, Marc, Nicholas, Thomas J., Lee, Clarence C., Ross, Tristen, Lin, Jue, Miller, Mark A., Ylstra, Bauke, Meijers-Heijboer, Hanne, Brugman, Martijn H., Staal, Frank J.T., Holstege, Gert, Reinders, Marcel J.T., Harkins, Timothy T., Levy, Samuel, Sistermans, Erik A.
Publicado 2014

Rapid Lentiviral Vector Producer Cell Line Generation Using a Single DNA Construct

por Chen, Yu Hua, Pallant, Celeste, Sampson, Christopher J., Boiti, Alessia, Johnson, Sabine, Brazauskas, Pijus, Hardwicke, Philip, Marongiu, Michela, Marinova, Vanesa M., Carmo, Marlene, Sweeney, Nathan P., Richard, Ashkenaz, Shillings, Anthony, Archibald, Peter, Puschmann, Eva, Mouzon, Bernadette, Grose, David, Mendez-Tavio, Miriam, Chen, Mao Xiang, Warr, Stephen R.C., Senussi, Tarik, Carter, Paul S., Baker, Sean, Jung, Cindy, Brugman, Martijn H., Howe, Steven J., Vink, Conrad A.
Publicado 2020