From Powders to Single Crystals: A Crystallographer’s Toolbox for Small-Molecule Structure Determination

por Newman, Justin A., Iuzzolino, Luca, Tan, Melissa, Orth, Peter, Bruhn, Jessica, Lee, Alfred Y.
Publicado 2022

Absolute configuration determination of pharmaceutical crystalline powders by MicroED via chiral salt formation

por Wang, Bo, Bruhn, Jessica F., Weldeab, Asmerom, Wilson, Timothy S., McGilvray, Philip T., Mashore, Michael, Song, Qiong, Scapin, Giovanna, Lin, Yiqing
Publicado 2022

Cryo-EM structure of the HIV-1 Pol polyprotein provides insights into virion maturation

por Harrison, Jerry Joe E. K., Passos, Dario Oliveira, Bruhn, Jessica F., Bauman, Joseph D., Tuberty, Lynda, DeStefano, Jeffrey J., Ruiz, Francesc Xavier, Lyumkis, Dmitry, Arnold, Eddy
Publicado 2022

Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies

por Murin, Charles D., Gilchuk, Pavlo, Ilinykh, Philipp A., Huang, Kai, Kuzmina, Natalia, Shen, Xiaoli, Bruhn, Jessica F., Bryan, Aubrey L., Davidson, Edgar, Doranz, Benjamin J., Williamson, Lauren E., Copps, Jeffrey, Alkutkar, Tanwee, Flyak, Andrew I., Bukreyev, Alexander, Crowe, James E., Ward, Andrew B.
Publicado 2021

Small Molecule Microcrystal Electron Diffraction for the Pharmaceutical Industry–Lessons Learned From Examining Over Fifty Samples

por Bruhn, Jessica F., Scapin, Giovanna, Cheng, Anchi, Mercado, Brandon Q., Waterman, David G., Ganesh, Thejusvi, Dallakyan, Sargis, Read, Brandon N., Nieusma, Travis, Lucier, Kyle W., Mayer, Megan L., Chiang, Nicole J., Poweleit, Nicole, McGilvray, Philip T., Wilson, Timothy S., Mashore, Michael, Hennessy, Camille, Thomson, Sean, Wang, Bo, Potter, Clinton S., Carragher, Bridget
Publicado 2021