Human Pluripotent Stem Cells: A Unique Tool for Toxicity Testing in Pancreatic Progenitor and Endocrine Cells

por MacFarlane, Erin M., Bruin, Jennifer E.
Publicado 2021

Long-Term Consequences of Fetal and Neonatal Nicotine Exposure: A Critical Review

por Bruin, Jennifer E., Gerstein, Hertzel C., Holloway, Alison C.
Publicado 2010

Sex-specific Associations Between Type 2 Diabetes Incidence and Exposure to Dioxin and Dioxin-like Pollutants: A Meta-analysis

por Gang, Noa, Van Allen, Kyle, Villeneuve, Paul J., MacDonald, Heather, Bruin, Jennifer E.
Publicado 2022

Persistent organic pollutants and β-cell toxicity: a comprehensive review

por Hoyeck, Myriam P., Matteo, Geronimo, MacFarlane, Erin M., Perera, Ineli, Bruin, Jennifer E.
Publicado 2022

Accelerated Maturation of Human Stem Cell-Derived Pancreatic Progenitor Cells into Insulin-Secreting Cells in Immunodeficient Rats Relative to Mice

por Bruin, Jennifer E., Asadi, Ali, Fox, Jessica K., Erener, Suheda, Rezania, Alireza, Kieffer, Timothy J.
Publicado 2015

Prenatal exposure to perfluoroalkyl substances and inflammatory biomarker concentrations

por Palaniyandi, Jana, Bruin, Jennifer E., Kumarathasan, Premkumari, MacPherson, Susan, Borghese, Michael M., Ashley-Martin, Jillian
Publicado 2023

Fetal and Neonatal Nicotine Exposure in Wistar Rats Causes Progressive Pancreatic Mitochondrial Damage and Beta Cell Dysfunction

por Bruin, Jennifer E., Petre, Maria A., Raha, Sandeep, Morrison, Katherine M., Gerstein, Hertzel C., Holloway, Alison C.
Publicado 2008

Impaired Ca(2+) Signaling in β-Cells Lacking Leptin Receptors by Cre-loxP Recombination

por Tudurí, Eva, Bruin, Jennifer E., Denroche, Heather C., Fox, Jessica K., Johnson, James D., Kieffer, Timothy J.
Publicado 2013

Fetal and neonatal dioxin exposure causes sex-specific metabolic alterations in mice

por Hoyeck, Myriam P, Merhi, Rayanna C, Tulloch, Cameron, McCormick, Kaitlyn, Mohammed Abu Hossain, Shahen, Hanson, Antonio A, Bruin, Jennifer E
Publicado 2023

Leptin Administration Enhances Islet Transplant Performance in Diabetic Mice

por Denroche, Heather C., Quong, Whitney L., Bruin, Jennifer E., Tudurí, Eva, Asadi, Ali, Glavas, Maria M., Fox, Jessica K., Kieffer, Timothy J.
Publicado 2013

Long-term metabolic consequences of acute dioxin exposure differ between male and female mice

por Hoyeck, Myriam P., Blair, Hannah, Ibrahim, Muna, Solanki, Shivani, Elsawy, Mariam, Prakash, Arina, Rick, Kayleigh R. C., Matteo, Geronimo, O’Dwyer, Shannon, Bruin, Jennifer E.
Publicado 2020

Functional cytochrome P450 1A enzymes are induced in mouse and human islets following pollutant exposure

por Ibrahim, Muna, MacFarlane, Erin M., Matteo, Geronimo, Hoyeck, Myriam P., Rick, Kayleigh R. C., Farokhi, Salar, Copley, Catherine M., O’Dwyer, Shannon, Bruin, Jennifer E.
Publicado 2019

Prolonged Low-Dose Dioxin Exposure Impairs Metabolic Adaptability to High-Fat Diet Feeding in Female but Not Male Mice

por Matteo, Geronimo, Hoyeck, Myriam P, Blair, Hannah L, Zebarth, Julia, Rick, Kayleigh R C, Williams, Andrew, Gagné, Rémi, Buick, Julie K, Yauk, Carole L, Bruin, Jennifer E
Publicado 2021

Female mice exposed to low doses of dioxin during pregnancy and lactation have increased susceptibility to diet-induced obesity and diabetes

por Hoyeck, Myriam P., Merhi, Rayanna C., Blair, Hannah L., Spencer, C. Duncan, Payant, Mikayla A., Martin Alfonso, Diana I., Zhang, Melody, Matteo, Geronimo, Chee, Melissa J., Bruin, Jennifer E.
Publicado 2020

Treating Diet-Induced Diabetes and Obesity with Human Embryonic Stem Cell-Derived Pancreatic Progenitor Cells and Antidiabetic Drugs

por Bruin, Jennifer E., Saber, Nelly, Braun, Natalie, Fox, Jessica K., Mojibian, Majid, Asadi, Ali, Drohan, Campbell, O’Dwyer, Shannon, Rosman-Balzer, Diana S., Swiss, Victoria A., Rezania, Alireza, Kieffer, Timothy J.
Publicado 2015

Maturation of Human Embryonic Stem Cell–Derived Pancreatic Progenitors Into Functional Islets Capable of Treating Pre-existing Diabetes in Mice

por Rezania, Alireza, Bruin, Jennifer E., Riedel, Michael J., Mojibian, Majid, Asadi, Ali, Xu, Jean, Gauvin, Rebecca, Narayan, Kavitha, Karanu, Francis, O’Neil, John J., Ao, Ziliang, Warnock, Garth L., Kieffer, Timothy J.
Publicado 2012

Deletion of pancreas-specific miR-216a reduces beta-cell mass and inhibits pancreatic cancer progression in mice

por Erener, Suheda, Ellis, Cara E., Ramzy, Adam, Glavas, Maria M., O’Dwyer, Shannon, Pereira, Sandra, Wang, Tom, Pang, Janice, Bruin, Jennifer E., Riedel, Michael J., Baker, Robert K., Webber, Travis D., Lesina, Marina, Blüher, Matthias, Algül, Hana, Kopp, Janel L., Herzig, Stephan, Kieffer, Timothy J.
Publicado 2021