Plasma phospho-tau in Alzheimer’s disease: towards diagnostic and therapeutic trial applications

por Gonzalez-Ortiz, Fernando, Kac, Przemysław R., Brum, Wagner S., Zetterberg, Henrik, Blennow, Kaj, Karikari, Thomas K.
Publicado 2023

Impact of the COVID-19 pandemic on early career dementia researchers: A global online survey

por Bartels, Sara Laureen, Shaaban, C. Elizabeth, Brum, Wagner S., Welikovitch, Lindsay A., Folarin, Royhaan, Smith, Adam
Publicado 2022

Differences between blood and cerebrospinal fluid glial fibrillary Acidic protein levels: The effect of sample stability

por Simrén, Joel, Weninger, Haley, Brum, Wagner S., Khalil, Shilla, Benedet, Andréa L., Blennow, Kaj, Zetterberg, Henrik, Ashton, Nicholas J.
Publicado 2022

The accuracy and robustness of plasma biomarker models for amyloid PET positivity

por Benedet, Andréa L., Brum, Wagner S., Hansson, Oskar, Karikari, Thomas K., Zimmer, Eduardo R., Zetterberg, Henrik, Blennow, Kaj, Ashton, Nicholas J.
Publicado 2022

Functional Cognitive Disorder Presents High Frequency and Distinct Clinical Profile in Patients With Low Education

por Borelli, Wyllians Vendramini, de Senna, Priscylla Nunes, Brum, Wagner Scheeren, Schumacher-Schuh, Artur Francisco, Zimmer, Eduardo R., Fagundes Chaves, Márcia Lorena, Castilhos, Raphael Machado
Publicado 2022

Soluble amyloid-beta isoforms predict downstream Alzheimer’s disease pathology

por Povala, Guilherme, Bellaver, Bruna, De Bastiani, Marco Antônio, Brum, Wagner S., Ferreira, Pamela C. L., Bieger, Andrei, Pascoal, Tharick A., Benedet, Andrea L., Souza, Diogo O., Araujo, Ricardo M., Zatt, Bruno, Rosa-Neto, Pedro, Zimmer, Eduardo R.
Publicado 2021

A three‐range approach enhances the prognostic utility of CSF biomarkers in Alzheimer's disease

por Brum, Wagner S., de Bastiani, Marco Antônio, Bieger, Andrei, Therriault, Joseph, Ferrari‐Souza, João P., Benedet, Andréa L., Saha‐Chaudhuri, Paramita, Souza, Diogo O., Ashton, Nicholas J., Zetterberg, Henrik, Pascoal, Tharick A., Karikari, Thomas, Blennow, Kaj, Rosa‐Neto, Pedro, Zimmer, Eduardo R.
Publicado 2022

CSF tau368/total-tau ratio reflects cognitive performance and neocortical tau better compared to p-tau181 and p-tau217 in cognitively impaired individuals

por Simrén, Joel, Brum, Wagner S., Ashton, Nicholas J., Benedet, Andrea L., Karikari, Thomas K., Kvartsberg, Hlin, Sjons, Emma, Lussier, Firoza Z., Chamoun, Mira, Stevenson, Jenna, Hopewell, Robert, Pallen, Vanessa, Ye, Keqiang, Pascoal, Tharick A., Zetterberg, Henrik, Rosa-Neto, Pedro, Blennow, Kaj
Publicado 2022

A two-step workflow based on plasma p-tau217 to screen for amyloid β positivity with further confirmatory testing only in uncertain cases

por Brum, Wagner S., Cullen, Nicholas C., Janelidze, Shorena, Ashton, Nicholas J., Zimmer, Eduardo R., Therriault, Joseph, Benedet, Andrea L., Rahmouni, Nesrine, Tissot, Cécile, Stevenson, Jenna, Servaes, Stijn, Triana-Baltzer, Gallen, Kolb, Hartmuth C., Palmqvist, Sebastian, Stomrud, Erik, Rosa-Neto, Pedro, Blennow, Kaj, Hansson, Oskar
Publicado 2023

Cerebrospinal fluid p-tau231 as an early indicator of emerging pathology in Alzheimer's disease

por Ashton, Nicholas J., Benedet, Andréa L., Pascoal, Tharick A., Karikari, Thomas K., Lantero-Rodriguez, Juan, Brum, Wagner S., Mathotaarachchi, Sulantha, Therriault, Joseph, Savard, Melissa, Chamoun, Mira, Stoops, Erik, Francois, Cindy, Vanmechelen, Eugeen, Gauthier, Serge, Zimmer, Eduardo R., Zetterberg, Henrik, Blennow, Kaj, Rosa-Neto, Pedro
Publicado 2022

Mass spectrometric simultaneous quantification of tau species in plasma shows differential associations with amyloid and tau pathologies

por Montoliu-Gaya, Laia, Benedet, Andréa L., Tissot, Cécile, Vrillon, Agathe, Ashton, Nicholas J., Brum, Wagner S., Lantero-Rodriguez, Juan, Stevenson, Jenna, Nilsson, Johanna, Sauer, Mathias, Rahmouni, Nesrine, Brinkmalm, Gunnar, Lussier, Firoza Z., Pascoal, Tharick A., Skoog, Ingmar, Kern, Silke, Zetterberg, Henrik, Paquet, Claire, Gobom, Johan, Rosa-Neto, Pedro, Blennow, Kaj
Publicado 2023

Prevalence and Clinical Implications of a β-Amyloid–Negative, Tau-Positive Cerebrospinal Fluid Biomarker Profile in Alzheimer Disease

por Erickson, Pontus, Simrén, Joel, Brum, Wagner S., Ennis, Gilda E., Kollmorgen, Gwendlyn, Suridjan, Ivonne, Langhough, Rebecca, Jonaitis, Erin M., Van Hulle, Carol A., Betthauser, Tobey J., Carlsson, Cynthia M., Asthana, Sanjay, Ashton, Nicholas J., Johnson, Sterling C., Shaw, Leslie M., Blennow, Kaj, Andreasson, Ulf, Bendlin, Barbara B., Zetterberg, Henrik
Publicado 2023

Clinical performance and head-to-head comparison of CSF p-tau235 with p-tau181, p-tau217 and p-tau231 in two memory clinic cohorts

por Lantero-Rodriguez, Juan, Vrillon, Agathe, Fernández-Lebrero, Aida, Ortiz-Romero, Paula, Snellman, Anniina, Montoliu-Gaya, Laia, Brum, Wagner S., Cognat, Emmanuel, Dumurgier, Julien, Puig-Pijoan, Albert, Navalpotro-Gómez, Irene, García-Escobar, Greta, Karikari, Thomas K., Vanmechelen, Eugeen, Ashton, Nicholas J., Zetterberg, Henrik, Suárez-Calvet, Marc, Paquet, Claire, Blennow, Kaj
Publicado 2023

Differential roles of Aβ42/40, p-tau231 and p-tau217 for Alzheimer’s trial selection and disease monitoring

por Ashton, Nicholas J., Janelidze, Shorena, Mattsson-Carlgren, Niklas, Binette, Alexa Pichet, Strandberg, Olof, Brum, Wagner S., Karikari, Thomas K., González-Ortiz, Fernándo, Di Molfetta, Guglielmo, Meda, Francisco J., Jonaitis, Erin M., Koscik, Rebecca Langhough, Cody, Karly, Betthauser, Tobey J., Li, Yan, Vanmechelen, Eugeen, Palmqvist, Sebastian, Stomrud, Erik, Bateman, Randall J., Zetterberg, Henrik, Johnson, Sterling C., Blennow, Kaj, Hansson, Oskar
Publicado 2022

Diagnostic accuracy of the plasma ALZpath pTau217 immunoassay to identify Alzheimer’s disease pathology

por Ashton, Nicholas J., Brum, Wagner S., Di Molfetta, Guglielmo, Benedet, Andrea L., Arslan, Burak, Jonatis, Erin, Langhough, Rebecca E., Cody, Karly, Wilson, Rachael, Carlsson, Cynthia M., Vanmechelen, Eugeen, Montoliu-Gaya, Laia, Lantero-Rodriguez, Juan, Rahmouni, Nesrine, Tissot, Cecile, Stevenson, Jenna, Servaes, Stijn, Therriault, Joseph, Pascoal, Tharick, Lleó, Alberto, Alcolea, Daniel, Fortea, Juan, Rosa-Neto, Pedro, Johnson, Sterling, Jeromin, Andreas, Blennow, Kaj, Zetterberg, Henrik
Publicado 2023

Astrocyte biomarker signatures of amyloid-β and tau pathologies in Alzheimer’s disease

por Ferrari-Souza, João Pedro, Ferreira, Pâmela C. L., Bellaver, Bruna, Tissot, Cécile, Wang, Yi-Ting, Leffa, Douglas T., Brum, Wagner S., Benedet, Andréa L., Ashton, Nicholas J., De Bastiani, Marco Antônio, Rocha, Andréia, Therriault, Joseph, Lussier, Firoza Z., Chamoun, Mira, Servaes, Stijn, Bezgin, Gleb, Kang, Min Su, Stevenson, Jenna, Rahmouni, Nesrine, Pallen, Vanessa, Poltronetti, Nina Margherita, Klunk, William E., Tudorascu, Dana L., Cohen, Ann D., Villemagne, Victor L., Gauthier, Serge, Blennow, Kaj, Zetterberg, Henrik, Souza, Diogo O., Karikari, Thomas K., Zimmer, Eduardo R., Rosa-Neto, Pedro, Pascoal, Tharick A.
Publicado 2022

Association of Phosphorylated Tau Biomarkers With Amyloid Positron Emission Tomography vs Tau Positron Emission Tomography

por Therriault, Joseph, Vermeiren, Marie, Servaes, Stijn, Tissot, Cécile, Ashton, Nicholas J., Benedet, Andréa Lessa, Karikari, Thomas K., Lantero-Rodriguez, Juan, Brum, Wagner S., Lussier, Firoza Z., Bezgin, Gleb, Stevenson, Jenna, Rahmouni, Nesrine, Kunach, Peter, Wang, Yi-Ting, Fernandez-Arias, Jaime, Socualaya, Kely Quispialaya, Macedo, Arthur C., Ferrari-Souza, João Pedro, Ferreira, Pâmela C. L., Bellaver, Bruna, Leffa, Douglas T., Zimmer, Eduardo R., Vitali, Paolo, Soucy, Jean-Paul, Triana-Baltzer, Gallen, Kolb, Hartmuth C., Pascoal, Tharick A., Saha-Chaudhuri, Paramita, Gauthier, Serge, Zetterberg, Henrik, Blennow, Kaj, Rosa-Neto, Pedro
Publicado 2022