Src Cooperates with Oncogenic Ras in Tumourigenesis via the JNK and PI3K Pathways in Drosophila epithelial Tissue

por Poon, Carole L.C., Brumby, Anthony M., Richardson, Helena E.
Publicado 2018

Loss of the Drosophila cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signaling

por Doggett, Karen, Grusche, Felix A, Richardson, Helena E, Brumby, Anthony M
Publicado 2011

In Drosophila, RhoGEF2 cooperates with activated Ras in tumorigenesis through a pathway involving Rho1–Rok–Myosin-II and JNK signalling

por Khoo, Peytee, Allan, Kirsten, Willoughby, Lee, Brumby, Anthony M., Richardson, Helena E.
Publicado 2013

scribble mutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs

por Leong, Gregory R, Goulding, Karen R, Amin, Nancy, Richardson, Helena E, Brumby, Anthony M
Publicado 2009

Cooperation of the BTB-Zinc finger protein, Abrupt, with cytoskeletal regulators in Drosophila epithelial tumorigenesis

por Turkel, Nezaket, Portela, Marta, Poon, Carole, Li, Jason, Brumby, Anthony M., Richardson, Helena E.
Publicado 2015

BTB-Zinc Finger Oncogenes Are Required for Ras and Notch-Driven Tumorigenesis in Drosophila

por Doggett, Karen, Turkel, Nezaket, Willoughby, Lee F., Ellul, Jason, Murray, Michael J., Richardson, Helena E., Brumby, Anthony M.
Publicado 2015

An in vivo large-scale chemical screening platform using Drosophila for anti-cancer drug discovery

por Willoughby, Lee F., Schlosser, Tanja, Manning, Samuel A., Parisot, John P., Street, Ian P., Richardson, Helena E., Humbert, Patrick O., Brumby, Anthony M.
Publicado 2013

The BTB-zinc Finger Transcription Factor Abrupt Acts as an Epithelial Oncogene in Drosophila melanogaster through Maintaining a Progenitor-like Cell State

por Turkel, Nezaket, Sahota, Virender K., Bolden, Jessica E., Goulding, Karen R., Doggett, Karen, Willoughby, Lee F., Blanco, Enrique, Martin-Blanco, Enrique, Corominas, Montserrat, Ellul, Jason, Aigaki, Toshiro, Richardson, Helena E., Brumby, Anthony M.
Publicado 2013