BRAF inhibitors in colorectal cancer: Toward a differentiation therapy?

por Herr, Ricarda, Brummer, Tilman
Publicado 2015

Function, regulation and pathological roles of the Gab/DOS docking proteins

por Wöhrle, Franziska U, Daly, Roger J, Brummer, Tilman
Publicado 2009

Global gene expression profiling analysis reveals reduction of stemness after B-RAF inhibition in colorectal cancer cell lines

por Boerries, Melanie, Herr, Ricarda, Brummer, Tilman, Busch, Hauke
Publicado 2015

Immune modulatory effects of oncogenic KRAS in cancer

por Hamarsheh, Shaima’a, Groß, Olaf, Brummer, Tilman, Zeiser, Robert
Publicado 2020

A novel MCF-10A line allowing conditional oncogene expression in 3D culture

por Herr, Ricarda, Wöhrle, Franziska U, Danke, Christina, Berens, Christian, Brummer, Tilman
Publicado 2011

BRAF(V600E) drives dedifferentiation in small intestinal and colonic organoids and cooperates with mutant p53 and Apc loss in transformation

por Reischmann, Nadine, Andrieux, Geoffroy, Griffin, Ricarda, Reinheckel, Thomas, Boerries, Melanie, Brummer, Tilman
Publicado 2020

Onco-immunomodulatory properties of pharmacological interference with RAS-RAF-MEK-ERK pathway hyperactivation

por Avery, Thomas Yul, Köhler, Natalie, Zeiser, Robert, Brummer, Tilman, Ruess, Dietrich Alexander
Publicado 2022

Degradome-focused RNA interference screens to identify proteases important for breast cancer cell growth

por Hölzen, Lena, Syré, Kerstin, Mitschke, Jan, Brummer, Tilman, Miething, Cornelius, Reinheckel, Thomas
Publicado 2022

Effects of RAF inhibitors on PI3K/AKT signalling depend on mutational status of the RAS/RAF signalling axis

por Fritsche-Guenther, Raphaela, Witzel, Franziska, Kempa, Stefan, Brummer, Tilman, Sers, Christine, Blüthgen, Nils
Publicado 2016

Analysis of RAS and drug induced homo- and heterodimerization of RAF and KSR1 proteins in living cells using split Nanoluc luciferase

por Rohrer, Lino, Spohr, Corinna, Beha, Carina, Griffin, Ricarda, Braun, Sandra, Halbach, Sebastian, Brummer, Tilman
Publicado 2023

PKD controls mitotic Golgi complex fragmentation through a Raf–MEK1 pathway

por Kienzle, Christine, Eisler, Stephan A., Villeneuve, Julien, Brummer, Tilman, Olayioye, Monilola A., Hausser, Angelika
Publicado 2013

The EMT-activator ZEB1 induces bone metastasis associated genes including BMP-inhibitors

por Mock, Kerstin, Preca, Bogdan-Tiberius, Brummer, Tilman, Brabletz, Simone, Stemmler, Marc P., Brabletz, Thomas
Publicado 2015

Axitinib and sorafenib are potent in tyrosine kinase inhibitor resistant chronic myeloid leukemia cells

por Halbach, Sebastian, Hu, Zehan, Gretzmeier, Christine, Ellermann, Julia, Wöhrle, Franziska U., Dengjel, Jörn, Brummer, Tilman
Publicado 2016

Dynamic transcriptome analysis reveals signatures of paradoxical effect of vemurafenib on human dermal fibroblasts

por Corrales, Eyleen, Levit-Zerdoun, Ella, Metzger, Patrick, Kowar, Silke, Ku, Manching, Brummer, Tilman, Boerries, Melanie
Publicado 2021

Alterations of Gab2 signalling complexes in imatinib and dasatinib treated chronic myeloid leukaemia cells

por Halbach, Sebastian, Rigbolt, Kristoffer TG, Wöhrle, Franziska U, Diedrich, Britta, Gretzmeier, Christine, Brummer, Tilman, Dengjel, Jörn
Publicado 2013

Specific role of RhoC in tumor invasion and metastasis

por Lang, Sarah, Busch, Hauke, Boerries, Melanie, Brummer, Tilman, Timme, Sylvia, Lassmann, Silke, Aktories, Klaus, Schmidt, Gudula
Publicado 2017

Targeting oncogenic Ras by the Clostridium perfringens toxin TpeL

por Schorch, Björn, Heni, Hannah, Zahaf, Nour-Imene, Brummer, Tilman, Mione, Marina, Schmidt, Gudula, Papatheodorou, Panagiotis, Aktories, Klaus
Publicado 2018

Strong negative feedback from Erk to Raf confers robustness to MAPK signalling

por Fritsche-Guenther, Raphaela, Witzel, Franziska, Sieber, Anja, Herr, Ricarda, Schmidt, Nadine, Braun, Sandra, Brummer, Tilman, Sers, Christine, Blüthgen, Nils
Publicado 2011

RNA interference screens discover proteases as synthetic lethal partners of PI3K inhibition in breast cancer cells

por Hölzen, Lena, Mitschke, Jan, Schönichen, Claudia, Hess, Maria Elena, Ehrenfeld, Sophia, Boerries, Melanie, Miething, Cornelius, Brummer, Tilman, Reinheckel, Thomas
Publicado 2022

Exometabolom analysis of breast cancer cell lines: Metabolic signature

por Willmann, Lucas, Erbes, Thalia, Halbach, Sebastian, Brummer, Tilman, Jäger, Markus, Hirschfeld, Marc, Fehm, Tanja, Neubauer, Hans, Stickeler, Elmar, Kammerer, Bernd
Publicado 2015