Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax)

por Leverson, J D, Zhang, H, Chen, J, Tahir, S K, Phillips, D C, Xue, J, Nimmer, P, Jin, S, Smith, M, Xiao, Y, Kovar, P, Tanaka, A, Bruncko, M, Sheppard, G S, Wang, L, Gierke, S, Kategaya, L, Anderson, D J, Wong, C, Eastham-Anderson, J, Ludlam, M J C, Sampath, D, Fairbrother, W J, Wertz, I, Rosenberg, S H, Tse, C, Elmore, S W, Souers, A J
Publicado 2015