Rapid Temporal Control of Foxp3 Protein Degradation by Sirtuin-1

por van Loosdregt, Jorg, Brunen, Diede, Fleskens, Veerle, Pals, Cornelieke E. G. M., Lam, Eric W. F., Coffer, Paul J.
Publicado 2011

Systematic discovery of mutation-specific synthetic lethals by mining pan-cancer human primary tumor data

por Sinha, Subarna, Thomas, Daniel, Chan, Steven, Gao, Yang, Brunen, Diede, Torabi, Damoun, Reinisch, Andreas, Hernandez, David, Chan, Andy, Rankin, Erinn B., Bernards, Rene, Majeti, Ravindra, Dill, David L.
Publicado 2017

Intrinsic resistance to PIM kinase inhibition in AML through p38α-mediated feedback activation of mTOR signaling

por Brunen, Diede, García-Barchino, María José, Malani, Disha, Basheer, Noorjahan Jagalur, Lieftink, Cor, Beijersbergen, Roderick L., Murumägi, Astrid, Porkka, Kimmo, Wolf, Maija, Zwaan, C. Michel, Fornerod, Maarten, Kallioniemi, Olli, Martínez-Climent, José Ángel, Bernards, René
Publicado 2016

A reversible SRC-relayed COX2 inflammatory program drives resistance to BRAF and EGFR inhibition in BRAF(V600E) colorectal tumors

por Ruiz-Saenz, Ana, Atreya, Chloe E., Wang, Changjun, Pan, Bo, Dreyer, Courtney A., Brunen, Diede, Prahallad, Anirudh, Muñoz, Denise P., Ramms, Dana J., Burghi, Valeria, Spassov, Danislav S., Fewings, Eleanor, Hwang, Yeonjoo C., Cowdrey, Cynthia, Moelders, Christina, Schwarzer, Cecilia, Wolf, Denise M., Hann, Byron, VandenBerg, Scott R., Shokat, Kevan, Moasser, Mark M., Bernards, René, Gutkind, J. Silvio, van ‘t Veer, Laura J., Coppé, Jean-Philippe
Publicado 2023