Silibinin and SARS-CoV-2: Dual Targeting of Host Cytokine Storm and Virus Replication Machinery for Clinical Management of COVID-19 Patients

por Bosch-Barrera, Joaquim, Martin-Castillo, Begoña, Buxó, Maria, Brunet, Joan, Encinar, José Antonio, Menendez, Javier A.
Publicado 2020

Ethics competences in the undergraduate medical education curriculum: the Spanish experience

por Ferreira-Padilla, Guillermo, Ferrández-Antón, Teresa, Lolas-Stepke, Fernando, Almeida-Cabrera, Rut, Brunet, Joan, Bosch-Barrera, Joaquim
Publicado 2016

Cancer develops, progresses and responds to therapies through restricted perturbation of the protein–protein interaction network

por Serra-Musach, Jordi, Aguilar, Helena, Iorio, Francesco, Comellas, Francesc, Berenguer, Antoni, Brunet, Joan, Saez-Rodriguez, Julio, Pujana, Miguel Angel
Publicado 2012

Fatty acid synthase expression and its association with clinico-histopathological features in triple-negative breast cancer

por Giró-Perafita, Ariadna, Sarrats, Ariadna, Pérez-Bueno, Ferran, Oliveras, Glòria, Buxó, Maria, Brunet, Joan, Viñas, Gemma, Miquel, Teresa Puig
Publicado 2017

SEOM clinical guideline on heritable TP53-related cancer syndrome (2022)

por Sánchez-Heras, Ana Beatriz, Ramon y Cajal, Teresa, Pineda, Marta, Aguirre, Elena, Graña, Begoña, Chirivella, Isabel, Balmaña, Judit, Brunet, Joan
Publicado 2023

Lack of evidence for germline WWP1 pathogenic variants in gastrointestinal polyposis and other phenotypes suggestive of PTEN-hamartoma-tumor syndrome

por Gonzalez-Abuin, Noemi, Pons, Tirso, Fuster, Teresa, Quintana, Isabel, Terradas, Mariona, Aiza, Gemma, Brunet, Joan, Capellá, Gabriel, Hampel, Heather, Valle, Laura
Publicado 2023

Olive oil's bitter principle reverses acquired autoresistance to trastuzumab (Herceptin™) in HER2-overexpressing breast cancer cells

por Menendez, Javier A, Vazquez-Martin, Alejandro, Colomer, Ramon, Brunet, Joan, Carrasco-Pancorbo, Alegria, Garcia-Villalba, Rocio, Fernandez-Gutierrez, Alberto, Segura-Carretero, Antonio
Publicado 2007

Synthetic lethal interaction of cetuximab with MEK1/2 inhibition in NRAS-mutant metastatic colorectal cancer

por Queralt, Bernardo, Cuyàs, Elisabet, Bosch-Barrera, Joaquim, Massaguer, Anna, de Llorens, Rafael, Martin-Castillo, Begoña, Brunet, Joan, Salazar, Ramon, Menendez, Javier A.
Publicado 2016

BRCA1 haploinsufficiency cell-autonomously activates RANKL expression and generates denosumab-responsive breast cancer-initiating cells

por Cuyàs, Elisabet, Corominas-Faja, Bruna, Muñoz-San María, Martín, Martin-Castillo, Begoña, Lupu, Ruth, Brunet, Joan, Bosch-Barrera, Joaquim, Menendez, Javier A
Publicado 2017

Resveratrol targets PD-L1 glycosylation and dimerization to enhance antitumor T-cell immunity

por Verdura, Sara, Cuyàs, Elisabet, Cortada, Eric, Brunet, Joan, Lopez-Bonet, Eugeni, Martin-Castillo, Begoña, Bosch-Barrera, Joaquim, Encinar, José Antonio, Menendez, Javier A.
Publicado 2020

Evaluation of CNV detection tools for NGS panel data in genetic diagnostics

por Moreno-Cabrera, José Marcos, del Valle, Jesús, Castellanos, Elisabeth, Feliubadaló, Lidia, Pineda, Marta, Brunet, Joan, Serra, Eduard, Capellà, Gabriel, Lázaro, Conxi, Gel, Bernat
Publicado 2020

Response of brain metastasis from lung cancer patients to an oral nutraceutical product containing silibinin

por Bosch-Barrera, Joaquim, Sais, Elia, Cañete, Noemí, Marruecos, Jordi, Cuyàs, Elisabet, Izquierdo, Angel, Porta, Rut, Haro, Manel, Brunet, Joan, Pedraza, Salvador, Menendez, Javier A.
Publicado 2016

RNA assay identifies a previous misclassification of BARD1 c.1977A>G variant

por Rofes, Paula, Pineda, Marta, Feliubadaló, Lídia, Menéndez, Mireia, de Cid, Rafael, Gómez, Carolina, Montes, Eva, Capellá, Gabriel, Brunet, Joan, del Valle, Jesús, Lázaro, Conxi
Publicado 2021

Psychosocial problems in women attending French, German and Spanish genetics clinics before and after targeted or multigene testing results: an observational prospective study

por Brédart, Anne, Kop, Jean-Luc, Dick, Julia, Cano, Alejandra, De Pauw, Antoine, Anota, Amélie, Brunet, Joan, Devilee, Peter, Stoppa-Lyonnet, Dominique, Schmutzler, Rita, Dolbeault, Sylvie
Publicado 2019

The LSD1 inhibitor iadademstat (ORY-1001) targets SOX2-driven breast cancer stem cells: a potential epigenetic therapy in luminal-B and HER2-positive breast cancer subtypes

por Cuyàs, Elisabet, Gumuzio, Juan, Verdura, Sara, Brunet, Joan, Bosch-Barrera, Joaquim, Martin-Castillo, Begoña, Alarcón, Tomás, Encinar, José Antonio, Martin, Ángel G., Menendez, Javier A.
Publicado 2020

Clinical Management of COVID-19 in Cancer Patients with the STAT3 Inhibitor Silibinin

por Bosch-Barrera, Joaquim, Roqué, Ariadna, Teixidor, Eduard, Carmona-Garcia, Maria Carmen, Arbusà, Aina, Brunet, Joan, Martin-Castillo, Begoña, Cuyàs, Elisabet, Verdura, Sara, Menendez, Javier A.
Publicado 2021

Functional and Structural Analysis of C-Terminal BRCA1 Missense Variants

por Quiles, Francisco, Fernández-Rodríguez, Juana, Mosca, Roberto, Feliubadaló, Lídia, Tornero, Eva, Brunet, Joan, Blanco, Ignacio, Capellá, Gabriel, Pujana, Miquel Àngel, Aloy, Patrick, Monteiro, Alvaro, Lázaro, Conxi
Publicado 2013

Potential Involvement of NSD1, KRT24 and ACACA in the Genetic Predisposition to Colorectal Cancer

por Quintana, Isabel, Mur, Pilar, Terradas, Mariona, García-Mulero, Sandra, Aiza, Gemma, Navarro, Matilde, Piñol, Virginia, Brunet, Joan, Moreno, Victor, Sanz-Pamplona, Rebeca, Capellá, Gabriel, Valle, Laura
Publicado 2022

Metformin Is a Direct SIRT1-Activating Compound: Computational Modeling and Experimental Validation

por Cuyàs, Elisabet, Verdura, Sara, Llorach-Parés, Laura, Fernández-Arroyo, Salvador, Joven, Jorge, Martin-Castillo, Begoña, Bosch-Barrera, Joaquim, Brunet, Joan, Nonell-Canals, Alfons, Sanchez-Martinez, Melchor, Menendez, Javier A.
Publicado 2018

NTHL1 biallelic mutations seldom cause colorectal cancer, serrated polyposis or a multi-tumor phenotype, in absence of colorectal adenomas

por Belhadj, Sami, Quintana, Isabel, Mur, Pilar, Munoz-Torres, Pau M., Alonso, M. Henar, Navarro, Matilde, Terradas, Mariona, Piñol, Virginia, Brunet, Joan, Moreno, Victor, Lázaro, Conxi, Capellá, Gabriel, Valle, Laura
Publicado 2019