Regulated cell death pathways in doxorubicin-induced cardiotoxicity

por Christidi, Effimia, Brunham, Liam R.
Publicado 2021

Hunting human disease genes: lessons from the past, challenges for the future

por Brunham, Liam R., Hayden, Michael R.
Publicado 2013

Association of Monogenic vs Polygenic Hypercholesterolemia With Risk of Atherosclerotic Cardiovascular Disease

por Trinder, Mark, Francis, Gordon A., Brunham, Liam R.
Publicado 2020

Causal Inference for Genetically Determined Levels of High-Density Lipoprotein Cholesterol and Risk of Infectious Disease

por Trinder, Mark, Walley, Keith R., Boyd, John H., Brunham, Liam R.
Publicado 2020

Patient Perspectives Regarding Genetic Testing for Familial Hypercholesterolemia

por Marchand, Miles, Chen, Victoria, Trinder, Mark, Cermakova, Lubomira, Brunham, Liam R.
Publicado 2021

Can Achilles tendon xanthoma be distinguished from Achilles tendinopathy using Dixon method MRI? A cross-sectional exploratory study

por Zahradnik, Thomas Michael, Cresswell, Mark, Squier, Kip, Waugh, Charlotte, Brunham, Liam, Screen, Hazel, Scott, Alex
Publicado 2021

Sex Differences in the Presentation, Treatment, and Outcome of Patients With Familial Hypercholesterolemia

por Ryzhaya, Natalia, Cermakova, Lubomira, Trinder, Mark, Ruel, Isabelle, Coutinho, Thais, Genest, Jacques, Brunham, Liam R.
Publicado 2021

RARG S427L attenuates the DNA repair response to doxorubicin in induced pluripotent stem cell-derived cardiomyocytes

por Huang, Haojun, Christidi, Effimia, Shafaattalab, Sanam, Davis, Margot K., Tibbits, Glen F., Brunham, Liam R.
Publicado 2022

Accurate Prediction of the Functional Significance of Single Nucleotide Polymorphisms and Mutations in the ABCA1 Gene

por Brunham, Liam R, Singaraja, Roshni R, Pape, Terry D, Kejariwal, Anish, Thomas, Paul D, Hayden, Michael R
Publicado 2005

Polygenic Contribution to Low-Density Lipoprotein Cholesterol Levels and Cardiovascular Risk in Monogenic Familial Hypercholesterolemia

por Trinder, Mark, Paquette, Martine, Cermakova, Lubomira, Ban, Matthew R., Hegele, Robert A., Baass, Alexis, Brunham, Liam R.
Publicado 2020

Premature Atherosclerotic Cardiovascular Disease: Trends in Incidence, Risk Factors, and Sex‐Related Differences, 2000 to 2016

por Vikulova, Diana N., Grubisic, Maja, Zhao, Yinshan, Lynch, Kelsey, Humphries, Karin H., Pimstone, Simon N., Brunham, Liam R.
Publicado 2019

The effects of cholesterol accumulation on Achilles tendon biomechanics: A cross-sectional study

por Squier, Kipling, Scott, Alexander, Hunt, Michael A., Brunham, Liam R., Wilson, David R., Screen, Hazel, Waugh, Charlie M.
Publicado 2021

Priorities for Services in Young Patients With Atherosclerotic Cardiovascular Disease and Their Family Members: An Exploratory Mixed-Methods Study

por Cho, Raymond Y., Weng, Jian, Lynch, Kelsey, Ng, Phoebe, Brown, Chad, Hoens, Alison M., Barry, Kevin, Brunham, Liam R., Pimstone, Simon
Publicado 2019

Prevalence and characteristics of adverse drug reactions at admission to hospital: a prospective observational study

por Chan, Sze Ling, Ang, Xiaohui, Sani, Levana L., Ng, Hong Yen, Winther, Michael D., Liu, Jian Jun, Brunham, Liam R., Chan, Alexandre
Publicado 2016

Variation in RARG increases susceptibility to doxorubicin-induced cardiotoxicity in patient specific induced pluripotent stem cell-derived cardiomyocytes

por Christidi, Effimia, Huang, Haojun, Shafaattalab, Sanam, Maillet, Agnes, Lin, Eric, Huang, Kate, Laksman, Zachary, Davis, Margot K., Tibbits, Glen F., Brunham, Liam R.
Publicado 2020

Carriers of Loss-of-Function Mutations in ABCA1 Display Pancreatic β-Cell Dysfunction

por Vergeer, Menno, Brunham, Liam R., Koetsveld, Joris, Kruit, Janine K., Verchere, C. Bruce, Kastelein, John J.P., Hayden, Michael R., Stroes, Erik S.G.
Publicado 2010

Ibrutinib Displays Atrial-Specific Toxicity in Human Stem Cell-Derived Cardiomyocytes

por Shafaattalab, Sanam, Lin, Eric, Christidi, Effimia, Huang, Haojun, Nartiss, Yulia, Garcia, Analucia, Lee, Jeehon, Protze, Stephanie, Keller, Gordon, Brunham, Liam, Tibbits, Glen F., Laksman, Zachary
Publicado 2019

Modeling Doxorubicin-Induced Cardiotoxicity in Human Pluripotent Stem Cell Derived-Cardiomyocytes

por Maillet, Agnes, Tan, Kim, Chai, Xiaoran, Sadananda, Singh N., Mehta, Ashish, Ooi, Jolene, Hayden, Michael R., Pouladi, Mahmoud A., Ghosh, Sujoy, Shim, Winston, Brunham, Liam R.
Publicado 2016

Association and clinical utility of NAT2 in the prediction of isoniazid-induced liver injury in Singaporean patients

por Chan, Sze Ling, Chua, Angeline Poh Gek, Aminkeng, Folefac, Chee, Cynthia Bin Eng, Jin, Shengnan, Loh, Marie, Gan, Suay Hong, Wang, Yee Tang, Brunham, Liam R.
Publicado 2017

Genetic diversity of variants involved in drug response and metabolism in Sri Lankan populations: implications for clinical implementation of pharmacogenomics

por Chan, Sze Ling, Samaranayake, Nilakshi, Ross, Colin J.D., Toh, Meng Tiak, Carleton, Bruce, Hayden, Michael R., Teo, Yik Ying, Dissanayake, Vajira H.W., Brunham, Liam R.
Publicado 2016